Details for: NNT
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 3.11
Marker Score: 69,529 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 2.25
Marker Score: 1,187 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.13
Marker Score: 4,672 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 2.01
Marker Score: 5,396 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.98
Marker Score: 2,096 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.97
Marker Score: 72,539 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.91
Marker Score: 7,911 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 1.89
Marker Score: 3,138 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.86
Marker Score: 6,601 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.84
Marker Score: 1,069 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.83
Marker Score: 112,497 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.79
Marker Score: 68,011 - Cell Name: neuron (CL0000540)
Fold Change: 1.75
Marker Score: 7,109 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.74
Marker Score: 6,716 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.71
Marker Score: 14,713 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.71
Marker Score: 16,264 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.71
Marker Score: 34,009 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.71
Marker Score: 16,044 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.67
Marker Score: 17,195 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.66
Marker Score: 24,810 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.63
Marker Score: 34,875 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.62
Marker Score: 12,399 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.61
Marker Score: 4,027 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.59
Marker Score: 7,378 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.54
Marker Score: 2,375 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.54
Marker Score: 6,629 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.52
Marker Score: 9,742 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.47
Marker Score: 7,896 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.39
Marker Score: 1,111 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.39
Marker Score: 405 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 1.38
Marker Score: 503 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.38
Marker Score: 46,468 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.37
Marker Score: 576 - Cell Name: fat cell (CL0000136)
Fold Change: 1.32
Marker Score: 736 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 1.29
Marker Score: 3,262 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.25
Marker Score: 19,552 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.23
Marker Score: 5,138 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.21
Marker Score: 935 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.2
Marker Score: 2,311 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.13
Marker Score: 3,212 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.12
Marker Score: 356 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.11
Marker Score: 3,023 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.11
Marker Score: 1,572 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.11
Marker Score: 302 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.1
Marker Score: 1,262 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.09
Marker Score: 529 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.07
Marker Score: 1,024 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.07
Marker Score: 924 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.05
Marker Score: 712 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1.03
Marker Score: 1,047 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.02
Marker Score: 393 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.02
Marker Score: 380 - Cell Name: osteoclast (CL0000092)
Fold Change: 1.02
Marker Score: 506 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.01
Marker Score: 1,093 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.01
Marker Score: 256 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,670 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47,895 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.99
Marker Score: 998 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.99
Marker Score: 2,321 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,386 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 0.98
Marker Score: 568 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 0.97
Marker Score: 1,209 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.96
Marker Score: 656 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.95
Marker Score: 1,179 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 0.95
Marker Score: 312 - Cell Name: renal intercalated cell (CL0005010)
Fold Change: 0.95
Marker Score: 504 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,394 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.94
Marker Score: 465 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.93
Marker Score: 992 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.92
Marker Score: 476 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.92
Marker Score: 516 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 433 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.92
Marker Score: 9,280 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.91
Marker Score: 289 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,696 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.9
Marker Score: 1,015 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.89
Marker Score: 5,087 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.89
Marker Score: 562 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.88
Marker Score: 2,105 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,293 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.87
Marker Score: 275 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.86
Marker Score: 293 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.85
Marker Score: 510 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 307 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.84
Marker Score: 553 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.84
Marker Score: 1,411 - Cell Name: podocyte (CL0000653)
Fold Change: 0.84
Marker Score: 310 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.84
Marker Score: 768 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.83
Marker Score: 2,957 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.83
Marker Score: 4,356 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 0.83
Marker Score: 218 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.82
Marker Score: 334 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.82
Marker Score: 13,203 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.82
Marker Score: 4,938 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.82
Marker Score: 2,011 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 0.82
Marker Score: 309 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.81
Marker Score: 504 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.8
Marker Score: 14,273 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.8
Marker Score: 322 - Cell Name: stellate neuron (CL0000122)
Fold Change: 0.79
Marker Score: 4,251
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3823915336
Symbol: NNTM_HUMAN
Name: NAD(P) transhydrogenase, mitochondrial
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9524818
Title: Cloning and deduced amino acid sequence of human nicotinamide nucleotide transhydrogenase.
PubMed ID: 9524818
PubMed ID: 8616157
Title: The cDNA sequence of proton-pumping nicotinamide nucleotide transhydrogenase from man and mouse.
PubMed ID: 8616157
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22634753
Title: Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency.
PubMed ID: 22634753
DOI: 10.1038/ng.2299
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 10673423
Title: The high-resolution structure of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase from human heart mitochondria.
PubMed ID: 10673423
PubMed ID: 12791694
Title: Interactions between transhydrogenase and thio-nicotinamide Analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation.
PubMed ID: 12791694
PubMed ID: 15323555
Title: Active-site conformational changes associated with hydride transfer in proton-translocating transhydrogenase.
