Details for: CABIN1

Gene ID: 23523

Symbol: CABIN1

Ensembl ID: ENSG00000099991

Description: calcineurin binding protein 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 3.08
    Marker Score: 2,466
  • Cell Name: germ cell (CL0000586)
    Fold Change: 2.39
    Marker Score: 4,178
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.74
    Marker Score: 7,104
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.74
    Marker Score: 106,775
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.69
    Marker Score: 16,012
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.68
    Marker Score: 983
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.68
    Marker Score: 979
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.66
    Marker Score: 61,219
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.65
    Marker Score: 12,618
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.63
    Marker Score: 6,294
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.62
    Marker Score: 34,675
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.62
    Marker Score: 13,952
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.57
    Marker Score: 1,212
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.57
    Marker Score: 1,443
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.57
    Marker Score: 14,757
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.56
    Marker Score: 3,435
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.55
    Marker Score: 23,136
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.53
    Marker Score: 57,948
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.52
    Marker Score: 638
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.49
    Marker Score: 15,386
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.48
    Marker Score: 6,116
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.46
    Marker Score: 2,258
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.44
    Marker Score: 456
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.4
    Marker Score: 27,906
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.4
    Marker Score: 1,607
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.39
    Marker Score: 4,791
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.33
    Marker Score: 3,133
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.29
    Marker Score: 678
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.25
    Marker Score: 4,435
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.23
    Marker Score: 1,328
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.23
    Marker Score: 335
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.18
    Marker Score: 2,276
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.16
    Marker Score: 26,024
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.16
    Marker Score: 1,110
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.15
    Marker Score: 1,652
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.15
    Marker Score: 1,266
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.14
    Marker Score: 4,786
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.13
    Marker Score: 5,213
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.11
    Marker Score: 357
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.09
    Marker Score: 17,521
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.07
    Marker Score: 1,294
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.07
    Marker Score: 1,791
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.06
    Marker Score: 1,423
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.05
    Marker Score: 302
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.04
    Marker Score: 1,473
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1.04
    Marker Score: 493
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.03
    Marker Score: 615
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.02
    Marker Score: 8,845
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.01
    Marker Score: 375
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.01
    Marker Score: 317
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,647
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.99
    Marker Score: 47,873
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,383
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.97
    Marker Score: 282
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.96
    Marker Score: 832
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.96
    Marker Score: 276
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.95
    Marker Score: 823
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.95
    Marker Score: 1,074
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.94
    Marker Score: 407
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,390
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.94
    Marker Score: 2,676
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 476
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 0.92
    Marker Score: 2,323
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.92
    Marker Score: 373
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.91
    Marker Score: 432
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.9
    Marker Score: 285
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2,692
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.9
    Marker Score: 653
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.89
    Marker Score: 1,079
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.89
    Marker Score: 3,287
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.89
    Marker Score: 940
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 0.89
    Marker Score: 1,424
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.88
    Marker Score: 1,104
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.88
    Marker Score: 1,428
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.88
    Marker Score: 453
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 0.87
    Marker Score: 271
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,293
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.87
    Marker Score: 302
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.86
    Marker Score: 417
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 308
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.84
    Marker Score: 219
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 0.84
    Marker Score: 5,486
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 0.84
    Marker Score: 2,356
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.84
    Marker Score: 28,281
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.84
    Marker Score: 628
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.83
    Marker Score: 4,748
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.83
    Marker Score: 842
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 0.83
    Marker Score: 2,224
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 0.82
    Marker Score: 8,167
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 0.81
    Marker Score: 1,005
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.81
    Marker Score: 406
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.81
    Marker Score: 295
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 0.81
    Marker Score: 1,520
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 0.81
    Marker Score: 172
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.81
    Marker Score: 302
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.8
    Marker Score: 328
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.8
    Marker Score: 176
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.8
    Marker Score: 483
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 0.8
    Marker Score: 226
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 0.8
    Marker Score: 2,517

