Details for: SIRT1

Gene ID: 23411

Symbol: SIRT1

Ensembl ID: ENSG00000096717

Description: sirtuin 1

Associated with

Other Information

Genular Protein ID: 3320952216

Symbol: SIR1_HUMAN

Name: Regulatory protein SIR2 homolog 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10381378

Title: Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.

PubMed ID: 10381378

DOI: 10.1006/bbrc.1999.0897

PubMed ID: 12535671

Title: Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression.

PubMed ID: 12535671

DOI: 10.1016/s0006-291x(02)03020-6

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11672523

Title: hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.

PubMed ID: 11672523

DOI: 10.1016/s0092-8674(01)00527-x

PubMed ID: 12006491

Title: Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.

PubMed ID: 12006491

DOI: 10.1093/emboj/21.10.2383

PubMed ID: 12297502

Title: Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1.

PubMed ID: 12297502

DOI: 10.1074/jbc.m205670200

PubMed ID: 12939617

Title: Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.

PubMed ID: 12939617

DOI: 10.1038/nature01960

PubMed ID: 15152190

Title: Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

PubMed ID: 15152190

DOI: 10.1038/sj.emboj.7600244

PubMed ID: 14980222

Title: Mammalian SIRT1 represses forkhead transcription factors.

PubMed ID: 14980222

DOI: 10.1016/s0092-8674(04)00126-6

PubMed ID: 15126506

Title: FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1).

PubMed ID: 15126506

DOI: 10.1074/jbc.m401138200

PubMed ID: 15469825

Title: Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin.

PubMed ID: 15469825

DOI: 10.1016/j.molcel.2004.08.031

PubMed ID: 14976264

Title: Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase.

PubMed ID: 14976264

DOI: 10.1126/science.1094637

PubMed ID: 15205477

Title: Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase.

PubMed ID: 15205477

DOI: 10.1126/science.1099196

PubMed ID: 15692560

Title: Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation.

PubMed ID: 15692560

DOI: 10.1038/sj.emboj.7600570

PubMed ID: 16079181

Title: Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.

PubMed ID: 16079181

DOI: 10.1091/mbc.e05-01-0033

PubMed ID: 16166628

Title: Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications.

PubMed ID: 16166628

DOI: 10.1128/mcb.25.19.8456-8464.2005

PubMed ID: 15719057

Title: SIRT1 regulates HIV transcription via Tat deacetylation.

PubMed ID: 15719057

DOI: 10.1371/journal.pbio.0030041

PubMed ID: 15684044

Title: Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation.

PubMed ID: 15684044

DOI: 10.1073/pnas.0409875102

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 16892051

Title: Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage.

PubMed ID: 16892051

DOI: 10.1038/ncb1468

PubMed ID: 17620057

Title: Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1.

PubMed ID: 17620057

DOI: 10.1042/bj20070151

PubMed ID: 17680780

Title: Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription.

PubMed ID: 17680780

DOI: 10.1042/bj20070817

PubMed ID: 17290224

Title: Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo.

PubMed ID: 17290224

DOI: 10.1038/sj.emboj.7601563

PubMed ID: 17334224

Title: SIRT1 promotes DNA repair activity and deacetylation of Ku70.

PubMed ID: 17334224

DOI: 10.1038/emm.2007.2

PubMed ID: 16998810

Title: SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity.

PubMed ID: 16998810

DOI: 10.1002/jcp.20831

PubMed ID: 17505061

Title: Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor.

PubMed ID: 17505061

DOI: 10.1210/me.2006-0467

PubMed ID: 17964266

Title: Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity.

PubMed ID: 17964266

DOI: 10.1016/j.molcel.2007.08.030

PubMed ID: 17936707

Title: SIRT1 deacetylates and positively regulates the nuclear receptor LXR.

PubMed ID: 17936707

DOI: 10.1016/j.molcel.2007.07.032

PubMed ID: 17612497

Title: SIRT1 regulates the function of the Nijmegen breakage syndrome protein.