PubMed ID: 15323555
DOI: 10.1021/bi0497594
Sequence Information:
- Length: 1086
- Mass: 113896
- Checksum: 8A437658CA0EB41B
- Sequence:
MANLLKTVVT GCSCPLLSNL GSCKGLRVKK DFLRTFYTHQ ELWCKAPVKP GIPYKQLTVG VPKEIFQNEK RVALSPAGVQ NLVKQGFNVV VESGAGEASK FSDDHYRVAG AQIQGAKEVL ASDLVVKVRA PMVNPTLGVH EADLLKTSGT LISFIYPAQN PELLNKLSQR KTTVLAMDQV PRVTIAQGYD ALSSMANIAG YKAVVLAANH FGRFFTGQIT AAGKVPPAKI LIVGGGVAGL ASAGAAKSMG AIVRGFDTRA AALEQFKSLG AEPLEVDLKE SGEGQGGYAK EMSKEFIEAE MKLFAQQCKE VDILISTALI PGKKAPVLFN KEMIESMKEG SVVVDLAAEA GGNFETTKPG ELYIHKGITH IGYTDLPSRM ATQASTLYSN NITKLLKAIS PDKDNFYFDV KDDFDFGTMG HVIRGTVVMK DGKVIFPAPT PKNIPQGAPV KQKTVAELEA EKAATITPFR KTMSTASAYT AGLTGILGLG IAAPNLAFSQ MVTTFGLAGI VGYHTVWGVT PALHSPLMSV TNAISGLTAV GGLALMGGHL YPSTTSQGLA ALAAFISSVN IAGGFLVTQR MLDMFKRPTD PPEYNYLYLL PAGTFVGGYL AALYSGYNIE QIMYLGSGLC CVGALAGLST QGTARLGNAL GMIGVAGGLA ATLGVLKPGP ELLAQMSGAM ALGGTIGLTI AKRIQISDLP QLVAAFHSLV GLAAVLTCIA EYIIEYPHFA TDAAANLTKI VAYLGTYIGG VTFSGSLIAY GKLQGLLKSA PLLLPGRHLL NAGLLAASVG GIIPFMVDPS FTTGITCLGS VSALSAVMGV TLTAAIGGAD MPVVITVLNS YSGWALCAEG FLLNNNLLTI VGALIGSSGA ILSYIMCVAM NRSLANVILG GYGTTSTAGG KPMEISGTHT EINLDNAIDM IREANSIIIT PGYGLCAAKA QYPIADLVKM LTEQGKKVRF GIHPVAGRMP GQLNVLLAEA GVPYDIVLEM DEINHDFPDT DLVLVIGAND TVNSAAQEDP NSIIAGMPVL EVWKSKQVIV MKRSLGVGYA AVDNPIFYKP NTAMLLGDAK KTCDALQAKV RESYQK
Genular Protein ID: 923867736
Symbol: E9PCX7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 955
- Mass: 99729
- Checksum: AA59856439D9CE1C
- Sequence:
MVNPTLGVHE ADLLKTSGTL ISFIYPAQNP ELLNKLSQRK TTVLAMDQVP RVTIAQGYDA LSSMANIAGY KAVVLAANHF GRFFTGQITA AGKVPPAKIL IVGGGVAGLA SAGAAKSMGA IVRGFDTRAA ALEQFKSLGA EPLEVDLKES GEGQGGYAKE MSKEFIEAEM KLFAQQCKEV DILISTALIP GKKAPVLFNK EMIESMKEGS VVVDLAAEAG GNFETTKPGE LYIHKGITHI GYTDLPSRMA TQASTLYSNN ITKLLKAISP DKDNFYFDVK DDFDFGTMGH VIRGTVVMKD GKVIFPAPTP KNIPQGAPVK QKTVAELEAE KAATITPFRK TMSTASAYTA GLTGILGLGI AAPNLAFSQM VTTFGLAGIV GYHTVWGVTP ALHSPLMSVT NAISGLTAVG GLALMGGHLY PSTTSQGLAA LAAFISSVNI AGGFLVTQRM LDMFKRPTDP PEYNYLYLLP AGTFVGGYLA ALYSGYNIEQ IMYLGSGLCC VGALAGLSTQ GTARLGNALG MIGVAGGLAA TLGVLKPGPE LLAQMSGAMA LGGTIGLTIA KRIQISDLPQ LVAAFHSLVG LAAVLTCIAE YIIEYPHFAT DAAANLTKIV AYLGTYIGGV TFSGSLIAYG KLQGLLKSAP LLLPGRHLLN AGLLAASVGG IIPFMVDPSF TTGITCLGSV SALSAVMGVT LTAAIGGADM PVVITVLNSY SGWALCAEGF LLNNNLLTIV GALIGSSGAI LSYIMCVAMN RSLANVILGG YGTTSTAGGK PMEISGTHTE INLDNAIDMI REANSIIITP GYGLCAAKAQ YPIADLVKML TEQGKKVRFG IHPVAGRMPG QLNVLLAEAG VPYDIVLEMD EINHDFPDTD LVLVIGANDT VNSAAQEDPN SIIAGMPVLE VWKSKQVIVM KRSLGVGYAA VDNPIFYKPN TAMLLGDAKK TCDALQAKVR ESYQK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.