Details for: ICMT

Gene ID: 23463

Symbol: ICMT

Ensembl ID: ENSG00000116237

Description: isoprenylcysteine carboxyl methyltransferase

Associated with

Other Information

Genular Protein ID: 302795174

Symbol: ICMT_HUMAN

Name: Protein-S-isoprenylcysteine O-methyltransferase

UniProtKB Accession Codes:

O60725 Q6FHT0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 9 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 6 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 3 SABIO-RK 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9614111

Title: Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum.

PubMed ID: 9614111

DOI: 10.1074/jbc.273.24.15030

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10649571

Title: Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1.

PubMed ID: 10649571

DOI: 10.1038/72101

PubMed ID: 19158273

Title: Topology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe.

PubMed ID: 19158273

DOI: 10.1128/mcb.01719-08

Sequence Information:

  • Length: 284
  • Mass: 31938
  • Checksum: C86741B13ACA611C
  • Sequence:
    • MAGCAARAPP GSEARLSLAT FLLGASVLAL PLLTRAGLQG RTGLALYVAG LNALLLLLYR 
PPRYQIAIRA CFLGFVFGCG TLLSFSQSSW SHFGWYMCSL SLFHYSEYLV TAVNNPKSLS 
LDSFLLNHSL EYTVAALSSW LEFTLENIFW PELKQITWLS VTGLLMVVFG ECLRKAAMFT 
AGSNFNHVVQ NEKSDTHTLV TSGVYAWFRH PSYVGWFYWS IGTQVMLCNP ICGVSYALTV 
WRFFRDRTEE EEISLIHFFG EEYLEYKKRV PTGLPFIKGV KVDL

Genular Protein ID: 905003603

Symbol: B3KS61_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KS61

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 4 DNASU 1 EC 1 EMBL 2 GO 3 Gene3D 1 GenomeRNAi 1 InterPro 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 1 ProteomicsDB 1 RefSeq 1 Rhea 3 RuleBase 1 SMR 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 188
  • Mass: 21735
  • Checksum: 8D226E6C25622EF1
  • Sequence:
    • MCSLSLFHYS EYLVTAVNNP KSLSLDSFLL NHSLEYTVAA LSSWLEFTLE NIFWPELKQI 
TWLSVTGLLM VVFGECLRKA AMFTAGSNFN HVVQNEKSDT HTLVTSGVYA WFRHPSYVGW 
FYWSIGTQVM LCNPICGVSY ALTVWRFFRD RTEEEEISLI HFFGEEYLEY KKRVPTGLPF 
IKGVKVDL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.