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CABIN1 is a protein that binds to calcineurin, a phosphatase enzyme involved in the regulation of various cellular processes, including cell cycle progression and apoptosis. The protein is characterized by its ability to regulate the activity of calcineurin, thereby modulating the cellular response to stress. CABIN1 is also involved in the formation of SAHFs, which are nuclear structures that accumulate during cellular senescence. The protein's expression is tightly regulated and is often upregulated in response to DNA damage and telomere stress. **Pathways and Functions:** CABIN1 is involved in several cellular pathways, including: 1. **Aggresome formation**: CABIN1 plays a role in the formation of aggresomes, which are protein aggregates that accumulate in response to cellular stress. 2. **Cell surface receptor signaling pathway**: CABIN1 is involved in the regulation of cell surface receptor signaling pathways, including those involved in immune responses and cell growth. 3. **Cellular responses to stimuli**: CABIN1 modulates the cellular response to various stimuli, including DNA damage, telomere stress, and oxidative stress. 4. **Cellular responses to stress**: CABIN1 is involved in the regulation of cellular responses to stress, including apoptosis and senescence. 5. **Nucleosome assembly and regulation**: CABIN1 regulates the assembly and regulation of nucleosomes, which are the basic units of chromatin. **Functions:** CABIN1 has several functions, including: 1. **Regulation of calcineurin activity**: CABIN1 regulates the activity of calcineurin, which is involved in the regulation of various cellular processes. 2. **Modulation of SAHF formation**: CABIN1 is involved in the formation of SAHFs, which are nuclear structures that accumulate during cellular senescence. 3. **Regulation of apoptosis**: CABIN1 modulates the regulation of apoptosis, which is a process of programmed cell death. 4. **Regulation of cell growth and proliferation**: CABIN1 regulates the regulation of cell growth and proliferation in response to various stimuli. **Clinical Significance:** CABIN1 has several implications in human disease, including: 1. **Cancer**: Elevated expression of CABIN1 has been observed in various types of cancer, including breast, lung, and colon cancer. 2. **Aging and age-related diseases**: CABIN1 is involved in the regulation of cellular senescence and may play a role in the development of age-related diseases, such as Alzheimer's and Parkinson's disease. 3. **Neurological disorders**: CABIN1 is expressed in the brain and may play a role in the regulation of neuronal function and behavior. 4. **Immunological disorders**: CABIN1 is involved in the regulation of immune responses and may play a role in the development of immunological disorders, such as autoimmune diseases. In conclusion, CABIN1 is a protein that plays a significant role in the cellular response to stress and has several implications in human disease. Further research is needed to fully understand the function of CABIN1 and its role in various diseases.

Genular Protein ID: 3380417601

Symbol: CABIN_HUMAN

Name: Calcineurin-binding protein cabin-1

UniProtKB Accession Codes:

Q9Y6J0 G5E9F3 Q6PHY0 Q9Y460

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9655484

Title: Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes.

PubMed ID: 9655484

DOI: 10.1016/s1074-7613(00)80575-0

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 14718166

Title: Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis.

PubMed ID: 14718166

DOI: 10.1016/s0092-8674(03)01064-x

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23303793

Title: Phosphorylation and ubiquitination-dependent degradation of CABIN1 releases p53 for transactivation upon genotoxic stress.

PubMed ID: 23303793

DOI: 10.1093/nar/gks1319

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 12700764

Title: Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2.

PubMed ID: 12700764

DOI: 10.1038/nature01555

Sequence Information:

