Details for: MORC3

Gene ID: 23515

Symbol: MORC3

Ensembl ID: ENSG00000159256

Description: MORC family CW-type zinc finger 3

Associated with

Other Information

Genular Protein ID: 542940117

Symbol: MORC3_HUMAN

Name: MORC family CW-type zinc finger protein 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8590280

Title: Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 8590280

DOI: 10.1093/dnares/2.4.167

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 11927593

Title: The newly identified human nuclear protein NXP-2 possesses three distinct domains, the nuclear matrix-binding, RNA-binding, and coiled-coil domains.

PubMed ID: 11927593

DOI: 10.1074/jbc.m201440200

PubMed ID: 17332504

Title: Dynamic regulation of p53 subnuclear localization and senescence by MORC3.

PubMed ID: 17332504

DOI: 10.1091/mbc.e06-08-0747

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20501696

Title: Two-step colocalization of MORC3 with PML nuclear bodies.

PubMed ID: 20501696

DOI: 10.1242/jcs.063586

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 26202233

Title: The Cellular Factor NXP2/MORC3 Is a Positive Regulator of Influenza Virus Multiplication.

PubMed ID: 26202233

DOI: 10.1128/jvi.01530-15

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 27440897

Title: MORC3, a Component of PML Nuclear Bodies, Has a Role in Restricting Herpes Simplex Virus 1 and Human Cytomegalovirus.

PubMed ID: 27440897

DOI: 10.1128/jvi.00621-16

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 34759314

Title: Self-guarding of MORC3 enables virulence factor-triggered immunity.

PubMed ID: 34759314

DOI: 10.1038/s41586-021-04054-5

PubMed ID: 26933034

Title: Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins.

PubMed ID: 26933034

DOI: 10.1074/jbc.m116.718973

PubMed ID: 30850548

Title: Mechanism for autoinhibition and activation of the MORC3 ATPase.

PubMed ID: 30850548

DOI: 10.1073/pnas.1819524116

PubMed ID: 31006586

Title: MORC3 Is a Target of the Influenza A Viral Protein NS1.

PubMed ID: 31006586

DOI: 10.1016/j.str.2019.03.015

Sequence Information:

  • Length: 939
  • Mass: 107113
  • Checksum: 7DF0EC31936BF5FF
  • Sequence:
  • MAAQPPRGIR LSALCPKFLH TNSTSHTWPF SAVAELIDNA YDPDVNAKQI WIDKTVINDH 
    ICLTFTDNGN GMTSDKLHKM LSFGFSDKVT MNGHVPVGLY GNGFKSGSMR LGKDAIVFTK 
    NGESMSVGLL SQTYLEVIKA EHVVVPIVAF NKHRQMINLA ESKASLAAIL EHSLFSTEQK 
    LLAELDAIIG KKGTRIIIWN LRSYKNATEF DFEKDKYDIR IPEDLDEITG KKGYKKQERM 
    DQIAPESDYS LRAYCSILYL KPRMQIILRG QKVKTQLVSK SLAYIERDVY RPKFLSKTVR 
    ITFGFNCRNK DHYGIMMYHR NRLIKAYEKV GCQLRANNMG VGVVGIIECN FLKPTHNKQD 
    FDYTNEYRLT ITALGEKLND YWNEMKVKKN TEYPLNLPVE DIQKRPDQTW VQCDACLKWR 
    KLPDGMDQLP EKWYCSNNPD PQFRNCEVPE EPEDEDLVHP TYEKTYKKTN KEKFRIRQPE 
    MIPRINAELL FRPTALSTPS FSSPKESVPR RHLSEGTNSY ATRLLNNHQV PPQSEPESNS 
    LKRRLSTRSS ILNAKNRRLS SQFENSVYKG DDDDEDVIIL EENSTPKPAV DHDIDMKSEQ 
    SHVEQGGVQV EFVGDSEPCG QTGSTSTSSS RCDQGNTAAT QTEVPSLVVK KEETVEDEID 
    VRNDAVILPS CVEAEAKIHE TQETTDKSAD DAGCQLQELR NQLLLVTEEK ENYKRQCHMF 
    TDQIKVLQQR ILEMNDKYVK KETCHQSTET DAVFLLESIN GKSESPDHMV SQYQQALEEI 
    ERLKKQCSAL QHVKAECSQC SNNESKSEMD EMAVQLDDVF RQLDKCSIER DQYKSEVELL 
    EMEKSQIRSQ CEELKTEVEQ LKSTNQQTAT DVSTSSNIEE SVNHMDGESL KLRSLRVNVG 
    QLLAMIVPDL DLQQVNYDVD VVDEILGQVV EQMSEISST

