HAAO | ENSG00000162882 | NCBI 23498

Details for: HAAO

Gene ID: 23498

Symbol: HAAO

Ensembl ID: ENSG00000162882

Description: 3-hydroxyanthranilate 3,4-dioxygenase

Associated with

Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Tryptophan catabolism
(R-HSA-71240)
'de novo' nad biosynthetic process from tryptophan
(GO:0034354)
3-hydroxyanthranilate 3,4-dioxygenase activity
(GO:0000334)
Anthranilate metabolic process
(GO:0043420)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Electron transfer activity
(GO:0009055)
Electron transport chain
(GO:0022900)
Ferrous iron binding
(GO:0008198)
Nad biosynthetic process
(GO:0009435)
Neuron cellular homeostasis
(GO:0070050)
Protein binding
(GO:0005515)
Quinolinate biosynthetic process
(GO:0019805)
Quinolinate metabolic process
(GO:0046874)
Response to cadmium ion
(GO:0046686)
Response to zinc ion
(GO:0010043)
Tryptophan catabolic process
(GO:0006569)

Other Information

Proteins

3HAO_HUMAN

Genular Protein ID: 2864694601

Symbol: 3HAO_HUMAN

Name: N/A

UniProtKB Accession Codes:

P46952 A6NE56 B4DIN2 Q53QZ7 Q8N6N9

Database IDs:

Citations:

PubMed ID: 7514594

Title: Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase.

PubMed ID: 7514594

DOI: 10.1016/s0021-9258(17)36717-0

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28792876

Title: NAD deficiency, congenital malformations, and niacin supplementation.

PubMed ID: 28792876

DOI: 10.1056/nejmoa1616361

PubMed ID: 28375145

Title: Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site.

PubMed ID: 28375145

DOI: 10.1107/s2059798317002029

Sequence Information:

Length: 286
Mass: 32556
Checksum: 4DA6AC20FC6EC885
Sequence:

MERRLGVRAW VKENRGSFQP PVCNKLMHQE QLKVMFIGGP NTRKDYHIEE GEEVFYQLEG 
DMVLRVLEQG KHRDVVIRQG EIFLLPARVP HSPQRFANTV GLVVERRRLE TELDGLRYYV 
GDTMDVLFEK WFYCKDLGTQ LAPIIQEFFS SEQYRTGKPI PDQLLKEPPF PLSTRSIMEP 
MSLDAWLDSH HRELQAGTPL SLFGDTYETQ VIAYGQGSSE GLRQNVDVWL WQLEGSSVVT 
MGGRRLSLAP DDSLLVLAGT SYAWERTQGS VALSVTQDPA CKKPLG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: HAAO

Associated with

Other Information

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase. PubMed ID: 7514594

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Generation and annotation of the DNA sequences of human chromosomes 2 and 4. PubMed ID: 15815621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

NAD deficiency, congenital malformations, and niacin supplementation. PubMed ID: 28792876

Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site. PubMed ID: 28375145