  • Length: 2220
  • Mass: 246352
  • Checksum: BA4AD1741056C233
  • Sequence:
    • MIRIAALNAS STIEDDHEGS FKSHKTQTKE AQEAEAFALY HKALDLQKHD RFEESAKAYH 
ELLEASLLRE AVSSGDEKEG LKHPGLILKY STYKNLAQLA AQREDLETAM EFYLEAVMLD 
STDVNLWYKI GHVALRLIRI PLARHAFEEG LRCNPDHWPC LDNLITVLYT LSDYTTCLYF 
ICKALEKDCR YSKGLVLKEK IFEEQPCLRK DSLRMFLKCD MSIHDVSVSA AETQAIVDEA 
LGLRKKRQAL IVREKEPDLK LVQPIPFFTW KCLGESLLAM YNHLTTCEPP RPSLGKRIDL 
SDYQDPSQPL ESSMVVTPVN VIQPSTVSTN PAVAVAEPVV SYTSVATTSF PLHSPGLLET 
GAPVGDISGG DKSKKGVKRK KISEESGETA KRRSARVRNT KCKKEEKVDF QELLMKFLPS 
RLRKLDPEEE DDSFNNYEVQ SEAKLESFPS IGPQRLSFDS ATFMESEKQD VHEFLLENLT 
NGGILELMMR YLKAMGHKFL VRWPPGLAEV VLSVYHSWRR HSTSLPNPLL RDCSNKHIKD 
MMLMSLSCME LQLDQWLLTK GRSSAVSPRN CPAGMVNGRF GPDFPGTHCL GDLLQLSFAS 
SQRDLFEDGW LEFVVRVYWL KARFLALQGD MEQALENYDI CTEMLQSSTA IQVEAGAERR 
DIVIRLPNLH NDSVVSLEEI DKNLKSLERC QSLEEIQRLY EAGDYKAVVH LLRPTLCTSG 
FDRAKHLEFM TSIPERPAQL LLLQDSLLRL KDYRQCFECS DVALNEAVQQ MVNSGEAAAK 
EEWVATVTQL LMGIEQALSA DSSGSILKVS SSTTGLVRLT NNLIQVIDCS MAVQEEAKEP 
HVSSVLPWII LHRIIWQEED TFHSLCHQQQ LQNPAEEGMS ETPMLPSSLM LLNTAHEYLG 
RRSWCCNSDG ALLRFYVRVL QKELAASTSE DTHPYKEELE TALEQCFYCL YSFPSKKSKA 
RYLEEHSAQQ VDLIWEDALF MFEYFKPKTL PEFDSYKTST VSADLANLLK RIATIVPRTE 
RPALSLDKVS AYIEGTSTEV PCLPEGADPS PPVVNELYYL LADYHFKNKE QSKAIKFYMH 
DICICPNRFD SWAGMALARA SRIQDKLNSN ELKSDGPIWK HATPVLNCFR RALEIDSSNL 
SLWIEYGTMS YALHSFASRQ LKQWRGELPP ELVQQMEGRR DSMLETAKHC FTSAARCEGD 
GDEEEWLIHY MLGKVAEKQQ QPPTVYLLHY RQAGHYLHEE AARYPKKIHY HNPPELAMEA 
LEVYFRLHAS ILKLLGKPDS GVGAEVLVNF MKEAAEGPFA RGEEKNTPKA SEKEKACLVD 
EDSHSSAGTL PGPGASLPSS SGPGLTSPPY TATPIDHDYV KCKKPHQQAT PDDRSQDSTA 
VALSDSSSTQ DFFNEPTSLL EGSRKSYTEK RLPILSSQAG ATGKDLQGAT EERGKNEESL 
ESTEGFRAAE QGVQKPAAET PASACIPGKP SASTPTLWDG KKRGDLPGEP VAFPQGLPAG 
AEEQRQFLTE QCIASFRLCL SRFPQHYKSL YRLAFLYTYS KTHRNLQWAR DVLLGSSIPW 
QQLQHMPAQG LFCERNKTNF FNGIWRIPVD EIDRPGSFAW HMNRSIVLLL KVLAQLRDHS 
TLLKVSSMLQ RTPDQGKKYL RDADRQVLAQ RAFILTVKVL EDTLSELAEG SERPGPKVCG 
LPGARMTTDV SHKASPEDGQ EGLPQPKKPP LADGSGPGPE PGGKVGLLNH RPVAMDAGDS 
ADQSGERKDK ESPRAGPTEP MDTSEATVCH SDLERTPPLL PGRPARDRGP ESRPTELSLE 
ELSISARQQP TPLTPAQPAP APAPATTTGT RAGGHPEEPL SRLSRKRKLL EDTESGKTLL 
LDAYRVWQQG QKGVAYDLGR VERIMSETYM LIKQVDEEAA LEQAVKFCQV HLGAAAQRQA 
SGDTPTTPKH PKDSRENFFP VTVVPTAPDP VPADSVQRPS DAHTKPRPAL AAATTIITCP 
PSASASTLDQ SKDPGPPRPH RPEATPSMAS LGPEGEELAR VAEGTSFPPQ EPRHSPQVKM 
APTSSPAEPH CWPAEAALGT GAEPTCSQEG KLRPEPRRDG EAQEAASETQ PLSSPPTAAS 
SKAPSSGSAQ PPEGHPGKPE PSRAKSRPLP NMPKLVIPSA ATKFPPEITV TPPTPTLLSP 
KGSISEETKQ KLKSAILSAQ SAANVRKESL CQPALEVLET SSQESSLESE TDEDDDYMDI

