COTL1 | ENSG00000103187 | NCBI 23406

Details for: COTL1

Gene ID: 23406

Symbol: COTL1

Ensembl ID: ENSG00000103187

Description: coactosin like F-actin binding protein 1

Associated with

Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Neutrophil degranulation
(R-HSA-6798695)
Actin binding
(GO:0003779)
Actin filament
(GO:0005884)
Actin filament binding
(GO:0051015)
Biological_process
(GO:0008150)
Cortical actin cytoskeleton
(GO:0030864)
Cytosol
(GO:0005829)
Defense response to fungus
(GO:0050832)
Enzyme binding
(GO:0019899)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Ficolin-1-rich granule lumen
(GO:1904813)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulation of actin filament polymerization
(GO:0030833)
Secretory granule lumen
(GO:0034774)
Site of polarized growth
(GO:0030427)

Other Information

Proteins

Coactosin-like protein

Genular Protein ID: 2966148393

Symbol: COTL1_HUMAN

Name: Coactosin-like protein

UniProtKB Accession Codes:

Q14019 B2RDU3 D3DUL9 Q86XM5

Database IDs:

Citations:

PubMed ID: 9326934

Title: Homologous recombination of a flanking repeat gene cluster is a mechanism for a common contiguous gene deletion syndrome.

PubMed ID: 9326934

DOI: 10.1038/ng1097-154

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 11583571

Title: Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75.

PubMed ID: 11583571

DOI: 10.1042/0264-6021:3590255

PubMed ID: 11297527

Title: 5-lipoxygenase interacts with coactosin-like protein.

PubMed ID: 11297527

DOI: 10.1074/jbc.m011205200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 19807693

Title: Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.

PubMed ID: 19807693

DOI: 10.1042/bj20090856

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 15754059

Title: NMR structure of human coactosin-like protein.

PubMed ID: 15754059

DOI: 10.1007/s10858-004-3449-y

PubMed ID: 15459340

Title: Crystal structure of human coactosin-like protein at 1.9 A resolution.

PubMed ID: 15459340

DOI: 10.1110/ps.04937304

PubMed ID: 17070122

Title: Binding model of human coactosin-like protein with filament actin revealed by mutagenesis.

PubMed ID: 17070122

DOI: 10.1016/j.bbapap.2006.06.017

Sequence Information:

Length: 142
Mass: 15945
Checksum: A4B881DD8E89A35D
Sequence:

MATKIDKEAC RAAYNLVRDD GSAVIWVTFK YDGSTIVPGE QGAEYQHFIQ QCTDDVRLFA 
FVRFTTGDAM SKRSKFALIT WIGENVSGLQ RAKTGTDKTL VKEVVQNFAK EFVISDRKEL 
EEDFIKSELK KAGGANYDAQ TE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: COTL1

Associated with

Other Information

Homologous recombination of a flanking repeat gene cluster is a mechanism for a common contiguous gene deletion syndrome. PubMed ID: 9326934

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. PubMed ID: 12665801

Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75. PubMed ID: 11583571

5-lipoxygenase interacts with coactosin-like protein. PubMed ID: 11297527

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102. PubMed ID: 19807693

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

NMR structure of human coactosin-like protein. PubMed ID: 15754059

Crystal structure of human coactosin-like protein at 1.9 A resolution. PubMed ID: 15459340

Binding model of human coactosin-like protein with filament actin revealed by mutagenesis. PubMed ID: 17070122