Details for: TMEFF2

Gene ID: 23671

Symbol: TMEFF2

Ensembl ID: ENSG00000144339

Description: transmembrane protein with EGF like and two follistatin like domains 2

Associated with

Other Information

Genular Protein ID: 986016170

Symbol: TEFF2_HUMAN

Name: Tomoregulin-2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10903839

Title: Identification and characterization of TMEFF2, a novel survival factor for hippocampal and mesencephalic neurons.

PubMed ID: 10903839

DOI: 10.1006/geno.2000.6228

PubMed ID: 10987305

Title: The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumor cells.

PubMed ID: 10987305

PubMed ID: 11668495

Title: TENB2, a proteoglycan identified in prostate cancer that is associated with disease progression and androgen independence.

PubMed ID: 11668495

DOI: 10.1002/ijc.1450

PubMed ID: 16439095

Title: A truncated isoform of TMEFF2 encodes a secreted protein in prostate cancer cells.

PubMed ID: 16439095

DOI: 10.1016/j.ygeno.2005.12.004

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10600548

Title: A novel epidermal growth factor-like molecule containing two follistatin modules stimulates tyrosine phosphorylation of erbB-4 in MKN28 gastric cancer cells.

PubMed ID: 10600548

DOI: 10.1006/bbrc.1999.1873

PubMed ID: 11120884

Title: HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers.

PubMed ID: 11120884

DOI: 10.1073/pnas.98.1.265

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 16805794

Title: Tomoregulin-2 is found extensively in plaques in Alzheimer's disease brain.

PubMed ID: 16805794

DOI: 10.1111/j.1471-4159.2006.03801.x

PubMed ID: 17942404

Title: Phorbol ester-induced shedding of the prostate cancer marker transmembrane protein with epidermal growth factor and two follistatin motifs 2 is mediated by the disintegrin and metalloproteinase-17.

PubMed ID: 17942404

DOI: 10.1074/jbc.m702170200

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

Sequence Information:

  • Length: 374
  • Mass: 41428
  • Checksum: 44452F680FEBDCDB
  • Sequence:
  • MVLWESPRQC SSWTLCEGFC WLLLLPVMLL IVARPVKLAA FPTSLSDCQT PTGWNCSGYD 
    DRENDLFLCD TNTCKFDGEC LRIGDTVTCV CQFKCNNDYV PVCGSNGESY QNECYLRQAA 
    CKQQSEILVV SEGSCATDAG SGSGDGVHEG SGETSQKETS TCDICQFGAE CDEDAEDVWC 
    VCNIDCSQTN FNPLCASDGK SYDNACQIKE ASCQKQEKIE VMSLGRCQDN TTTTTKSEDG 
    HYARTDYAEN ANKLEESARE HHIPCPEHYN GFCMHGKCEH SINMQEPSCR CDAGYTGQHC 
    EKKDYSVLYV VPGPVRFQYV LIAAVIGTIQ IAVICVVVLC ITRKCPRSNR IHRQKQNTGH 
    YSSDNTTRAS TRLI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.