Details for: TNPO3

Gene ID: 23534

Symbol: TNPO3

Ensembl ID: ENSG00000064419

Description: transportin 3

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.79
    Marker Score: 1,973
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.63
    Marker Score: 100,230
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.6
    Marker Score: 31,904
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.6
    Marker Score: 15,217
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.57
    Marker Score: 58,028
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.55
    Marker Score: 14,595
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.54
    Marker Score: 15,874
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.53
    Marker Score: 13,135
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.51
    Marker Score: 57,410
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.51
    Marker Score: 22,554
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.5
    Marker Score: 32,107
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.49
    Marker Score: 1,291
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.49
    Marker Score: 26,424
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.46
    Marker Score: 5,656
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.45
    Marker Score: 6,004
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.38
    Marker Score: 2,129
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.36
    Marker Score: 10,416
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.35
    Marker Score: 5,485
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.32
    Marker Score: 552
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.31
    Marker Score: 2,877
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.29
    Marker Score: 1,466
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.25
    Marker Score: 1,350
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.23
    Marker Score: 1,420
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.23
    Marker Score: 1,657
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.22
    Marker Score: 41,093
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.22
    Marker Score: 937
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.21
    Marker Score: 5,072
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.21
    Marker Score: 354
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.16
    Marker Score: 2,230
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.15
    Marker Score: 426
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.09
    Marker Score: 5,065
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.09
    Marker Score: 651
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.06
    Marker Score: 1,276
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.04
    Marker Score: 549
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.04
    Marker Score: 833
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.04
    Marker Score: 283
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.03
    Marker Score: 6,644
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.02
    Marker Score: 593
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.02
    Marker Score: 689
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.01
    Marker Score: 499
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.01
    Marker Score: 490
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1
    Marker Score: 697
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1
    Marker Score: 339
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,646
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 0.99
    Marker Score: 47,872
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.99
    Marker Score: 370
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.98
    Marker Score: 1,036
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.98
    Marker Score: 551
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,384
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.98
    Marker Score: 4,227
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.98
    Marker Score: 282
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.96
    Marker Score: 304
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.96
    Marker Score: 15,344
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.95
    Marker Score: 1,150
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.95
    Marker Score: 241
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.94
    Marker Score: 835
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,391
  • Cell Name: fat cell (CL0000136)
    Fold Change: 0.94
    Marker Score: 524
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.93
    Marker Score: 1,899
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.93
    Marker Score: 1,159
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.93
    Marker Score: 478
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.93
    Marker Score: 14,475
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 434
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.91
    Marker Score: 1,295
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.91
    Marker Score: 453
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 0.91
    Marker Score: 1,322
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.9
    Marker Score: 1,468
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.9
    Marker Score: 1,332
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2,694
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.89
    Marker Score: 5,095
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.88
    Marker Score: 357
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.88
    Marker Score: 762
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,294
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.87
    Marker Score: 924
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.87
    Marker Score: 2,082
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.87
    Marker Score: 799
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.87
    Marker Score: 508
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.87
    Marker Score: 315
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.87
    Marker Score: 934
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 308
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 0.85
    Marker Score: 4,478
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.85
    Marker Score: 856
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.85
    Marker Score: 2,302
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.84
    Marker Score: 903
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.84
    Marker Score: 4,540
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.84
    Marker Score: 1,089
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.83
    Marker Score: 2,056
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.82
    Marker Score: 316
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 0.82
    Marker Score: 1,431
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.82
    Marker Score: 866
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.82
    Marker Score: 1,922
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.81
    Marker Score: 18,132
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.81
    Marker Score: 293
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.81
    Marker Score: 163
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.81
    Marker Score: 323
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.8
    Marker Score: 1,834
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.8
    Marker Score: 2,759
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.8
    Marker Score: 278
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.8
    Marker Score: 191
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.8
    Marker Score: 759

