Details for: MTREX

Gene ID: 23517

Symbol: MTREX

Ensembl ID: ENSG00000039123

Description: Mtr4 exosome RNA helicase

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 4.41
    Marker Score: 58,614
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 2.72
    Marker Score: 1,321
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.13
    Marker Score: 4,675
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.86
    Marker Score: 27,794
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.86
    Marker Score: 36,926
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.82
    Marker Score: 69,088
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.77
    Marker Score: 13,537
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.73
    Marker Score: 2,154
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.73
    Marker Score: 36,817
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.72
    Marker Score: 6,667
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.71
    Marker Score: 1,885
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.7
    Marker Score: 62,798
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.7
    Marker Score: 992
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.69
    Marker Score: 103,975
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.68
    Marker Score: 15,999
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.68
    Marker Score: 1,928
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.66
    Marker Score: 15,639
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.66
    Marker Score: 6,873
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.63
    Marker Score: 14,004
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.63
    Marker Score: 3,901
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.62
    Marker Score: 6,770
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.6
    Marker Score: 2,149
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.58
    Marker Score: 1,449
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.54
    Marker Score: 451
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.53
    Marker Score: 15,754
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.52
    Marker Score: 2,931
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.52
    Marker Score: 795
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.52
    Marker Score: 1,838
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.45
    Marker Score: 2,237
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.43
    Marker Score: 5,075
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.42
    Marker Score: 410
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.4
    Marker Score: 31,199
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.39
    Marker Score: 830
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.37
    Marker Score: 1,968
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.36
    Marker Score: 1,216
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 1.36
    Marker Score: 912
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.36
    Marker Score: 570
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.29
    Marker Score: 409
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.29
    Marker Score: 1,614
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.28
    Marker Score: 1,384
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 1.28
    Marker Score: 1,599
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.26
    Marker Score: 704
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.26
    Marker Score: 852
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.24
    Marker Score: 393
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.19
    Marker Score: 628
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.19
    Marker Score: 4,835
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.17
    Marker Score: 1,120
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.17
    Marker Score: 321
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.14
    Marker Score: 1,414
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.14
    Marker Score: 329
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.12
    Marker Score: 625
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.11
    Marker Score: 386
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.11
    Marker Score: 2,609
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.09
    Marker Score: 757
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 1.09
    Marker Score: 923
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.08
    Marker Score: 1,136
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.08
    Marker Score: 1,092
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.06
    Marker Score: 1,556
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.04
    Marker Score: 1,103
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.04
    Marker Score: 518
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.03
    Marker Score: 704
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 1.03
    Marker Score: 575
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.03
    Marker Score: 511
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.02
    Marker Score: 15,938
  • Cell Name: neural cell (CL0002319)
    Fold Change: 1.02
    Marker Score: 490
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.01
    Marker Score: 381
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.01
    Marker Score: 776
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.01
    Marker Score: 669
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1
    Marker Score: 1,011
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1
    Marker Score: 202
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,613
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.99
    Marker Score: 47,840
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.99
    Marker Score: 2,065
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.99
    Marker Score: 400
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.99
    Marker Score: 2,814
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,379
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.98
    Marker Score: 4,512
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.97
    Marker Score: 360
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.96
    Marker Score: 530
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.96
    Marker Score: 272
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.95
    Marker Score: 3,517
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.95
    Marker Score: 553
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.95
    Marker Score: 634
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.95
    Marker Score: 1,340
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.95
    Marker Score: 226
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.94
    Marker Score: 320
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,385
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 0.94
    Marker Score: 499
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.94
    Marker Score: 625
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: 0.94
    Marker Score: 281
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 0.93
    Marker Score: 8,110
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.93
    Marker Score: 1,586
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.93
    Marker Score: 230
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.93
    Marker Score: 826
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.93
    Marker Score: 1,002
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.93
    Marker Score: 991
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 0.93
    Marker Score: 2,334
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 476
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 433
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.91
    Marker Score: 214

