Details for: PIK3R5
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 2.27
Marker Score: 1,129 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 2.24
Marker Score: 811 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.58
Marker Score: 1,146 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,678 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.38
Marker Score: 446 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.28
Marker Score: 769 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.14
Marker Score: 4,778 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.14
Marker Score: 472 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 1.1
Marker Score: 3,479 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.1
Marker Score: 61,604 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,780 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,004 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 0.99
Marker Score: 1,928 - Cell Name: lung macrophage (CL1001603)
Fold Change: 0.99
Marker Score: 1,132 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,405 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.97
Marker Score: 659 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.96
Marker Score: 494 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.95
Marker Score: 448 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,410 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.92
Marker Score: 5,252 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,736 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.91
Marker Score: 1,660 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.91
Marker Score: 364 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 0.9
Marker Score: 903 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.88
Marker Score: 318 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.88
Marker Score: 404 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,272 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 0.87
Marker Score: 2,099 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.85
Marker Score: 13,314 - Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 0.85
Marker Score: 1,247 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 0.8
Marker Score: 706 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.8
Marker Score: 610 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 0.8
Marker Score: 1,945 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 0.8
Marker Score: 4,836 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.77
Marker Score: 334 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 0.77
Marker Score: 1,068 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.77
Marker Score: 1,243 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 0.76
Marker Score: 231 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.76
Marker Score: 39,970 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.74
Marker Score: 385 - Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 0.73
Marker Score: 263 - Cell Name: brush cell (CL0002204)
Fold Change: 0.73
Marker Score: 666 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 0.73
Marker Score: 2,035 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 0.71
Marker Score: 18,305 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.7
Marker Score: 448 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 174 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.67
Marker Score: 1,070 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.67
Marker Score: 337 - Cell Name: Unknown (CL0000548)
Fold Change: 0.67
Marker Score: 485 - Cell Name: macrophage (CL0000235)
Fold Change: 0.66
Marker Score: 737 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 0.66
Marker Score: 2,817 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.65
Marker Score: 869 - Cell Name: blood cell (CL0000081)
Fold Change: 0.64
Marker Score: 7,435 - Cell Name: amacrine cell (CL0000561)
Fold Change: 0.63
Marker Score: 2,019 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 0.63
Marker Score: 641 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.63
Marker Score: 194 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 0.62
Marker Score: 455 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: 0.61
Marker Score: 376 - Cell Name: mature T cell (CL0002419)
Fold Change: 0.59
Marker Score: 5,802 - Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 0.58
Marker Score: 242 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 443 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.55
Marker Score: 391 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 0.55
Marker Score: 448 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 0.54
Marker Score: 510 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 0.54
Marker Score: 1,397 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: 0.54
Marker Score: 505 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 0.53
Marker Score: 267 - Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 0.53
Marker Score: 1,549 - Cell Name: classical monocyte (CL0000860)
Fold Change: 0.52
Marker Score: 2,176 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.52
Marker Score: 296 - Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 0.52
Marker Score: 503 - Cell Name: plasmacytoid dendritic cell, human (CL0001058)
Fold Change: 0.51
Marker Score: 133 - Cell Name: intermediate monocyte (CL0002393)
Fold Change: 0.5
Marker Score: 173 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 0.5
Marker Score: 1,235 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 0.49
Marker Score: 969 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 0.48
Marker Score: 332 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.48
Marker Score: 151 - Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
Fold Change: 0.47
Marker Score: 418 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 0.46
Marker Score: 816 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 0.45
Marker Score: 378 - Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
Fold Change: 0.45
Marker Score: 769 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 0.45
Marker Score: 396 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.44
Marker Score: 186 - Cell Name: ILC1, human (CL0001077)
Fold Change: 0.44
Marker Score: 112 - Cell Name: dendritic cell (CL0000451)
Fold Change: 0.44
Marker Score: 300 - Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
Fold Change: 0.44
Marker Score: 472 - Cell Name: monocyte (CL0000576)
Fold Change: 0.43
Marker Score: 564 - Cell Name: neutrophil (CL0000775)
Fold Change: 0.43
Marker Score: 259 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 0.41
Marker Score: 449 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.41
Marker Score: 225 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.41
Marker Score: 425 - Cell Name: natural killer cell (CL0000623)
Fold Change: 0.4
Marker Score: 525 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.4
Marker Score: 822 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.4
Marker Score: 107 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.4
Marker Score: 761 - Cell Name: memory T cell (CL0000813)
Fold Change: 0.4
Marker Score: 172 - Cell Name: IgM plasma cell (CL0000986)
Fold Change: 0.39
Marker Score: 137 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.38
Marker Score: 229 - Cell Name: IgA plasma cell (CL0000987)
Fold Change: 0.36
Marker Score: 310 - Cell Name: mature NK T cell (CL0000814)
Fold Change: 0.36
Marker Score: 167
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4066238587
Symbol: PI3R5_HUMAN
Name: Phosphoinositide 3-kinase regulatory subunit 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15797027
Title: p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma.
PubMed ID: 15797027
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 22065524
Title: A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia.
PubMed ID: 22065524
DOI: 10.1002/humu.21650
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 880
- Mass: 97348
- Checksum: 70E356773B148A8A
- Sequence:
MQPGATTCTE DRIQHALERC LHGLSLSRRS TSWSAGLCLN CWSLQELVSR DPGHFLILLE QILQKTREVQ EKGTYDLLTP LALLFYSTVL CTPHFPPDSD LLLKAASTYH RFLTWPVPYC SICQELLTFI DAELKAPGIS YQRLVRAEQG LPIRSHRSST VTVLLLNPVE VQAEFLAVAN KLSTPGHSPH SAYTTLLLHA FQATFGAHCD VPGLHCRLQA KTLAELEDIF TETAEAQELA SGIGDAAEAR RWLRTKLQAV GEKAGFPGVL DTAKPGKLHT IPIPVARCYT YSWSQDSFDI LQEILLKEQE LLQPGILGDD EEEEEEEEEV EEDLETDGHC AERDSLLSTS SLASHDSTLS LASSQASGPA LSRHLLTSFV SGLSDGMDSG YVEDSEESSS EWPWRRGSQE RRGHRRPGQK FIRIYKLFKS TSQLVLRRDS RSLEGSSDTA LPLRRAGSLC SPLDEPVSPP SRAQRSRSLP QPKLGTQLPS WLLAPASRPQ RRRPFLSGDE DPKASTLRVV VFGSDRISGK VARAYSNLRR LENNRPLLTR FFKLQFFYVP VKRSHGTSPG ACPPPRSQTP SPPTDSPRHA SPGELGTTPW EESTNDISHY LGMLDPWYER NVLGLMHLPP EVLCQQSLKA EAQALEGSPT QLPILADMLL YYCRFAARPV LLQVYQTELT FITGEKTTEI FIHSLELGHS AATRAIKASG PGSKRLGIDG DREAVPLTLQ IIYSKGAISG RSRWSNLEKV CTSVNLNKAC RKQEELDSSM EALTLNLTEV VKRQNSKSKK GFNQISTSQI KVDKVQIIGS NSCPFAVCLD QDERKILQSV VRCEVSPCYK PEKSDLSSPP QTPPDLPAQA APDLCSLLCL PIMTFSGALP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.