PATZ1 | ENSG00000100105 | NCBI 23598

Details for: PATZ1

Gene ID: 23598

Symbol: PATZ1

Ensembl ID: ENSG00000100105

Description: POZ/BTB and AT hook containing zinc finger 1

Associated with

Chromatin binding
(GO:0003682)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Male germ cell nucleus
(GO:0001673)
Male gonad development
(GO:0008584)
Metal ion binding
(GO:0046872)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of endothelial cell migration
(GO:0010596)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription
(GO:0045893)
Protein binding
(GO:0005515)
Regulation of cytokine production
(GO:0001817)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of immune system process
(GO:0002682)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Spermatogenesis
(GO:0007283)
T cell differentiation
(GO:0030217)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

POZ-, AT hook-, and zinc finger-containing protein 1

Genular Protein ID: 4131357072

Symbol: PATZ1_HUMAN

Name: POZ-, AT hook-, and zinc finger-containing protein 1

UniProtKB Accession Codes:

Q9HBE1 Q9HBE2 Q9HBE3 Q9P1A9 Q9UDU0 Q9Y529

Database IDs:

Citations:

PubMed ID: 10713105

Title: A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor.

PubMed ID: 10713105

DOI: 10.1074/jbc.275.11.7894

PubMed ID: 10949935

Title: A novel zinc finger gene is fused to EWS in small round cell tumor.

PubMed ID: 10949935

DOI: 10.1038/sj.onc.1203762

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25755280

Title: PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function.

PubMed ID: 25755280

DOI: 10.1128/mcb.01475-14

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 31875552

Title: The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells.

PubMed ID: 31875552

DOI: 10.1016/j.celrep.2019.11.089

PubMed ID: 31060775

Title: PATZ1 is required for efficient HIV-1 infection.

PubMed ID: 31060775

DOI: 10.1016/j.bbrc.2019.04.175

Sequence Information:

Length: 687
Mass: 74060
Checksum: 0F1C59A78C6D110A
Sequence:

MERVNDASCG PSGCYTYQVS RHSTEMLHNL NQQRKNGGRF CDVLLRVGDE SFPAHRAVLA 
ACSEYFESVF SAQLGDGGAA DGGPADVGGA TAAPGGGAGG SRELEMHTIS SKVFGDILDF 
AYTSRIVVRL ESFPELMTAA KFLLMRSVIE ICQEVIKQSN VQILVPPARA DIMLFRPPGT 
SDLGFPLDMT NGAALAANSN GIAGSMQPEE EAARAAGAAI AGQASLPVLP GVDRLPMVAG 
PLSPQLLTSP FPSVASSAPP LTGKRGRGRP RKANLLDSMF GSPGGLREAG ILPCGLCGKV 
FTDANRLRQH EAQHGVTSLQ LGYIDLPPPR LGENGLPISE DPDGPRKRSR TRKQVACEIC 
GKIFRDVYHL NRHKLSHSGE KPYSCPVCGL RFKRKDRMSY HVRSHDGSVG KPYICQSCGK 
GFSRPDHLNG HIKQVHTSER PHKCQTCNAS FATRDRLRSH LACHEDKVPC QVCGKYLRAA 
YMADHLKKHS EGPSNFCSIC NRGFSSASYL KVHVKTHHGV PLPQVSRHQE PILNGGAAFH 
CARTYGNKEG QKCSHQDPIE SSDSYGDLSD ASDLKTPEKQ SANGSFSCDM AVPKNKMESD 
GEKKYPCPEC GSFFRSKSYL NKHIQKVHVR ALGGPLGDLG PALGSPFSPQ QNMSLLESFG 
FQIVQSAFAS SLVDPEVDQQ PMGPEGK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: PATZ1

Associated with

Other Information

A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor. PubMed ID: 10713105

A novel zinc finger gene is fused to EWS in small round cell tumor. PubMed ID: 10949935

A genome annotation-driven approach to cloning the human ORFeome. PubMed ID: 15461802

The DNA sequence of human chromosome 22. PubMed ID: 10591208

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function. PubMed ID: 25755280

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. PubMed ID: 31875552

PATZ1 is required for efficient HIV-1 infection. PubMed ID: 31060775