PubMed ID: 17612497

DOI: 10.1016/j.molcel.2007.05.029

PubMed ID: 17283066

Title: An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity.

PubMed ID: 17283066

DOI: 10.1128/mcb.01098-06

PubMed ID: 18004385

Title: SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation.

PubMed ID: 18004385

DOI: 10.1038/nature06268

PubMed ID: 18662546

Title: SIRT1 regulates circadian clock gene expression through PER2 deacetylation.

PubMed ID: 18662546

DOI: 10.1016/j.cell.2008.06.050

PubMed ID: 18485871

Title: Epigenetic control of rDNA loci in response to intracellular energy status.

PubMed ID: 18485871

DOI: 10.1016/j.cell.2008.03.030

PubMed ID: 18838864

Title: JNK2-dependent regulation of SIRT1 protein stability.

PubMed ID: 18838864

DOI: 10.4161/cc.7.19.6799

PubMed ID: 18329615

Title: Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation.

PubMed ID: 18329615

DOI: 10.1016/j.chom.2008.02.002

PubMed ID: 18203716

Title: Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation.

PubMed ID: 18203716

DOI: 10.1074/jbc.m709707200

PubMed ID: 18687677

Title: SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation.

PubMed ID: 18687677

DOI: 10.1074/jbc.m805711200

PubMed ID: 18235501

Title: DBC1 is a negative regulator of SIRT1.

PubMed ID: 18235501

DOI: 10.1038/nature06500

PubMed ID: 18235502

Title: Negative regulation of the deacetylase SIRT1 by DBC1.

PubMed ID: 18235502

DOI: 10.1038/nature06515

PubMed ID: 19107194

Title: Phosphorylation regulates SIRT1 function.

PubMed ID: 19107194

DOI: 10.1371/journal.pone.0004020

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18296641

Title: A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy.

PubMed ID: 18296641

DOI: 10.1073/pnas.0712145105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19236849

Title: Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2.

PubMed ID: 19236849

DOI: 10.1016/j.bbrc.2009.02.085

PubMed ID: 19220062

Title: Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.

PubMed ID: 19220062

DOI: 10.1021/bi802093g

PubMed ID: 19356714

Title: Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.

PubMed ID: 19356714

DOI: 10.1016/j.cmet.2009.02.006

PubMed ID: 19690166

Title: Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation.

PubMed ID: 19690166

DOI: 10.1074/jbc.m109.034165

PubMed ID: 19364925

Title: A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.

PubMed ID: 19364925

DOI: 10.1083/jcb.200809167

PubMed ID: 19188449

Title: hSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damage.

PubMed ID: 19188449

DOI: 10.1128/mcb.00552-08

PubMed ID: 20027304

Title: JNK1 phosphorylates SIRT1 and promotes its enzymatic activity.

PubMed ID: 20027304

DOI: 10.1371/journal.pone.0008414

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20203304

Title: SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells.

PubMed ID: 20203304

DOI: 10.1161/circresaha.109.215483

PubMed ID: 20097625

Title: Role of SIRT1 in homologous recombination.

PubMed ID: 20097625

DOI: 10.1016/j.dnarep.2009.12.020

PubMed ID: 20042607

Title: SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages.

PubMed ID: 20042607

DOI: 10.1074/jbc.m109.038604

PubMed ID: 20100829

Title: SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60.

PubMed ID: 20100829

DOI: 10.1074/jbc.m109.087585

PubMed ID: 20167603

Title: DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.

PubMed ID: 20167603

DOI: 10.1074/jbc.m110.102574

PubMed ID: 20817729

Title: SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism.

PubMed ID: 20817729

DOI: 10.1074/jbc.m110.122978

PubMed ID: 20620956

Title: Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha.

PubMed ID: 20620956

DOI: 10.1016/j.molcel.2010.05.023

PubMed ID: 20670893

Title: SIRT1 regulates UV-induced DNA repair through deacetylating XPA.

