Details for: MLYCD

Gene ID: 23417

Symbol: MLYCD

Ensembl ID: ENSG00000103150

Description: malonyl-CoA decarboxylase

Associated with

Other Information

Genular Protein ID: 263023816

Symbol: DCMC_HUMAN

Name: N/A

UniProtKB Accession Codes:

O95822 Q9UNU5 Q9Y3F2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EC 1 EMBL 6 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 18 Gene3D 2 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 2 SABIO-RK 1 SMR 1 STRING 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10417274

Title: The molecular basis of malonyl-CoA decarboxylase deficiency.

PubMed ID: 10417274

DOI: 10.1086/302492

PubMed ID: 10455107

Title: MCD encodes peroxisomal and cytoplasmic forms of malonyl-CoA decarboxylase and is mutated in malonyl-CoA decarboxylase deficiency.

PubMed ID: 10455107

DOI: 10.1074/jbc.274.35.24461

PubMed ID: 9869665

Title: Cloning and mutational analysis of human malonyl-coenzyme A decarboxylase.

PubMed ID: 9869665

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15003260

Title: Expression, purification, and characterization of human malonyl-CoA decarboxylase.

PubMed ID: 15003260

DOI: 10.1016/j.pep.2003.11.023

PubMed ID: 18314420

Title: Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle.

PubMed ID: 18314420

DOI: 10.2337/db07-0583

PubMed ID: 20178365

Title: A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities.

PubMed ID: 20178365

DOI: 10.1021/ja9109049

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 23482565

Title: Structural asymmetry and disulphide bridges among subunits modulate the activity of human Malonyl-CoA Decarboxylase.

PubMed ID: 23482565

DOI: 10.1074/jbc.m112.443846

PubMed ID: 23791943

Title: Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations.

PubMed ID: 23791943

DOI: 10.1016/j.str.2013.05.001

Sequence Information:

  • Length: 493
  • Mass: 55003
  • Checksum: 8F061CA38908E8FC
  • Sequence:
    • MRGFGPGLTA RRLLPLRLPP RPPGPRLASG QAAGALERAM DELLRRAVPP TPAYELREKT 
PAPAEGQCAD FVSFYGGLAE TAQRAELLGR LARGFGVDHG QVAEQSAGVL HLRQQQREAA 
VLLQAEDRLR YALVPRYRGL FHHISKLDGG VRFLVQLRAD LLEAQALKLV EGPDVREMNG 
VLKGMLSEWF SSGFLNLERV TWHSPCEVLQ KISEAEAVHP VKNWMDMKRR VGPYRRCYFF 
SHCSTPGEPL VVLHVALTGD ISSNIQAIVK EHPPSETEEK NKITAAIFYS ISLTQQGLQG 
VELGTFLIKR VVKELQREFP HLGVFSSLSP IPGFTKWLLG LLNSQTKEHG RNELFTDSEC 
KEISEITGGP INETLKLLLS SSEWVQSEKL VRALQTPLMR LCAWYLYGEK HRGYALNPVA 
NFHLQNGAVL WRINWMADVS LRGITGSCGL MANYRYFLEE TGPNSTSYLG SKIIKASEQV 
LSLVAQFQKN SKL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.