Details for: TSSK2

Gene ID: 23617

Symbol: TSSK2

Ensembl ID: ENSG00000206203

Description: testis specific serine kinase 2

Associated with

Other Information

Genular Protein ID: 95271579

Symbol: TSSK2_HUMAN

Name: Testis-specific serine/threonine-protein kinase 2

UniProtKB Accession Codes:

Q96PF2 Q8IY55

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 13 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 Rhea 6 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8776594

Title: A transcription map of the DiGeorge and velo-cardio-facial syndrome minimal critical region on 22q11.

PubMed ID: 8776594

DOI: 10.1093/hmg/5.6.789

PubMed ID: 15044604

Title: Expression analysis of the human testis-specific serine/threonine kinase (TSSK) homologues. A TSSK member is present in the equatorial segment of human sperm.

PubMed ID: 15044604

DOI: 10.1093/molehr/gah052

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17566264

Title: Validation of a testis specific serine/threonine kinase [TSSK] family and the substrate of TSSK1 & 2, TSKS, as contraceptive targets.

PubMed ID: 17566264

PubMed ID: 18495105

Title: TSKS concentrates in spermatid centrioles during flagellogenesis.

PubMed ID: 18495105

DOI: 10.1016/j.ydbio.2008.03.043

PubMed ID: 18533145

Title: Targeted deletion of Tssk1 and 2 causes male infertility due to haploinsufficiency.

PubMed ID: 18533145

DOI: 10.1016/j.ydbio.2008.03.047

PubMed ID: 20729278

Title: Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testis.

PubMed ID: 20729278

DOI: 10.1093/molehr/gaq071

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 19926886

Title: Some single-nucleotide polymorphisms of the TSSK2 gene may be associated with human spermatogenesis impairment.

PubMed ID: 19926886

DOI: 10.2164/jandrol.109.008466

Sequence Information:

  • Length: 358
  • Mass: 40939
  • Checksum: F231433AA78B2FE9
  • Sequence:
    • MDDATVLRKK GYIVGINLGK GSYAKVKSAY SERLKFNVAV KIIDRKKTPT DFVERFLPRE 
MDILATVNHG SIIKTYEIFE TSDGRIYIIM ELGVQGDLLE FIKCQGALHE DVARKMFRQL 
SSAVKYCHDL DIVHRDLKCE NLLLDKDFNI KLSDFGFSKR CLRDSNGRII LSKTFCGSAA 
YAAPEVLQSI PYQPKVYDIW SLGVILYIMV CGSMPYDDSD IRKMLRIQKE HRVDFPRSKN 
LTCECKDLIY RMLQPDVSQR LHIDEILSHS WLQPPKPKAT SSASFKREGE GKYRAECKLD 
TKTGLRPDHR PDHKLGAKTQ HRLLVVPENE NRMEDRLAET SRAKDHHISG AEVGKAST

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.