PubMed ID: 20670893

DOI: 10.1016/j.molcel.2010.07.006

PubMed ID: 19934257

Title: SIRT1 deacetylates APE1 and regulates cellular base excision repair.

PubMed ID: 19934257

DOI: 10.1093/nar/gkp1039

PubMed ID: 20375098

Title: Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation.

PubMed ID: 20375098

DOI: 10.1093/nar/gkq227

PubMed ID: 20169165

Title: SIRT1 negatively regulates the mammalian target of rapamycin.

PubMed ID: 20169165

DOI: 10.1371/journal.pone.0009199

PubMed ID: 20975832

Title: SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.

PubMed ID: 20975832

DOI: 10.1371/journal.pone.0013502

PubMed ID: 21149730

Title: Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C.

PubMed ID: 21149730

DOI: 10.1073/pnas.1010377108

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21701047

Title: SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.

PubMed ID: 21701047

DOI: 10.18632/aging.100339

PubMed ID: 21305533

Title: Tumor necrosis factor alpha-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes.

PubMed ID: 21305533

DOI: 10.1002/art.30279

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 20955178

Title: Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation.

PubMed ID: 20955178

DOI: 10.1042/bj20101293

PubMed ID: 21555002

Title: EVI1 up-regulates the stress responsive gene SIRT1 which triggers deacetylation and degradation of EVI1.

PubMed ID: 21555002

DOI: 10.1016/j.bbagrm.2011.04.007

PubMed ID: 21933665

Title: Energy sensing factors PGC-1alpha and SIRT1 modulate PXR expression and function.

PubMed ID: 21933665

DOI: 10.1016/j.bcp.2011.09.006

PubMed ID: 21807113

Title: Sirt1 deacetylates c-Myc and promotes c-Myc/Max association.

PubMed ID: 21807113

DOI: 10.1016/j.biocel.2011.07.006

PubMed ID: 21212262

Title: MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation.

PubMed ID: 21212262

DOI: 10.1074/jbc.m110.182543

PubMed ID: 21471201

Title: Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent Inhibition of sirtuin 1.

PubMed ID: 21471201

DOI: 10.1074/jbc.m111.240598

PubMed ID: 21504832

Title: Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection.

PubMed ID: 21504832

DOI: 10.1016/j.molcel.2011.02.034

PubMed ID: 21947282

Title: SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities.

PubMed ID: 21947282

DOI: 10.1128/mcb.06147-11

PubMed ID: 21698133

Title: SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability.

PubMed ID: 21698133

DOI: 10.1371/journal.pgen.1002135

PubMed ID: 21909281

Title: The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO.

PubMed ID: 21909281

DOI: 10.1371/journal.pgen.1002235

PubMed ID: 21245319

Title: Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1).

PubMed ID: 21245319

DOI: 10.1073/pnas.1019619108

PubMed ID: 21775285

Title: The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy.

PubMed ID: 21775285

DOI: 10.1126/scisignal.2001465

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 21987377

Title: 75kDa SirT1 blocks TNFalpha-mediated apoptosis in human osteoarthritic chondrocytes.

PubMed ID: 21987377

DOI: 10.1002/art.33407

PubMed ID: 21890893

Title: SIRT1 links CIITA deacetylation to MHC II activation.

PubMed ID: 21890893

DOI: 10.1093/nar/gkr651

PubMed ID: 22274616

Title: PML regulates PER2 nuclear localization and circadian function.

PubMed ID: 22274616

DOI: 10.1038/emboj.2012.1

PubMed ID: 23142079

Title: The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.

PubMed ID: 23142079

DOI: 10.1016/j.molcel.2012.09.030

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 21841822

Title: Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation.

PubMed ID: 21841822

DOI: 10.1038/onc.2011.347

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23352644

Title: Deleted in breast cancer 1 (DBC1) deficiency results in apoptosis of breast cancer cells through impaired responses to UV-induced DNA damage.

