CLCF1 | ENSG00000175505 | NCBI 23529

Details for: CLCF1

Gene ID: 23529

Symbol: CLCF1

Ensembl ID: ENSG00000175505

Description: cardiotrophin like cytokine factor 1

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Il-6-type cytokine receptor ligand interactions
(R-HSA-6788467)
Immune system
(R-HSA-168256)
Interleukin-6 family signaling
(R-HSA-6783589)
Signaling by interleukins
(R-HSA-449147)
B cell differentiation
(GO:0030183)
Cell surface receptor signaling pathway
(GO:0007166)
Ciliary neurotrophic factor receptor binding
(GO:0005127)
Cntfr-clcf1 complex
(GO:0097059)
Crlf-clcf1 complex
(GO:0097058)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine activity
(GO:0005125)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Growth factor activity
(GO:0008083)
Negative regulation of neuron apoptotic process
(GO:0043524)
Positive regulation of astrocyte differentiation
(GO:0048711)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of immunoglobulin production
(GO:0002639)
Positive regulation of isotype switching to ige isotypes
(GO:0048295)
Positive regulation of tyrosine phosphorylation of stat protein
(GO:0042531)
Protein binding
(GO:0005515)
Receptor signaling pathway via jak-stat
(GO:0007259)
Signaling receptor binding
(GO:0005102)

Other Information

Proteins

Cardiotrophin-like cytokine factor 1

Genular Protein ID: 2250667807

Symbol: CLCF1_HUMAN

Name: Cardiotrophin-like cytokine factor 1

UniProtKB Accession Codes:

Q9UBD9 B4DNT4 Q6NZA4

Database IDs:

Citations:

PubMed ID: 10500198

Title: Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family.

PubMed ID: 10500198

DOI: 10.1073/pnas.96.20.11458

PubMed ID: 10448081

Title: Computational EST database analysis identifies a novel member of the neuropoietic cytokine family.

PubMed ID: 10448081

DOI: 10.1006/bbrc.1999.1181

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 26858303

Title: Cytokine-like factor 1, an essential facilitator of cardiotrophin-like cytokine:ciliary neurotrophic factor receptor alpha signaling and sorLA-mediated turnover.

PubMed ID: 26858303

DOI: 10.1128/mcb.00917-15

PubMed ID: 16782820

Title: Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patient.

PubMed ID: 16782820

DOI: 10.1073/pnas.0509598103

Sequence Information:

Length: 225
Mass: 25176
Checksum: E2DD4B6280833B55
Sequence:

MDLRAGDSWG MLACLCTVLW HLPAVPALNR TGDPGPGPSI QKTYDLTRYL EHQLRSLAGT 
YLNYLGPPFN EPDFNPPRLG AETLPRATVD LEVWRSLNDK LRLTQNYEAY SHLLCYLRGL 
NRQAATAELR RSLAHFCTSL QGLLGSIAGV MAALGYPLPQ PLPGTEPTWT PGPAHSDFLQ 
KMDDFWLLKE LQTWLWRSAK DFNRLKKKMQ PPAAAVTLHL GAHGF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CLCF1

Associated with

Other Information

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family. PubMed ID: 10500198

Computational EST database analysis identifies a novel member of the neuropoietic cytokine family. PubMed ID: 10448081

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Human chromosome 11 DNA sequence and analysis including novel gene identification. PubMed ID: 16554811

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cytokine-like factor 1, an essential facilitator of cardiotrophin-like cytokine:ciliary neurotrophic factor receptor alpha signaling and sorLA-mediated turnover. PubMed ID: 26858303

Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patient. PubMed ID: 16782820