Details for: HARS2

Gene ID: 23438

Symbol: HARS2

Ensembl ID: ENSG00000112855

Description: histidyl-tRNA synthetase 2, mitochondrial

Associated with

Other Information

Genular Protein ID: 3817950628

Symbol: SYHM_HUMAN

Name: Histidine--tRNA ligase, mitochondrial

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7755634

Title: A novel gene oriented in a head-to-head configuration with the human histidyl-tRNA synthetase (HRS) gene encodes an mRNA that predicts a polypeptide homologous to HRS.

PubMed ID: 7755634

DOI: 10.1006/bbrc.1995.1696

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 21464306

Title: Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome.

PubMed ID: 21464306

DOI: 10.1073/pnas.1103471108

PubMed ID: 31449985

Title: Novel HARS2 missense variants identified in individuals with sensorineural hearing impairment and Perrault syndrome.

PubMed ID: 31449985

DOI: 10.1016/j.ejmg.2019.103733

Sequence Information:

  • Length: 506
  • Mass: 56888
  • Checksum: E1CE879837AE26E7
  • Sequence:
  • MPLLGLLPRR AWASLLSQLL RPPCASCTGA VRCQSQVAEA VLTSQLKAHQ EKPNFIIKTP 
    KGTRDLSPQH MVVREKILDL VISCFKRHGA KGMDTPAFEL KETLTEKYGE DSGLMYDLKD 
    QGGELLSLRY DLTVPFARYL AMNKVKKMKR YHVGKVWRRE SPTIVQGRYR EFCQCDFDIA 
    GQFDPMIPDA ECLKIMCEIL SGLQLGDFLI KVNDRRIVDG MFAVCGVPES KFRAICSSID 
    KLDKMAWKDV RHEMVVKKGL APEVADRIGD YVQCHGGVSL VEQMFQDPRL SQNKQALEGL 
    GDLKLLFEYL TLFGIADKIS FDLSLARGLD YYTGVIYEAV LLQTPTQAGE EPLNVGSVAA 
    GGRYDGLVGM FDPKGHKVPC VGLSIGVERI FYIVEQRMKT KGEKVRTTET QVFVATPQKN 
    FLQERLKLIA ELWDSGIKAE MLYKNNPKLL TQLHYCESTG IPLVVIIGEQ ELKEGVIKIR 
    SVASREEVAI KRENFVAEIQ KRLSES

Genular Protein ID: 2353386120

Symbol: B4DDN8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 362
  • Mass: 40449
  • Checksum: 2644BD420F0E6500
  • Sequence:
  • MVVREKILDL VISCFKRHGA RGMDTPAFEL KDFDIAGQFD PMIPDAECLK IMCEILSGLQ 
    LGDFLIKVND RRIVDGMFAV CGVPESKFRA IGSSIDKLDK MAWKDVRHEM VVKKGLAPEV 
    ADRIGDYVQC HGGVSLVEQM FQDPRLSQNK QALEGLGDLK LLFEYLTLFG IADKISFDLS 
    LARGLDYYTG VIYEAVLLQT PTQAGEEPLN VGSVAAGGRY DGLVGMFDPK GHKVPCVGLS 
    IGVERIFYIV EQRMKTKGEK VRTTETQVFV ATPQKNFLQE RLKLIAELWD SGIKAEMLYK 
    NNPKLLTQLH YCESTGIPLV VIIGEQELKE GVIKIRSVAS REEVAIKREN FVAEIQKRLS 
    ES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.