SLC44A1 | ENSG00000070214 | NCBI 23446

Details for: SLC44A1

Gene ID: 23446

Symbol: SLC44A1

Ensembl ID: ENSG00000070214

Description: solute carrier family 44 member 1

Associated with

Choline catabolism
(R-HSA-6798163)
Glycerophospholipid biosynthesis
(R-HSA-1483206)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Metabolism of lipids
(R-HSA-556833)
Phospholipid metabolism
(R-HSA-1483257)
Slc-mediated transmembrane transport
(R-HSA-425407)
Synthesis of pc
(R-HSA-1483191)
Transport of bile salts and organic acids, metal ions and amine compounds
(R-HSA-425366)
Transport of small molecules
(R-HSA-382551)
Antiporter activity
(GO:0015297)
Choline catabolic process
(GO:0042426)
Choline transmembrane transporter activity
(GO:0015220)
Choline transport
(GO:0015871)
Cytosol
(GO:0005829)
Ethanolamine transmembrane transporter activity
(GO:0034228)
Ethanolamine transport
(GO:0034229)
Extracellular exosome
(GO:0070062)
Membrane
(GO:0016020)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Nucleoplasm
(GO:0005654)
Phosphatidylcholine biosynthetic process
(GO:0006656)
Plasma membrane
(GO:0005886)
Transmembrane transport
(GO:0055085)
Transport across blood-brain barrier
(GO:0150104)

Other Information

Proteins

CDw92

Genular Protein ID: 1102346502

Symbol: CTL1_HUMAN

Name: CDw92

UniProtKB Accession Codes:

Q8WWI5 A6NLZ9 Q5VUB3 Q8WVB0 Q96KU3 Q9NY69

Database IDs:

Citations:

PubMed ID: 10677542

Title: An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins.

PubMed ID: 10677542

DOI: 10.1073/pnas.030339697

PubMed ID: 11698453

Title: Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells.

PubMed ID: 11698453

DOI: 10.4049/jimmunol.167.10.5795

PubMed ID: 15715662

Title: Molecular characterization of the family of choline transporter-like proteins and their splice variants.

PubMed ID: 15715662

DOI: 10.1111/j.1471-4159.2004.02962.x

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19357133

Title: The solute carrier 44A1 is a mitochondrial protein and mediates choline transport.

PubMed ID: 19357133

DOI: 10.1096/fj.08-121491

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23651124

Title: Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis.

PubMed ID: 23651124

DOI: 10.1111/jnc.12298

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 33789160

Title: Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters.

PubMed ID: 33789160

DOI: 10.1016/j.jbc.2021.100604

PubMed ID: 31855247

Title: Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration.

PubMed ID: 31855247

DOI: 10.1093/brain/awz376

Sequence Information:

Length: 657
Mass: 73302
Checksum: 10D70CAB8E33E3AC
Sequence:

MGCCSSASSA AQSSKREWKP LEDRSCTDIP WLLLFILFCI GMGFICGFSI ATGAAARLVS 
GYDSYGNICG QKNTKLEAIP NSGMDHTQRK YVFFLDPCNL DLINRKIKSV ALCVAACPRQ 
ELKTLSDVQK FAEINGSALC SYNLKPSEYT TSPKSSVLCP KLPVPASAPI PFFHRCAPVN 
ISCYAKFAEA LITFVSDNSV LHRLISGVMT SKEIILGLCL LSLVLSMILM VIIRYISRVL 
VWILTILVIL GSLGGTGVLW WLYAKQRRSP KETVTPEQLQ IAEDNLRALL IYAISATVFT 
VILFLIMLVM RKRVALTIAL FHVAGKVFIH LPLLVFQPFW TFFALVLFWV YWIMTLLFLG 
TTGSPVQNEQ GFVEFKISGP LQYMWWYHVV GLIWISEFIL ACQQMTVAGA VVTYYFTRDK 
RNLPFTPILA SVNRLIRYHL GTVAKGSFII TLVKIPRMIL MYIHSQLKGK ENACARCVLK 
SCICCLWCLE KCLNYLNQNA YTATAINSTN FCTSAKDAFV ILVENALRVA TINTVGDFML 
FLGKVLIVCS TGLAGIMLLN YQQDYTVWVL PLIIVCLFAF LVAHCFLSIY EMVVDVLFLC 
FAIDTKYNDG SPGREFYMDK VLMEFVENSR KAMKEAGKGG VADSRELKPM ASGASSA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SLC44A1

Associated with

Other Information

An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins. PubMed ID: 10677542

Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells. PubMed ID: 11698453

Molecular characterization of the family of choline transporter-like proteins and their splice variants. PubMed ID: 15715662

DNA sequence and analysis of human chromosome 9. PubMed ID: 15164053

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

The solute carrier 44A1 is a mitochondrial protein and mediates choline transport. PubMed ID: 19357133

Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features. PubMed ID: 22223895

Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis. PubMed ID: 23651124

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters. PubMed ID: 33789160

Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration. PubMed ID: 31855247