PubMed ID: 23352644

DOI: 10.1016/j.canlet.2013.01.026

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24043310

Title: SIRT4 represses peroxisome proliferator-activated receptor alpha activity to suppress hepatic fat oxidation.

PubMed ID: 24043310

DOI: 10.1128/mcb.00087-13

PubMed ID: 24415752

Title: Deleted in breast cancer 1 (DBC1) protein regulates hepatic gluconeogenesis.

PubMed ID: 24415752

DOI: 10.1074/jbc.m113.512913

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25406032

Title: Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage.

PubMed ID: 25406032

DOI: 10.1038/ncomms6483

PubMed ID: 25361978

Title: Chk2 and REGgamma-dependent DBC1 regulation in DNA damage induced apoptosis.

PubMed ID: 25361978

DOI: 10.1093/nar/gku1065

PubMed ID: 24824780

Title: MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm.

PubMed ID: 24824780

DOI: 10.1002/ijc.28967

PubMed ID: 25661920

Title: CCAR2 negatively regulates nuclear receptor LXRalpha by competing with SIRT1 deacetylase.

PubMed ID: 25661920

DOI: 10.1016/j.jsbmb.2015.02.001

PubMed ID: 28497810

Title: Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription.

PubMed ID: 28497810

DOI: 10.1038/cr.2017.68

PubMed ID: 29656858

Title: A recurrent de novo PACS2 heterozygous missense variant causes neonatal-onset developmental epileptic encephalopathy, facial dysmorphism, and cerebellar dysgenesis.

PubMed ID: 29656858

DOI: 10.1016/j.ajhg.2018.03.005

Sequence Information:

  • Length: 747
  • Mass: 81681
  • Checksum: 2D3BEA6D73DA229F
  • Sequence:
  • MADEAALALQ PGGSPSAAGA DREAASSPAG EPLRKRPRRD GPGLERSPGE PGGAAPEREV 
    PAAARGCPGA AAAALWREAE AEAAAAGGEQ EAQATAAAGE GDNGPGLQGP SREPPLADNL 
    YDEDDDDEGE EEEEAAAAAI GYRDNLLFGD EIITNGFHSC ESDEEDRASH ASSSDWTPRP 
    RIGPYTFVQQ HLMIGTDPRT ILKDLLPETI PPPELDDMTL WQIVINILSE PPKRKKRKDI 
    NTIEDAVKLL QECKKIIVLT GAGVSVSCGI PDFRSRDGIY ARLAVDFPDL PDPQAMFDIE 
    YFRKDPRPFF KFAKEIYPGQ FQPSLCHKFI ALSDKEGKLL RNYTQNIDTL EQVAGIQRII 
    QCHGSFATAS CLICKYKVDC EAVRGDIFNQ VVPRCPRCPA DEPLAIMKPE IVFFGENLPE 
    QFHRAMKYDK DEVDLLIVIG SSLKVRPVAL IPSSIPHEVP QILINREPLP HLHFDVELLG 
    DCDVIINELC HRLGGEYAKL CCNPVKLSEI TEKPPRTQKE LAYLSELPPT PLHVSEDSSS 
    PERTSPPDSS VIVTLLDQAA KSNDDLDVSE SKGCMEEKPQ EVQTSRNVES IAEQMENPDL 
    KNVGSSTGEK NERTSVAGTV RKCWPNRVAK EQISRRLDGN QYLFLPPNRY IFHGAEVYSD 
    SEDDVLSSSS CGSNSDSGTC QSPSLEEPME DESEIEEFYN GLEDEPDVPE RAGGAGFGTD 
    GDDQEAINEA ISVKQEVTDM NYPSNKS