Genular Protein ID: 385750411

Symbol: Q4VBZ9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 939
  • Mass: 107041
  • Checksum: 2BC5B804C670B365
  • Sequence:
  • MAAQPPRGIR LSALCPKFLH TNSTSHTWPF SAVAELIDNA YDPDVNAKQI WIDKTVINDH 
    ICLTFTDNGN GMTSDKLHKM LSFGFSDKVT MNGHVPVGLY GNGFKSGSMR LGKDAIVFTK 
    NGESMSVGLL SQTYLEVIKA EHVVVPIVAF NKHRQMINLA ESKASLAAIL EHSLFSTEQK 
    LLAELDAIIG KKGTRIIIWN LRSYKNATEF DFEKDKYDIR IPEDLDEITG KKGYKKQERM 
    DQIAPESDYS LRAYCSILYL KPRMQIILRG QKVKTQLVSK SLAYIERDVY RPKFLSKTVR 
    ITFGFNCRNK DHYGIMMYHR NRLIKAYEKV GCQLRANNMG VGVVGIIECN FLKPTHNKQD 
    FDYTNEYRLT ITALGEKLND YWNEMKVKKN TEYPLNLPVE DIQKRPDQTW VQCDACLKWR 
    KLPDGMDQLP EKWYCSNNPD PQFRNCEVPE EPEDEDLVHP TYEKTYKKTN KEKFRIRQPE 
    MIPRINAELL FRPTALSTPS FSSPKESVPR RHLSEGTNSY ATRLLNNHQV PPQSEPESNS 
    LKRRLSTRSS ILNAKNRRLS SQFENSVYKG DDDDGDVIIL EENSTPKPAV DHDIDMKSEQ 
    SHVEQGGVQV EFVGDSEPCG QTGSTSTSSS RCDQGNTAAT QTEVPSLVVK KEETVEDEID 
    VRNDAVILPS CVEAEAKIHE TQETTDKSAD DAGCQLQELR NQLLLVTEEK ENYKRQCHMF 
    TDQIKVLQQR ILEMNDKYVK KETCHQSTET DAVFLLESIN GKSESPDHMV SQYQQALEEI 
    ERLKKQCSAL QHVKAECSQC SNNESKSEMD EMAVQLDDVF RQLDKCSIER DQYKSEVELL 
    EMEKSQIRSQ CEELKTEVEQ LKSTNQQTAT DVSTSSNIEE SVNHMDGESL KLRSLRVNVG 
    QLLAMIVPDL DLQQVNYDVD VVDEILGQVV EQMSEISST

Genular Protein ID: 1333636295

Symbol: B4DHJ4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 868
  • Mass: 99278
  • Checksum: 9210E6F89983E188
  • Sequence:
  • MTSDKLHKML SFGFSDKVTM NGHVPVGLYG NGFKSGSMRL GKDAIVFTKN GESMSVGLLS 
    QTYLEVIKAE HVVVPIVAFN KHRQMINLAE SKASLAAILE HSLFSTEQKL LAELDAIIGK 
    KGTRIIIWNL RSYKNATEFD FEKDKYDIRI PEDLDEITGK KGYKKQERMD QIAPESDYSL 
    RAYCSILYLK PRMQIILRGQ KVKTQLVSKS LAYIERDVYR PKFLSKTVRI TFGFNCRNKD 
    HYGIMMYHRN RLIKAYEKVG CQLRANNMGV GVVGIIECNF LKPTHNKQDF DYTNEYRLTI 
    TALGEKLNDY WNEMKVKKNT EYPLNLPVED IQKRPDQTWV QCDACLKWRK LPDGMDQLPE 
    KWYCSNNPDP QFRNCEVPEE PEDEDLVHPT YEKTYKKTNK EKFRIRQPEM IPRINAELLF 
    RPTALSTPSF SSPKESVPRR HLSEGTNSYA TRLLNNHQVP PQSEPESNSL KRRLSTRSSI 
    LNAKNRRLSS QFENSVYKGD DDDEDVIILE ENSTPKPAVD HDIDMKSEQS HVEQGGVQVE 
    FVGDSEPCGQ TGSTSTSSSR CDQGNTAATQ TEVPSLVVKK EETVEDEIDV RNDAVILPSC 
    VEAEAKIHET QETTDKSADD AGCQLQELRN QLLLVTEEKE NYKRQCHMFT DQIKVLQQRI 
    LEMNDKYVKK ETCHQSTETD AVFLLESING KSESPDHMVS QYQQALEEIE RLKKQCSALQ 
    HVKAECSQCS NNESKSEMDE MAVQLDDVFR QLDKCSIERD QYKSEVELLE MEKSQIRSQC 
    EELKTEVEQL KSTNQQTATD VSTSSNIEES VNHMDGESLK LRSLRVNVGQ LLAMIVPDLD 
    LQQVNYDVDV VDEILGQVVE QMSEISST

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.