ARL2BP | ENSG00000102931 | NCBI 23568

Details for: ARL2BP

Gene ID: 23568

Symbol: ARL2BP

Ensembl ID: ENSG00000102931

Description: ADP ribosylation factor like GTPase 2 binding protein

Associated with

Slc-mediated transmembrane transport
(R-HSA-425407)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
(R-HSA-83936)
Transport of small molecules
(R-HSA-382551)
Transport of vitamins, nucleosides, and related molecules
(R-HSA-425397)
Centrosome
(GO:0005813)
Cilium
(GO:0005929)
Cytosol
(GO:0005829)
Gtpase regulator activity
(GO:0030695)
Maintenance of protein location in nucleus
(GO:0051457)
Midbody
(GO:0030496)
Mitochondrial intermembrane space
(GO:0005758)
Mitochondrial matrix
(GO:0005759)
Nucleoplasm
(GO:0005654)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of tyrosine phosphorylation of stat protein
(GO:0042531)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)
Spindle
(GO:0005819)
Transcription coactivator activity
(GO:0003713)

Other Information

Proteins

ADP-ribosylation factor-like protein 2-binding protein

Genular Protein ID: 2515556556

Symbol: AR2BP_HUMAN

Name: ADP-ribosylation factor-like protein 2-binding protein

UniProtKB Accession Codes:

Q9Y2Y0 B3KQJ5 Q504R0

Database IDs:

Citations:

PubMed ID: 10488091

Title: The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization.

PubMed ID: 10488091

DOI: 10.1074/jbc.274.39.27553

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11303027

Title: ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins.

PubMed ID: 11303027

DOI: 10.1074/jbc.m102359200

PubMed ID: 11847227

Title: Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C.

PubMed ID: 11847227

DOI: 10.1074/jbc.m200128200

PubMed ID: 11809823

Title: ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter.

PubMed ID: 11809823

DOI: 10.1091/mbc.01-05-0245

PubMed ID: 16525022

Title: Arl2 and Arl3 regulate different microtubule-dependent processes.

PubMed ID: 16525022

DOI: 10.1091/mbc.e05-10-0929

PubMed ID: 18234692

Title: BART is essential for nuclear retention of STAT3.

PubMed ID: 18234692

DOI: 10.1093/intimm/dxm154

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 27790702

Title: ARL2BP mutations account for 0.1% of autosomal recessive rod-cone dystrophies with the report of a novel splice variant.

PubMed ID: 27790702

DOI: 10.1111/cge.12909

PubMed ID: 18981177

Title: The structure of binder of Arl2 (BART) reveals a novel G protein binding domain: implications for function.

PubMed ID: 18981177

DOI: 10.1074/jbc.m806167200

PubMed ID: 30945270

Title: Whole-exome sequencing identified ARL2 as a novel candidate gene for MRCS (microcornea, rod-cone dystrophy, cataract, and posterior staphyloma) syndrome.

PubMed ID: 30945270

DOI: 10.1111/cge.13541

PubMed ID: 19368893

Title: Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector.

PubMed ID: 19368893

DOI: 10.1016/j.str.2009.01.014

PubMed ID: 23849777

Title: Mutations in ARL2BP, encoding ADP-ribosylation-factor-like 2 binding protein, cause autosomal-recessive retinitis pigmentosa.

PubMed ID: 23849777

DOI: 10.1016/j.ajhg.2013.06.003

Sequence Information:

Length: 163
Mass: 18822
Checksum: E35EB5AC73FC1FEC
Sequence:

MDALEGESFA LSFSSASDAE FDAVVGYLED IIMDDEFQLL QRNFMDKYYL EFEDTEENKL 
IYTPIFNEYI SLVEKYIEEQ LLQRIPEFNM AAFTTTLQHH KDEVAGDIFD MLLTFTDFLA 
FKEMFLDYRA EKEGRGLDLS SGLVVTSLCK SSSLPASQNN LRH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ARL2BP

Associated with

Other Information

The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization. PubMed ID: 10488091

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins. PubMed ID: 11303027

Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C. PubMed ID: 11847227

ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter. PubMed ID: 11809823

Arl2 and Arl3 regulate different microtubule-dependent processes. PubMed ID: 16525022

BART is essential for nuclear retention of STAT3. PubMed ID: 18234692

Initial characterization of the human central proteome. PubMed ID: 21269460

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

ARL2BP mutations account for 0.1% of autosomal recessive rod-cone dystrophies with the report of a novel splice variant. PubMed ID: 27790702

The structure of binder of Arl2 (BART) reveals a novel G protein binding domain: implications for function. PubMed ID: 18981177

Whole-exome sequencing identified ARL2 as a novel candidate gene for MRCS (microcornea, rod-cone dystrophy, cataract, and posterior staphyloma) syndrome. PubMed ID: 30945270

Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector. PubMed ID: 19368893

Mutations in ARL2BP, encoding ADP-ribosylation-factor-like 2 binding protein, cause autosomal-recessive retinitis pigmentosa. PubMed ID: 23849777