Genular Protein ID: 1224481767

Symbol: A0A087WWW8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WWW8

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 2170
  • Mass: 240766
  • Checksum: ADCCE2A52346245D
  • Sequence:
    • MIRIAALNAS STIEDDHEGS FKSHKTQTKE AQEAEAFALY HKALDLQKHD RFEESAKAYH 
ELLEASLLRE AVSSGDEKEG LKHPGLILKY STYKNLAQLA AQREDLETAM EFYLEAVMLD 
STDVNLWYKI GHVALRLIRI PLARHAFEEG LRCNPDHWPC LDNLITVLYT LSDYTTCLYF 
ICKALEKDCR YSKGLVLKEK IFEEQPCLRK DSLRMFLKCW KCLGESLLAM YNHLTTCEPP 
RPSLGKRIDL SDYQDPSQPL ESSMVVTPVN VIQPSTVSTN PAVAVAEPVV SYTSVATTSF 
PLHSPGLLET GAPVGDISGG DKSKKGVKRK KISEESGETA KRRSARVRNT KCKKEEKVDF 
QELLMKFLPS RLRKLDPEEE DDSFNNYEVQ SEAKLESFPS IGPQRLSFDS ATFMESEKQD 
VHEFLLENLT NGGILELMMR YLKAMGHKFL VRWPPGLAEV VLSVYHSWRR HSTSLPNPLL 
RDCSNKHIKD MMLMSLSCME LQLDQWLLTK GRSSAVSPRN CPAGMVNGRF GPDFPGTHCL 
GDLLQLSFAS SQRDLFEDGW LEFVVRVYWL KARFLALQGD MEQALENYDI CTEMLQSSTA 
IQVEAGAERR DIVIRLPNLH NDSVVSLEEI DKNLKSLERC QSLEEIQRLY EAGDYKAVVH 
LLRPTLCTSG FDRAKHLEFM TSIPERPAQL LLLQDSLLRL KDYRQCFECS DVALNEAVQQ 
MVNSGEAAAK EEWVATVTQL LMGIEQALSA DSSGSILKVS SSTTGLVRLT NNLIQVIDCS 
MAVQEEAKEP HVSSVLPWII LHRIIWQEED TFHSLCHQQQ LQNPAEEGMS ETPMLPSSLM 
LLNTAHEYLG RRSWCCNSDG ALLRFYVRVL QKELAASTSE DTHPYKEELE TALEQCFYCL 
YSFPSKKSKA RYLEEHSAQQ VDLIWEDALF MFEYFKPKTL PEFDSYKTST VSADLANLLK 
RIATIVPRTE RPALSLDKVS AYIEGTSTEV PCLPEGADPS PPVVNELYYL LADYHFKNKE 
QSKAIKFYMH DICICPNRFD SWAGMALARA SRIQDKLNSN ELKSDGPIWK HATPVLNCFR 
RALEIDSSNL SLWIEYGTMS YALHSFASRQ LKQWRGELPP ELVQQMEGRR DSMLETAKHC 
FTSAARCEGD GDEEEWLIHY MLGKVAEKQQ QPPTVYLLHY RQAGHYLHEE AARYPKKIHY 
HNPPELAMEA LEVYFRLHAS ILKLLGKPDS GVGAEVLVNF MKEAAEGPFA RGEEKNTPKA 
SEKEKACLVD EDSHSSAGTL PGPGASLPSS SGPGLTSPPY TATPIDHDYV KCKKPHQQAT 
PDDRSQDSTA VALSDSSSTQ DFFNEPTSLL EGSRKSYTEK RLPILSSQAG ATGKDLQGAT 
EERGKNEESL ESTEGFRAAE QGVQKPAAET PASACIPGKP SASTPTLWDG KKRGDLPGEP 
VAFPQGLPAG AEEQRQFLTE QCIASFRLCL SRFPQHYKSL YRLAFLYTYS KTHRNLQWAR 
DVLLGSSIPW QQLQHMPAQG LFCERNKTNF FNGIWRIPVD EIDRPGSFAW HMNRSIVLLL 
KVLAQLRDHS TLLKVSSMLQ RTPDQGKKYL RDADRQVLAQ RAFILTVKVL EDTLSELAEG 
SERPGPKVCG LPGARMTTDV SHKASPEDGQ EGLPQPKKPP LADGSGPGPE PGGKVGLLNH 
RPVAMDAGDS ADQSGERKDK ESPRAGPTEP MDTSEATVCH SDLERTPPLL PGRPARDRGP 
ESRPTELSLE ELSISARQQP TPLTPAQPAP APAPATTTGT RAGGHPEEPL SRLSRKRKLL 
EDTESGKTLL LDAYRVWQQG QKGVAYDLGR VERIMSETYM LIKQVDEEAA LEQAVKFCQV 
HLGAAAQRQA SGDTPTTPKH PKDSRENFFP VTVVPTAPDP VPADSVQRPS DAHTKPRPAL 
AAATTIITCP PSASASTLDQ SKDPGPPRPH RPEATPSMAS LGPEGEELAR VAEGTSFPPQ 
EPRHSPQVKM APTSSPAEPH CWPAEAALGT GAEPTCSQEG KLRPEPRRDG EAQEAASETQ 
PLSSPPTAAS SKAPSSGSAQ PPEGHPGKPE PSRAKSRPLP NMPKLVIPSA ATKFPPEITV 
TPPTPTLLSP KGSISEETKQ KLKSAILSAQ SAANVRKESL CQPALEVLET SSQESSLESE 
TDEDDDYMDI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.