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** TNPO3 is a small, acidic protein that belongs to the importin family. It has a molecular weight of approximately 12 kDa and is characterized by its ability to bind to nuclear localization signals (NLS) and facilitate the transport of proteins into the nucleus. TNPO3 is highly conserved across species, with high sequence homology to other importins, suggesting its essential role in cellular processes. **Pathways and Functions:** TNPO3 is involved in several key pathways, including: 1. **Protein Import into the Nucleus:** TNPO3 binds to NLS-containing proteins and facilitates their transport into the nucleus, where they can regulate gene expression and transcription. 2. **Regulation of Gene Expression:** TNPO3 plays a role in the regulation of gene expression by importing transcription factors and other nuclear proteins that are essential for the transcriptional machinery. 3. **Maintenance of Genome Stability:** TNPO3 is involved in the regulation of DNA replication and repair, ensuring the integrity of the genome. 4. **Cell Cycle Regulation:** TNPO3 is also involved in the regulation of the cell cycle, ensuring proper progression through the cell cycle phases. **Significantly Expressed Cells:** TNPO3 is highly expressed in various cell types, including: 1. **Corneal Epithelial Cells:** TNPO3 is essential for maintaining the integrity of the corneal epithelium. 2. **Neural Cells:** TNPO3 is highly expressed in neural cells, including glutamatergic and GABAergic neurons, suggesting its role in neuronal development and function. 3. **Dopaminergic Neurons:** TNPO3 is also expressed in dopaminergic neurons, suggesting its involvement in the regulation of dopamine signaling. **Proteins Associated with TNPO3:** TNPO3 interacts with various proteins, including: 1. **B3KMX1:** A protein that interacts with TNPO3 and is involved in the regulation of protein import into the nucleus. **Clinical Significance:** Dysregulation of TNPO3 has been implicated in various diseases, including: 1. **Cancer:** TNPO3 has been shown to be overexpressed in certain types of cancer, suggesting its potential role in tumorigenesis. 2. **Neurodegenerative Diseases:** TNPO3 has been implicated in the regulation of gene expression in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. 3. **Infectious Diseases:** TNPO3 has been shown to be involved in the regulation of gene expression in response to viral infections. In conclusion, TNPO3 is a crucial protein involved in various cellular processes, including protein import into the nucleus, regulation of gene expression, and maintenance of genome stability. Its dysregulation has been implicated in various diseases, highlighting the importance of TNPO3 in maintaining cellular homeostasis. Further research is needed to fully elucidate the role of TNPO3 in disease pathology and to explore its potential as a therapeutic target.

Genular Protein ID: 3919634247

Symbol: TNPO3_HUMAN

Name: Importin-12

UniProtKB Accession Codes:

Q9Y5L0 A4D1K9 C9IZM0 Q6NUM1 Q96G71 Q96GU9 Q9Y3R2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 4 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 14 PDBsum 5 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10366588

Title: Transportin-SR, a nuclear import receptor for SR proteins.

PubMed ID: 10366588

DOI: 10.1083/jcb.145.6.1145

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10713112

Title: A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins.

PubMed ID: 10713112

DOI: 10.1074/jbc.275.11.7950

PubMed ID: 11517331

Title: Transportin-SR2 mediates nuclear import of phosphorylated SR proteins.

PubMed ID: 11517331

DOI: 10.1073/pnas.181354098

PubMed ID: 12628928

Title: A novel splicing regulator shares a nuclear import pathway with SR proteins.

PubMed ID: 12628928

DOI: 10.1093/emboj/cdg126

PubMed ID: 18722123

Title: Transportin-SR2 imports HIV into the nucleus.

PubMed ID: 18722123

DOI: 10.1016/j.cub.2008.07.079

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21901095

Title: Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration.

PubMed ID: 21901095

DOI: 10.1371/journal.ppat.1002194

PubMed ID: 22398280

Title: TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core.

PubMed ID: 22398280

DOI: 10.1128/jvi.00451-12

PubMed ID: 23878195

Title: Interaction of transportin-SR2 with Ras-related nuclear protein (Ran) GTPase.

PubMed ID: 23878195

DOI: 10.1074/jbc.m113.484345

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23667635

Title: Next-generation sequencing identifies transportin 3 as the causative gene for LGMD1F.

PubMed ID: 23667635

DOI: 10.1371/journal.pone.0063536

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28356354

Title: N-terminal half of transportin SR2 interacts with HIV integrase.

PubMed ID: 28356354

DOI: 10.1074/jbc.m117.777029

PubMed ID: 29329553

Title: Inhibitors of the integrase-transportin-SR2 interaction block HIV nuclear import.

PubMed ID: 29329553

DOI: 10.1186/s12977-018-0389-2

PubMed ID: 31465518

Title: The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection.

PubMed ID: 31465518

DOI: 10.1371/journal.ppat.1007958

PubMed ID: 24915079

Title: Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran.

PubMed ID: 24915079

DOI: 10.1107/s2053230x14009492

PubMed ID: 24449914

Title: Structural basis for nuclear import of splicing factors by human Transportin 3.

PubMed ID: 24449914

DOI: 10.1073/pnas.1320755111

PubMed ID: 30916345

Title: Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6.

