Details for: ATP6V0A2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 1.27
Marker Score: 408 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.25
Marker Score: 1,924 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.14
Marker Score: 9,803 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.12
Marker Score: 10,575 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.11
Marker Score: 41,021 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.06
Marker Score: 10,928 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.05
Marker Score: 64,381 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.03
Marker Score: 39,023 - Cell Name: neuron (CL0000540)
Fold Change: 1.02
Marker Score: 4,142 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.01
Marker Score: 9,598 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,719 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,943 - Cell Name: interneuron (CL0000099)
Fold Change: 0.99
Marker Score: 454 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,396 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,398 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.92
Marker Score: 476 - Cell Name: basophil (CL0000767)
Fold Change: 0.92
Marker Score: 438 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.91
Marker Score: 432 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,707 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.9
Marker Score: 823 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,292 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.87
Marker Score: 1,092 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.86
Marker Score: 3,555 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.85
Marker Score: 12,746 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.85
Marker Score: 4,857 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.85
Marker Score: 16,928 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 305 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.82
Marker Score: 3,181 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 0.82
Marker Score: 286 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 0.81
Marker Score: 587 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.8
Marker Score: 546 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.79
Marker Score: 1,794 - Cell Name: mast cell (CL0000097)
Fold Change: 0.79
Marker Score: 456 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.78
Marker Score: 5,996 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.77
Marker Score: 1,256 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.76
Marker Score: 304 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.75
Marker Score: 834 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.75
Marker Score: 2,580 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.75
Marker Score: 785 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.74
Marker Score: 562 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.73
Marker Score: 11,480 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.72
Marker Score: 252 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.72
Marker Score: 207 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 371 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.69
Marker Score: 517 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.68
Marker Score: 2,851 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.68
Marker Score: 284 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.68
Marker Score: 14,447 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 172 - Cell Name: brush cell (CL0002204)
Fold Change: 0.66
Marker Score: 602 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.65
Marker Score: 173 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.65
Marker Score: 314 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.65
Marker Score: 641 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.64
Marker Score: 400 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.63
Marker Score: 431 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.63
Marker Score: 1,387 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.62
Marker Score: 1,257 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.61
Marker Score: 881 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.6
Marker Score: 384 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.6
Marker Score: 396 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.59
Marker Score: 684 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.59
Marker Score: 239 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.58
Marker Score: 158 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.58
Marker Score: 304 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.57
Marker Score: 335 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.57
Marker Score: 390 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 0.57
Marker Score: 111 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.57
Marker Score: 611 - Cell Name: Unknown (CL0000548)
Fold Change: 0.57
Marker Score: 413 - Cell Name: granulocyte (CL0000094)
Fold Change: 0.56
Marker Score: 250 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.56
Marker Score: 332 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.56
Marker Score: 225 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.55
Marker Score: 1,307 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.55
Marker Score: 315 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.55
Marker Score: 1,313 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 0.55
Marker Score: 255 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.54
Marker Score: 317 - Cell Name: eosinophil (CL0000771)
Fold Change: 0.54
Marker Score: 176 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.54
Marker Score: 28,536 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 0.54
Marker Score: 4,654 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.53
Marker Score: 426 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.53
Marker Score: 521 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.53
Marker Score: 752 - Cell Name: podocyte (CL0000653)
Fold Change: 0.53
Marker Score: 195 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.53
Marker Score: 118 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.53
Marker Score: 707 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.53
Marker Score: 351 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 0.52
Marker Score: 1,655 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.52
Marker Score: 153 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.52
Marker Score: 181 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.52
Marker Score: 2,182 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.52
Marker Score: 451 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 0.52
Marker Score: 252 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.51
Marker Score: 436 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 0.51
Marker Score: 401 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 0.51
Marker Score: 554 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.51
Marker Score: 164 - Cell Name: dendritic cell (CL0000451)
Fold Change: 0.51
Marker Score: 348 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.51
Marker Score: 212 - Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
Fold Change: 0.51
Marker Score: 112
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1417427081
Symbol: VPP2_HUMAN
Name: V-type proton ATPase 116 kDa subunit a 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16415858
Title: V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway.
PubMed ID: 16415858
DOI: 10.1038/ncb1348
PubMed ID: 17295899
Title: The N-terminal domain of the a2 isoform of vacuolar ATPase can regulate interleukin-1beta production from mononuclear cells in co-culture with JEG-3 choriocarcinoma cells.
PubMed ID: 17295899
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18157129
Title: Impaired glycosylation and cutis laxa caused by mutations in the vesicular H+-ATPase subunit ATP6V0A2.
PubMed ID: 18157129
DOI: 10.1038/ng.2007.45
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 28296633
Title: The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1alpha prolyl hydroxylation by regulating cellular iron levels.
PubMed ID: 28296633
DOI: 10.7554/elife.22693
PubMed ID: 28024296
Title: mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.
PubMed ID: 28024296
DOI: 10.1038/nature21034
Sequence Information:
- Length: 856
- Mass: 98082
- Checksum: 6C38B36FA33A92BA
- Sequence:
MGSLFRSETM CLAQLFLQSG TAYECLSALG EKGLVQFRDL NQNVSSFQRK FVGEVKRCEE LERILVYLVQ EINRADIPLP EGEASPPAPP LKQVLEMQEQ LQKLEVELRE VTKNKEKLRK NLLELIEYTH MLRVTKTFVK RNVEFEPTYE EFPSLESDSL LDYSCMQRLG AKLGFVSGLI NQGKVEAFEK MLWRVCKGYT IVSYAELDES LEDPETGEVI KWYVFLISFW GEQIGHKVKK ICDCYHCHVY PYPNTAEERR EIQEGLNTRI QDLYTVLHKT EDYLRQVLCK AAESVYSRVI QVKKMKAIYH MLNMCSFDVT NKCLIAEVWC PEADLQDLRR ALEEGSRESG ATIPSFMNII PTKETPPTRI RTNKFTEGFQ NIVDAYGVGS YREVNPALFT IITFPFLFAV MFGDFGHGFV MFLFALLLVL NENHPRLNQS QEIMRMFFNG RYILLLMGLF SVYTGLIYND CFSKSVNLFG SGWNVSAMYS SSHPPAEHKK MVLWNDSVVR HNSILQLDPS IPGVFRGPYP LGIDPIWNLA TNRLTFLNSF KMKMSVILGI IHMTFGVILG IFNHLHFRKK FNIYLVSIPE LLFMLCIFGY LIFMIFYKWL VFSAETSRVA PSILIEFINM FLFPASKTSG LYTGQEYVQR VLLVVTALSV PVLFLGKPLF LLWLHNGRSC FGVNRSGYTL IRKDSEEEVS LLGSQDIEEG NHQVEDGCRE MACEEFNFGE ILMTQVIHSI EYCLGCISNT ASYLRLWALS LAHAQLSDVL WAMLMRVGLR VDTTYGVLLL LPVIALFAVL TIFILLIMEG LSAFLHAIRL HWVEFQNKFY VGAGTKFVPF SFSLLSSKFN NDDSVA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.