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **RNA helicase activity:** Mtr4 is equipped with RNA helicase activity, enabling it to unwind RNA double-strand structures, thereby facilitating the processing of RNA molecules. 2. **Exosome complex member:** As a component of the Mtr4 complex, this enzyme collaborates with other exosome subunits to regulate RNA processing in the nucleus and cytosol. 3. **RNA processing:** Mtr4 is involved in the maturation of 5.8S rRNA and the processing of capped intron-containing pre-mRNAs, ensuring the proper regulation of gene expression. 4. **Cell-type specific expression:** Mtr4 is significantly expressed in various cell types, including cardiac muscle cells, astrocytes, and GABAergic cortical interneurons, suggesting its importance in maintaining cellular homeostasis. **Pathways and Functions:** 1. **RNA processing pathways:** Mtr4 is involved in several RNA processing pathways, including the maturation of 5.8S rRNA, the processing of capped intron-containing pre-mRNAs, and the regulation of RNA catabolic processes. 2. **Exosome complex function:** As a member of the Mtr4 complex, this enzyme collaborates with other exosome subunits to regulate RNA processing in the nucleus and cytosol. 3. **DNA damage response:** Mtr4 has been implicated in the regulation of DNA damage response pathways, suggesting its role in maintaining genome integrity. 4. **Nucleolus and nucleoplasm regulation:** Mtr4 is involved in the regulation of nucleolus and nucleoplasm functions, highlighting its importance in maintaining cellular homeostasis. **Clinical Significance:** 1. **Dysregulation in human diseases:** Aberrant expression of Mtr4 has been implicated in various human diseases, including cancer, neurological disorders, and cardiovascular diseases. 2. **Cancer:** Mtr4 has been shown to be overexpressed in several types of cancer, including breast cancer and lung cancer, suggesting its potential as a diagnostic biomarker and therapeutic target. 3. **Neurological disorders:** Mtr4 has been implicated in the regulation of RNA processing in neurological disorders, such as Alzheimer's disease and Parkinson's disease, highlighting its potential as a therapeutic target. 4. **Cardiovascular diseases:** Mtr4 has been shown to be involved in the regulation of RNA processing in cardiac muscle cells, suggesting its potential as a therapeutic target for cardiovascular diseases. In conclusion, the Mtr4 exosome RNA helicase plays a crucial role in RNA processing, particularly in the maturation of 5.8S rRNA and the processing of capped intron-containing pre-mRNAs. Its expression is significantly elevated in various cell types, highlighting its importance in maintaining cellular homeostasis. Aberrant expression of Mtr4 has been implicated in various human diseases, suggesting its potential as a diagnostic biomarker and therapeutic target. Further research is needed to elucidate the mechanisms underlying Mtr4 function and its implications in human diseases.

Genular Protein ID: 1160870178

Symbol: MTREX_HUMAN

Name: ATP-dependent RNA helicase SKIV2L2

UniProtKB Accession Codes:

P42285 Q2M386 Q6MZZ8 Q6P170 Q8N5R0 Q8TAG2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CORUM 1 CTD 1 ChEBI 11 ChEMBL 1 ChiTaRS 1 ComplexPortal 5 DMDM 1 DNASU 1 DisGeNET 1 EC 1 ELM 1 EMBL 8 EMDB 9 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 16 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 22 PDBsum 11 PIRSF 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 2 SAM 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SWISS-2DPAGE 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7584044

Title: Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

PubMed ID: 7584044

DOI: 10.1093/dnares/1.5.223

PubMed ID: 16782053

Title: The AAA-ATPase NVL2 is a component of pre-ribosomal particles that interacts with the DExD/H-box RNA helicase DOB1.

PubMed ID: 16782053

DOI: 10.1016/j.bbrc.2006.06.017

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11719186

Title: AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.

PubMed ID: 11719186

DOI: 10.1016/s0092-8674(01)00578-5

PubMed ID: 12429849

Title: Functional proteomic analysis of human nucleolus.

PubMed ID: 12429849

DOI: 10.1091/mbc.e02-05-0271

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 16263084

Title: Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins.

PubMed ID: 16263084

DOI: 10.1016/j.bbrc.2005.10.090

PubMed ID: 17412707

Title: C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing.

PubMed ID: 17412707

DOI: 10.1093/nar/gkm082

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21855801

Title: Interaction profiling identifies the human nuclear exosome targeting complex.

PubMed ID: 21855801

DOI: 10.1016/j.molcel.2011.06.028

PubMed ID: 22817747

Title: Comparison of the yeast and human nuclear exosome complexes.

PubMed ID: 22817747

DOI: 10.1042/bst20120061

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26166824

Title: NVL2, a nucleolar AAA-ATPase, is associated with the nuclear exosome and is involved in pre-rRNA processing.

PubMed ID: 26166824

DOI: 10.1016/j.bbrc.2015.07.032

PubMed ID: 26456651

Title: AAA-ATPase NVL2 acts on MTR4-exosome complex to dissociate the nucleolar protein WDR74.

PubMed ID: 26456651

DOI: 10.1016/j.bbrc.2015.09.160

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 27871484

Title: Identification of a nuclear exosome decay pathway for processed transcripts.