Genular Protein ID: 2731210439

Symbol: A8K128_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 555
  • Mass: 61957
  • Checksum: AE0057C17E4BBB1E
  • Sequence:
  • MIGTDPRTIL KDLLPETIPP PELDDMTLWQ IVINILSEPP KRKKRKDINT IEDAVKLLQE 
    CKKIIVLTGA GVSVSCGIPD FRSRDGIYAR LAVDFPDLPD PQAMFDIEYF RKDPRPFFKF 
    AKEIYPGQFQ PSLCHKFIAL SDKEGKLLRN YTQNIDTLEQ VAGIQRIIQC HGSFATASCL 
    ICKYKVDCEA VRGDIFNQVV PRCPRCPADE PLAIMKPEIV FFGENLPEQF HRAMKYDKDE 
    VDLLIVIGSS LKVRPVALIP SSIPHEVPQI LINREPLPHL HFDVELLGDC DVIINELCHR 
    LGGEYAKLCC NPVKLSEITE KPPRTQKELA YLSELPPTPL HVSEDSSSPE RTSPPDSSVI 
    VTLLDQAAKS NDDLDVSESK GCMEEKPQEV QTSRNVESIA EQMENPDLKN VGSSTGEKNE 
    RTSVAGTVRK CWPNRVAKEQ ISRRLDGNQY LFLPPNRYIF HGAEVYSDSE DDVLSSSSCG 
    SNSDSGTCQS PSLEEPMEDE SEIEEFYNGL EDEPDVPERA GGAGFGTDGD DQEAINEAIS 
    VKQEVTDMNY PSNKS

Genular Protein ID: 1653852372

Symbol: E9PC49_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 452
  • Mass: 50497
  • Checksum: DADC9A384CCCDD9B
  • Sequence:
  • MFDIEYFRKD PRPFFKFAKE IYPGQFQPSL CHKFIALSDK EGKLLRNYTQ NIDTLEQVAG 
    IQRIIQCHGS FATASCLICK YKVDCEAVRG DIFNQVVPRC PRCPADEPLA IMKPEIVFFG 
    ENLPEQFHRA MKYDKDEVDL LIVIGSSLKV RPVALIPSSI PHEVPQILIN REPLPHLHFD 
    VELLGDCDVI INELCHRLGG EYAKLCCNPV KLSEITEKPP RTQKELAYLS ELPPTPLHVS 
    EDSSSPERTS PPDSSVIVTL LDQAAKSNDD LDVSESKGCM EEKPQEVQTS RNVESIAEQM 
    ENPDLKNVGS STGEKNERTS VAGTVRKCWP NRVAKEQISR RLDGNQYLFL PPNRYIFHGA 
    EVYSDSEDDV LSSSSCGSNS DSGTCQSPSL EEPMEDESEI EEFYNGLEDE PDVPERAGGA 
    GFGTDGDDQE AINEAISVKQ EVTDMNYPSN KS

Genular Protein ID: 2970070924

Symbol: B0QZ35_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 444
  • Mass: 49238
  • Checksum: ED74C7BC5111036D
  • Sequence:
  • MCLCSGRKTI LEIYPGQFQP SLCHKFIALS DKEGKLLRNY TQNIDTLEQV AGIQRIIQCH 
    GSFATASCLI CKYKVDCEAV RGDIFNQVVP RCPRCPADEP LAIMKPEIVF FGENLPEQFH 
    RAMKYDKDEV DLLIVIGSSL KVRPVALIPS SIPHEVPQIL INREPLPHLH FDVELLGDCD 
    VIINELCHRL GGEYAKLCCN PVKLSEITEK PPRTQKELAY LSELPPTPLH VSEDSSSPER 
    TSPPDSSVIV TLLDQAAKSN DDLDVSESKG CMEEKPQEVQ TSRNVESIAE QMENPDLKNV 
    GSSTGEKNER TSVAGTVRKC WPNRVAKEQI SRRLDGNQYL FLPPNRYIFH GAEVYSDSED 
    DVLSSSSCGS NSDSGTCQSP SLEEPMEDES EIEEFYNGLE DEPDVPERAG GAGFGTDGDD 
    QEAINEAISV KQEVTDMNYP SNKS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.