PIK3R5 | ENSG00000141506 | NCBI 23533

Details for: PIK3R5

Gene ID: 23533

Symbol: PIK3R5

Ensembl ID: ENSG00000141506

Description: phosphoinositide-3-kinase regulatory subunit 5

Associated with

Erythropoietin activates phosphoinositide-3-kinase (pi3k)
(R-HSA-9027276)
G-protein beta:gamma signalling
(R-HSA-397795)
G beta:gamma signalling through pi3kgamma
(R-HSA-392451)
Gpcr downstream signalling
(R-HSA-388396)
Gpvi-mediated activation cascade
(R-HSA-114604)
Hemostasis
(R-HSA-109582)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Phospholipid metabolism
(R-HSA-1483257)
Pi metabolism
(R-HSA-1483255)
Platelet activation, signaling and aggregation
(R-HSA-76002)
Signaling by erythropoietin
(R-HSA-9006335)
Signaling by gpcr
(R-HSA-372790)
Signal transduction
(R-HSA-162582)
Synthesis of pips at the plasma membrane
(R-HSA-1660499)
1-phosphatidylinositol-3-kinase regulator activity
(GO:0046935)
Centriolar satellite
(GO:0034451)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
G-protein beta/gamma-subunit complex binding
(GO:0031683)
G protein-coupled receptor signaling pathway
(GO:0007186)
Immune response
(GO:0006955)
Membrane
(GO:0016020)
Nucleus
(GO:0005634)
Phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0043491)
Phosphatidylinositol 3-kinase complex
(GO:0005942)
Phosphatidylinositol 3-kinase complex, class ia
(GO:0005943)
Phosphatidylinositol 3-kinase complex, class ib
(GO:0005944)
Phosphatidylinositol metabolic process
(GO:0046488)
Plasma membrane
(GO:0005886)
Positive regulation of map kinase activity
(GO:0043406)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)

Other Information

Proteins

Phosphoinositide 3-kinase regulatory subunit 5

Genular Protein ID: 4066238587

Symbol: PI3R5_HUMAN

Name: Phosphoinositide 3-kinase regulatory subunit 5

UniProtKB Accession Codes:

Q8WYR1 B0LPH4 D3DTS3 Q5G936 Q5G938 Q5G939 Q8IZ23 Q9Y2Y2

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15797027

Title: p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma.

PubMed ID: 15797027

DOI: 10.1016/j.cub.2005.02.020

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 22065524

Title: A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia.

PubMed ID: 22065524

DOI: 10.1002/humu.21650

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 880
Mass: 97348
Checksum: 70E356773B148A8A
Sequence:

MQPGATTCTE DRIQHALERC LHGLSLSRRS TSWSAGLCLN CWSLQELVSR DPGHFLILLE 
QILQKTREVQ EKGTYDLLTP LALLFYSTVL CTPHFPPDSD LLLKAASTYH RFLTWPVPYC 
SICQELLTFI DAELKAPGIS YQRLVRAEQG LPIRSHRSST VTVLLLNPVE VQAEFLAVAN 
KLSTPGHSPH SAYTTLLLHA FQATFGAHCD VPGLHCRLQA KTLAELEDIF TETAEAQELA 
SGIGDAAEAR RWLRTKLQAV GEKAGFPGVL DTAKPGKLHT IPIPVARCYT YSWSQDSFDI 
LQEILLKEQE LLQPGILGDD EEEEEEEEEV EEDLETDGHC AERDSLLSTS SLASHDSTLS 
LASSQASGPA LSRHLLTSFV SGLSDGMDSG YVEDSEESSS EWPWRRGSQE RRGHRRPGQK 
FIRIYKLFKS TSQLVLRRDS RSLEGSSDTA LPLRRAGSLC SPLDEPVSPP SRAQRSRSLP 
QPKLGTQLPS WLLAPASRPQ RRRPFLSGDE DPKASTLRVV VFGSDRISGK VARAYSNLRR 
LENNRPLLTR FFKLQFFYVP VKRSHGTSPG ACPPPRSQTP SPPTDSPRHA SPGELGTTPW 
EESTNDISHY LGMLDPWYER NVLGLMHLPP EVLCQQSLKA EAQALEGSPT QLPILADMLL 
YYCRFAARPV LLQVYQTELT FITGEKTTEI FIHSLELGHS AATRAIKASG PGSKRLGIDG 
DREAVPLTLQ IIYSKGAISG RSRWSNLEKV CTSVNLNKAC RKQEELDSSM EALTLNLTEV 
VKRQNSKSKK GFNQISTSQI KVDKVQIIGS NSCPFAVCLD QDERKILQSV VRCEVSPCYK 
PEKSDLSSPP QTPPDLPAQA APDLCSLLCL PIMTFSGALP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: PIK3R5

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma. PubMed ID: 15797027

Large-scale proteomics analysis of the human kinome. PubMed ID: 19369195