PubMed ID: 27871484

DOI: 10.1016/j.molcel.2016.09.025

PubMed ID: 27905398

Title: Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.

PubMed ID: 27905398

DOI: 10.1038/ncomms13573

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 29107693

Title: WDR74 participates in an early cleavage of the pre-rRNA processing pathway in cooperation with the nucleolar AAA-ATPase NVL2.

PubMed ID: 29107693

DOI: 10.1016/j.bbrc.2017.10.148

PubMed ID: 29902117

Title: NRDE-2, the human homolog of fission yeast Nrl1, prevents DNA damage accumulation in human cells.

PubMed ID: 29902117

DOI: 10.1080/15476286.2018.1467180

PubMed ID: 30538148

Title: Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.

PubMed ID: 30538148

DOI: 10.1261/rna.069773.118

PubMed ID: 29906447

Title: Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.

PubMed ID: 29906447

DOI: 10.1016/j.cell.2018.05.041

PubMed ID: 29844170

Title: Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex.

PubMed ID: 29844170

DOI: 10.1073/pnas.1803530115

PubMed ID: 30842217

Title: NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.

PubMed ID: 30842217

DOI: 10.1101/gad.322602.118

PubMed ID: 31358741

Title: The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.

PubMed ID: 31358741

DOI: 10.1038/s41467-019-11339-x

Sequence Information:

  • Length: 1042
  • Mass: 117805
  • Checksum: 49F47BEC753FBEE7
  • Sequence:
    • MADAFGDELF SVFEGDSTTA AGTKKDKEKD KGKWKGPPGS ADKAGKRFDG KLQSESTNNG 
KNKRDVDFEG TDEPIFGKKP RIEESITEDL SLADLMPRVK VQSVETVEGC THEVALPAEE 
DYLPLKPRVG KAAKEYPFIL DAFQREAIQC VDNNQSVLVS AHTSAGKTVC AEYAIALALR 
EKQRVIFTSP IKALSNQKYR EMYEEFQDVG LMTGDVTINP TASCLVMTTE ILRSMLYRGS 
EVMREVAWVI FDEIHYMRDS ERGVVWEETI ILLPDNVHYV FLSATIPNAR QFAEWICHLH 
KQPCHVIYTD YRPTPLQHYI FPAGGDGLHL VVDENGDFRE DNFNTAMQVL RDAGDLAKGD 
QKGRKGGTKG PSNVFKIVKM IMERNFQPVI IFSFSKKDCE AYALQMTKLD FNTDEEKKMV 
EEVFSNAIDC LSDEDKKLPQ VEHVLPLLKR GIGIHHGGLL PILKETIEIL FSEGLIKALF 
ATETFAMGIN MPARTVLFTN ARKFDGKDFR WISSGEYIQM SGRAGRRGMD DRGIVILMVD 
EKMSPTIGKQ LLKGSADPLN SAFHLTYNMV LNLLRVEEIN PEYMLEKSFY QFQHYRAIPG 
VVEKVKNSEE QYNKIVIPNE ESVVIYYKIR QQLAKLGKEI EEYIHKPKYC LPFLQPGRLV 
KVKNEGDDFG WGVVVNFSKK SNVKPNSGEL DPLYVVEVLL RCSKESLKNS ATEAAKPAKP 
DEKGEMQVVP VLVHLLSAIS SVRLYIPKDL RPVDNRQSVL KSIQEVQKRF PDGIPLLDPI 
DDMGIQDQGL KKVIQKVEAF EHRMYSHPLH NDPNLETVYT LCEKKAQIAI DIKSAKRELK 
KARTVLQMDE LKCRKRVLRR LGFATSSDVI EMKGRVACEI SSADELLLTE MMFNGLFNDL 
SAEQATALLS CFVFQENSSE MPKLTEQLAG PLRQMQECAK RIAKVSAEAK LEIDEETYLS 
SFKPHLMDVV YTWATGATFA HICKMTDVFE GSIIRCMRRL EELLRQMCQA AKAIGNTELE 
NKFAEGITKI KRDIVFAASL YL

Genular Protein ID: 2387307956

Symbol: Q3MHC9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q3MHC9

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Genevisible 1 GenomeRNAi 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 RefSeq 1 SAM 1 SMR 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 67
  • Mass: 7336
  • Checksum: 9A4E0689BFCACC89
  • Sequence:
    • MADAFGDELF SVFEGDSTTA AGTKKDKEKD KGKWKGPPGS ADKAGKRFDG KLQSESTKKK 
KKKKKKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.