Details for: NNT

Gene ID: 23530

Symbol: NNT

Ensembl ID: ENSG00000112992

Description: nicotinamide nucleotide transhydrogenase

Associated with

Other Information

Genular Protein ID: 3823915336

Symbol: NNTM_HUMAN

Name: NAD(P) transhydrogenase, mitochondrial

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9524818

Title: Cloning and deduced amino acid sequence of human nicotinamide nucleotide transhydrogenase.

PubMed ID: 9524818

DOI: 10.3109/10425179709034058

PubMed ID: 8616157

Title: The cDNA sequence of proton-pumping nicotinamide nucleotide transhydrogenase from man and mouse.

PubMed ID: 8616157

DOI: 10.1016/0005-2728(95)00159-x

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22634753

Title: Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency.

PubMed ID: 22634753

DOI: 10.1038/ng.2299

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 10673423

Title: The high-resolution structure of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase from human heart mitochondria.

PubMed ID: 10673423

DOI: 10.1016/s0969-2126(00)00075-7

PubMed ID: 12791694

Title: Interactions between transhydrogenase and thio-nicotinamide Analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation.

PubMed ID: 12791694

DOI: 10.1074/jbc.m303061200

PubMed ID: 15323555

Title: Active-site conformational changes associated with hydride transfer in proton-translocating transhydrogenase.

PubMed ID: 15323555

DOI: 10.1021/bi0497594

Sequence Information:

  • Length: 1086
  • Mass: 113896
  • Checksum: 8A437658CA0EB41B
  • Sequence:
  • MANLLKTVVT GCSCPLLSNL GSCKGLRVKK DFLRTFYTHQ ELWCKAPVKP GIPYKQLTVG 
    VPKEIFQNEK RVALSPAGVQ NLVKQGFNVV VESGAGEASK FSDDHYRVAG AQIQGAKEVL 
    ASDLVVKVRA PMVNPTLGVH EADLLKTSGT LISFIYPAQN PELLNKLSQR KTTVLAMDQV 
    PRVTIAQGYD ALSSMANIAG YKAVVLAANH FGRFFTGQIT AAGKVPPAKI LIVGGGVAGL 
    ASAGAAKSMG AIVRGFDTRA AALEQFKSLG AEPLEVDLKE SGEGQGGYAK EMSKEFIEAE 
    MKLFAQQCKE VDILISTALI PGKKAPVLFN KEMIESMKEG SVVVDLAAEA GGNFETTKPG 
    ELYIHKGITH IGYTDLPSRM ATQASTLYSN NITKLLKAIS PDKDNFYFDV KDDFDFGTMG 
    HVIRGTVVMK DGKVIFPAPT PKNIPQGAPV KQKTVAELEA EKAATITPFR KTMSTASAYT 
    AGLTGILGLG IAAPNLAFSQ MVTTFGLAGI VGYHTVWGVT PALHSPLMSV TNAISGLTAV 
    GGLALMGGHL YPSTTSQGLA ALAAFISSVN IAGGFLVTQR MLDMFKRPTD PPEYNYLYLL 
    PAGTFVGGYL AALYSGYNIE QIMYLGSGLC CVGALAGLST QGTARLGNAL GMIGVAGGLA 
    ATLGVLKPGP ELLAQMSGAM ALGGTIGLTI AKRIQISDLP QLVAAFHSLV GLAAVLTCIA 
    EYIIEYPHFA TDAAANLTKI VAYLGTYIGG VTFSGSLIAY GKLQGLLKSA PLLLPGRHLL 
    NAGLLAASVG GIIPFMVDPS FTTGITCLGS VSALSAVMGV TLTAAIGGAD MPVVITVLNS 
    YSGWALCAEG FLLNNNLLTI VGALIGSSGA ILSYIMCVAM NRSLANVILG GYGTTSTAGG 
    KPMEISGTHT EINLDNAIDM IREANSIIIT PGYGLCAAKA QYPIADLVKM LTEQGKKVRF 
    GIHPVAGRMP GQLNVLLAEA GVPYDIVLEM DEINHDFPDT DLVLVIGAND TVNSAAQEDP 
    NSIIAGMPVL EVWKSKQVIV MKRSLGVGYA AVDNPIFYKP NTAMLLGDAK KTCDALQAKV 
    RESYQK

Genular Protein ID: 923867736

Symbol: E9PCX7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 955
  • Mass: 99729
  • Checksum: AA59856439D9CE1C
  • Sequence:
  • MVNPTLGVHE ADLLKTSGTL ISFIYPAQNP ELLNKLSQRK TTVLAMDQVP RVTIAQGYDA 
    LSSMANIAGY KAVVLAANHF GRFFTGQITA AGKVPPAKIL IVGGGVAGLA SAGAAKSMGA 
    IVRGFDTRAA ALEQFKSLGA EPLEVDLKES GEGQGGYAKE MSKEFIEAEM KLFAQQCKEV 
    DILISTALIP GKKAPVLFNK EMIESMKEGS VVVDLAAEAG GNFETTKPGE LYIHKGITHI 
    GYTDLPSRMA TQASTLYSNN ITKLLKAISP DKDNFYFDVK DDFDFGTMGH VIRGTVVMKD 
    GKVIFPAPTP KNIPQGAPVK QKTVAELEAE KAATITPFRK TMSTASAYTA GLTGILGLGI 
    AAPNLAFSQM VTTFGLAGIV GYHTVWGVTP ALHSPLMSVT NAISGLTAVG GLALMGGHLY 
    PSTTSQGLAA LAAFISSVNI AGGFLVTQRM LDMFKRPTDP PEYNYLYLLP AGTFVGGYLA 
    ALYSGYNIEQ IMYLGSGLCC VGALAGLSTQ GTARLGNALG MIGVAGGLAA TLGVLKPGPE 
    LLAQMSGAMA LGGTIGLTIA KRIQISDLPQ LVAAFHSLVG LAAVLTCIAE YIIEYPHFAT 
    DAAANLTKIV AYLGTYIGGV TFSGSLIAYG KLQGLLKSAP LLLPGRHLLN AGLLAASVGG 
    IIPFMVDPSF TTGITCLGSV SALSAVMGVT LTAAIGGADM PVVITVLNSY SGWALCAEGF 
    LLNNNLLTIV GALIGSSGAI LSYIMCVAMN RSLANVILGG YGTTSTAGGK PMEISGTHTE 
    INLDNAIDMI REANSIIITP GYGLCAAKAQ YPIADLVKML TEQGKKVRFG IHPVAGRMPG 
    QLNVLLAEAG VPYDIVLEMD EINHDFPDTD LVLVIGANDT VNSAAQEDPN SIIAGMPVLE 
    VWKSKQVIVM KRSLGVGYAA VDNPIFYKPN TAMLLGDAKK TCDALQAKVR ESYQK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.