PubMed ID: 30916345

DOI: 10.1093/nar/gkz206

PubMed ID: 23543484

Title: Limb-girdle muscular dystrophy 1F is caused by a microdeletion in the transportin 3 gene.

PubMed ID: 23543484

DOI: 10.1093/brain/awt074

PubMed ID: 31071488

Title: A novel pathogenic variant in TNPO3 in a Hungarian family with limb-girdle muscular dystrophy 1F.

PubMed ID: 31071488

DOI: 10.1016/j.ejmg.2019.05.001

PubMed ID: 31192305

Title: Novel mutation in TNPO3 causes congenital limb-girdle myopathy with slow progression.

PubMed ID: 31192305

DOI: 10.1212/nxg.0000000000000337

Sequence Information:

  • Length: 923
  • Mass: 104203
  • Checksum: CF7CDC14CDBA56AB
  • Sequence:
    • MEGAKPTLQL VYQAVQALYH DPDPSGKERA SFWLGELQRS VHAWEISDQL LQIRQDVESC 
YFAAQTMKMK IQTSFYELPT DSHASLRDSL LTHIQNLKDL SPVIVTQLAL AIADLALQMP 
SWKGCVQTLV EKYSNDVTSL PFLLEILTVL PEEVHSRSLR IGANRRTEII EDLAFYSSTV 
VSLLMTCVEK AGTDEKMLMK VFRCLGSWFN LGVLDSNFMA NNKLLALLFE VLQQDKTSSN 
LHEAASDCVC SALYAIENVE TNLPLAMQLF QGVLTLETAY HMAVAREDLD KVLNYCRIFT 
ELCETFLEKI VCTPGQGLGD LRTLELLLIC AGHPQYEVVE ISFNFWYRLG EHLYKTNDEV 
IHGIFKAYIQ RLLHALARHC QLEPDHEGVP EETDDFGEFR MRVSDLVKDL IFLIGSMECF 
AQLYSTLKEG NPPWEVTEAV LFIMAAIAKS VDPENNPTLV EVLEGVVRLP ETVHTAVRYT 
SIELVGEMSE VVDRNPQFLD PVLGYLMKGL CEKPLASAAA KAIHNICSVC RDHMAQHFNG 
LLEIARSLDS FLLSPEAAVG LLKGTALVLA RLPLDKITEC LSELCSVQVM ALKKLLSQEP 
SNGISSDPTV FLDRLAVIFR HTNPIVENGQ THPCQKVIQE IWPVLSETLN KHRADNRIVE 
RCCRCLRFAV RCVGKGSAAL LQPLVTQMVN VYHVHQHSCF LYLGSILVDE YGMEEGCRQG 
LLDMLQALCI PTFQLLEQQN GLQNHPDTVD DLFRLATRFI QRSPVTLLRS QVVIPILQWA 
IASTTLDHRD ANCSVMRFLR DLIHTGVAND HEEDFELRKE LIGQVMNQLG QQLVSQLLHT 
CCFCLPPYTL PDVAEVLWEI MQVDRPTFCR WLENSLKGLP KETTVGAVTV THKQLTDFHK 
QVTSAEECKQ VCWALRDFTR LFR

Genular Protein ID: 3502713196

Symbol: B3KMX1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KMX1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 2 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 480
  • Mass: 53946
  • Checksum: E1BD57FB9E48AE79
  • Sequence:
    • MAAIAKSVDP ENNPTLVEVL EGVVRLPETV HTAVRYTSIE LVGEMSEVVD RNPQFLDPVL 
GYLMKGLCEK PLASAAAKAI HNICSVCRDH MAQHFNGLLE IARSLDSFLL SPEAAVGLLK 
GTALVLARLP LDKITECLSE LCSVQVMALK KLLSQEPSNG ISSDPTVFLD RLAVIFRHTN 
PIVENGQTHP CQKVIQEIWP VLSETLNKHR ADNRIVERCC RCLRFAVRCV GKGSAALLQP 
LVTQMVNVYH VHQHSCFLYL GSILVDEYGM EEGCRQGLLD MLQALCIPTF QLLEQQNGLQ 
NHPDTVDDLF RLATRFIQRS PVTLLRSQVV IPILQWAIAS TTLDHRDANC SVMRFLRDLI 
HTGVANDHEE DFELRKELIG QVMNQLGQQL VSQLLHTCCF CLPPYTLPDV AEVLWEIMQV 
DRPTFCRWLE NSLKGLPKET TVGAVTVTHK QLTDFHKQVT SAEECKQVCW ALRDFTRLFR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.