Details for: SPIDR

Gene ID: 23514

Symbol: SPIDR

Ensembl ID: ENSG00000164808

Description: scaffold protein involved in DNA repair

Associated with

Other Information

Genular Protein ID: 1285234921

Symbol: SPIDR_HUMAN

Name: DNA repair-scaffolding protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8590280

Title: Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 8590280

DOI: 10.1093/dnares/2.4.167

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15502879

Title: Gene expression profile in interleukin-4-stimulated human vascular endothelial cells.

PubMed ID: 15502879

DOI: 10.2119/2004-00024.lee

PubMed ID: 15858003

Title: Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by severe acute respiratory syndrome coronavirus and human coronavirus 229E.

PubMed ID: 15858003

DOI: 10.1128/jvi.79.10.6180-6193.2005

PubMed ID: 23754376

Title: FIGNL1-containing protein complex is required for efficient homologous recombination repair.

PubMed ID: 23754376

DOI: 10.1073/pnas.1220662110

PubMed ID: 23509288

Title: Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair.

PubMed ID: 23509288

DOI: 10.1073/pnas.1220921110

PubMed ID: 27967308

Title: A Biallelic Mutation in the Homologous Recombination Repair Gene SPIDR Is Associated With Human Gonadal Dysgenesis.

PubMed ID: 27967308

DOI: 10.1210/jc.2016-2714

PubMed ID: 34697795

Title: A SPIDR homozygous nonsense pathogenic variant in isolated primary ovarian insufficiency with chromosomal instability.

PubMed ID: 34697795

DOI: 10.1111/cge.14080

Sequence Information:

  • Length: 915
  • Mass: 100316
  • Checksum: DA35068B5849135D
  • Sequence:
  • MPRGSRARGS KRKRSWNTEC PSFPGERPLQ VRRAGLRTAG AAASLSEAWL RCGEGFQNTS 
    GNPSLTAEEK TITEKHLELC PRPKQETTTS KSTSGLTDIT WSSSGSDLSD EDKTLSQLQR 
    DELQFIDWEI DSDRAEASDC DEFEDDEGAV EISDCASCAS NQSLTSDEKL SELPKPSSIE 
    ILEYSSDSEK EDDLENVLLI DSESPHKYHV QFASDARQIM ERLIDPRTKS TETILHTPQK 
    PTAKFPRTPE NSAKKKLLRG GLAERLNGLQ NRERSAISLW RHQCISYQKT LSGRKSGVLT 
    VKILELHEEC AMQVAMCEQL LGSPATSSSQ SVAPRPGAGL KVLFTKETAG YLRGRPQDTV 
    RIFPPWQKLI IPSGSCPVIL NTYFCEKVVA KEDSEKTCEV YCPDIPLPRR SISLAQMFVI 
    KGLTNNSPEI QVVCSGVATT GTAWTHGHKE AKQRIPTSTP LRDSLLDVVE SQGAASWPGA 
    GVRVVVQRVY SLPSRDSTRG QQGASSGHTD PAGTRACLLV QDACGMFGEV HLEFTMSKAR 
    QLEGKSCSLV GMKVLQKVTR GRTAGIFSLI DTLWPPAIPL KTPGRDQPCE EIKTHLPPPA 
    LCYILTAHPN LGQIDIIDED PIYKLYQPPV TRCLRDILQM NDLGTRCSFY ATVIYQKPQL 
    KSLLLLEQRE IWLLVTDVTL QTKEERDPRL PKTLLVYVAP LCVLGSEVLE ALAGAAPHSL 
    FFKDALRDQG RIVCAERTVL LLQKPLLSVV SGASSCELPG PVMLDSLDSA TPVNSICSVQ 
    GTVVGVDEST AFSWPVCDMC GNGRLEQRPE DRGAFSCGDC SRVVTSPVLK RHLQVFLDCR 
    SRPQCRVKVK LLQRSISSLL RFAAGEDGSY EVKSVLGKEV GLLNCFVQSV TAHPTSCIGL 
    EEIELLSAGG ASAEH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.