Details for: PRND
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 4.99
Marker Score: 2,625 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 2.22
Marker Score: 930 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.92
Marker Score: 2,792 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.68
Marker Score: 1,578 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.38
Marker Score: 877 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 1.3
Marker Score: 7,699 - Cell Name: goblet cell (CL0000160)
Fold Change: 1.16
Marker Score: 7,693 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251,820 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,837 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,062 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 1
Marker Score: 2,064 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,409 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.98
Marker Score: 2,478 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5,354 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2,743 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.89
Marker Score: 681 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,291 - Cell Name: mast cell (CL0000097)
Fold Change: 0.82
Marker Score: 477 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 712 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,266 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.77
Marker Score: 401 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.75
Marker Score: 496 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.74
Marker Score: 1,507 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.71
Marker Score: 181 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.68
Marker Score: 721 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.63
Marker Score: 503 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.57
Marker Score: 150 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.53
Marker Score: 8,277 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.47
Marker Score: 281 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.45
Marker Score: 145 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.45
Marker Score: 431 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.43
Marker Score: 247 - Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: 0.41
Marker Score: 412 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.39
Marker Score: 732 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.37
Marker Score: 376 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.34
Marker Score: 575 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.27
Marker Score: 160 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.26
Marker Score: 617 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.26
Marker Score: 200 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.24
Marker Score: 224 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.23
Marker Score: 123 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.23
Marker Score: 102 - Cell Name: monocyte (CL0000576)
Fold Change: 0.23
Marker Score: 297 - Cell Name: erythrocyte (CL0000232)
Fold Change: 0.22
Marker Score: 122 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: 0.22
Marker Score: 51 - Cell Name: T cell (CL0000084)
Fold Change: 0.21
Marker Score: 360 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 0.18
Marker Score: 126 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.18
Marker Score: 181 - Cell Name: endothelial cell of artery (CL1000413)
Fold Change: 0.17
Marker Score: 72 - Cell Name: vein endothelial cell (CL0002543)
Fold Change: 0.17
Marker Score: 154 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.16
Marker Score: 59 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.16
Marker Score: 50 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.15
Marker Score: 73 - Cell Name: pericyte (CL0000669)
Fold Change: 0.13
Marker Score: 75 - Cell Name: B cell (CL0000236)
Fold Change: 0.13
Marker Score: 121 - Cell Name: podocyte (CL0000653)
Fold Change: 0.12
Marker Score: 45 - Cell Name: plasma cell (CL0000786)
Fold Change: 0.11
Marker Score: 127 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.11
Marker Score: 38 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.1
Marker Score: 90 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.1
Marker Score: 26 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.1
Marker Score: 65 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.09
Marker Score: 95 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.08
Marker Score: 34 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.08
Marker Score: 81 - Cell Name: neutrophil (CL0000775)
Fold Change: 0.08
Marker Score: 51 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.08
Marker Score: 25 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.07
Marker Score: 30 - Cell Name: dendritic cell (CL0000451)
Fold Change: 0.06
Marker Score: 40 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.06
Marker Score: 38 - Cell Name: respiratory basal cell (CL0002633)
Fold Change: 0.06
Marker Score: 82 - Cell Name: club cell (CL0000158)
Fold Change: 0.05
Marker Score: 63 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.05
Marker Score: 101 - Cell Name: macrophage (CL0000235)
Fold Change: 0.05
Marker Score: 58 - Cell Name: mature NK T cell (CL0000814)
Fold Change: 0.05
Marker Score: 24 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: 0.05
Marker Score: 38 - Cell Name: plasmacytoid dendritic cell (CL0000784)
Fold Change: 0.05
Marker Score: 26 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 0.05
Marker Score: 48 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.05
Marker Score: 12 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.05
Marker Score: 65 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.04
Marker Score: 29 - Cell Name: neural cell (CL0002319)
Fold Change: 0.04
Marker Score: 21 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 0.04
Marker Score: 82 - Cell Name: leukocyte (CL0000738)
Fold Change: 0.04
Marker Score: 24 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.04
Marker Score: 66 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.04
Marker Score: 48 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.04
Marker Score: 2,204 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 0.04
Marker Score: 18 - Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 0.04
Marker Score: 14 - Cell Name: epithelial cell of thymus (CL0002293)
Fold Change: 0.04
Marker Score: 12 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 0.04
Marker Score: 47 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.04
Marker Score: 13 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.04
Marker Score: 12 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.03
Marker Score: 14 - Cell Name: Unknown (CL0000003)
Fold Change: 0.03
Marker Score: 107 - Cell Name: basal cell (CL0000646)
Fold Change: 0.03
Marker Score: 44 - Cell Name: gut endothelial cell (CL0000131)
Fold Change: 0.03
Marker Score: 12 - Cell Name: memory T cell (CL0000813)
Fold Change: 0.03
Marker Score: 14 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.03
Marker Score: 59 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.03
Marker Score: 1,689 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 0.03
Marker Score: 12
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 667384810
Symbol: PRND_HUMAN
Name: Prion-like protein doppel
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10525406
Title: Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.
PubMed ID: 10525406
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11063595
Title: Expression and structural characterization of the recombinant human doppel protein.
PubMed ID: 11063595
DOI: 10.1021/bi001523m
PubMed ID: 12200435
Title: The human 'prion-like' protein Doppel is expressed in both Sertoli cells and spermatozoa.
PubMed ID: 12200435
PubMed ID: 15218028
Title: Copper(II) binding to the human Doppel protein may mark its functional diversity from the prion protein.
PubMed ID: 15218028
PubMed ID: 20411530
Title: A doppel alpha-helix peptide fragment mimics the copper(II) interactions with the whole protein.
PubMed ID: 20411530
PubMed ID: 12595265
Title: NMR structure of the human doppel protein.
PubMed ID: 12595265
PubMed ID: 10825657
Title: First report of polymorphisms in the prion-like protein gene (PRND): implications for human prion diseases.
PubMed ID: 10825657
PubMed ID: 11702213
Title: Polymorphisms within the prion-like protein gene (Prnd) and their implications in human prion diseases, Alzheimer's disease and other neurological disorders.
PubMed ID: 11702213
Sequence Information:
- Length: 176
- Mass: 20293
- Checksum: A0F41EB0DFEED236
- Sequence:
MRKHLSWWWL ATVCMLLFSH LSAVQTRGIK HRIKWNRKAL PSTAQITEAQ VAENRPGAFI KQGRKLDIDF GAEGNRYYEA NYWQFPDGIH YNGCSEANVT KEAFVTGCIN ATQAANQGEF QKPDNKLHQQ VLWRLVQELC SLKHCEFWLE RGAGLRVTMH QPVLLCLLAL IWLTVK
Genular Protein ID: 875692980
Symbol: A7U7M2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 176
- Mass: 20324
- Checksum: A0F40980DFEED236
- Sequence:
MRKHLSWWWL ATVCMLLFSH LSAVQTRGIK HRIKWNRKAL PSTAQITEAQ VAENRPGAFI KQGRKLDIDF GAEGNRYYEA NYWQFPDGIH YNGCSEANVT KEAFVTGCIN ATQAANQGEF QKPDNKLHQQ VLWRLVQELC SLKHCEFWLE RGAGLRVTMH QPVLLCLLAL IWLMVK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.