RAB38 | ENSG00000123892 | NCBI 23682

Details for: RAB38

Gene ID: 23682

Symbol: RAB38

Ensembl ID: ENSG00000123892

Description: RAB38, member RAS oncogene family

Associated with

Membrane trafficking
(R-HSA-199991)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Rab gefs exchange gtp for gdp on rabs
(R-HSA-8876198)
Rab geranylgeranylation
(R-HSA-8873719)
Rab regulation of trafficking
(R-HSA-9007101)
Ap-1 adaptor complex binding
(GO:0035650)
Ap-2 adaptor complex binding
(GO:0035612)
Ap-3 adaptor complex binding
(GO:0035651)
Bloc-2 complex binding
(GO:0036461)
Cell body
(GO:0044297)
Cytosol
(GO:0005829)
Early endosome
(GO:0005769)
Early endosome lumen
(GO:0031905)
Endomembrane system
(GO:0012505)
Endosome to melanosome transport
(GO:0035646)
Gtp-dependent protein binding
(GO:0030742)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Intracellular protein transport
(GO:0006886)
Lysosome
(GO:0005764)
Melanosome
(GO:0042470)
Melanosome assembly
(GO:1903232)
Melanosome membrane
(GO:0033162)
Melanosome organization
(GO:0032438)
Membrane
(GO:0016020)
Mitochondria-associated endoplasmic reticulum membrane
(GO:0044233)
Mitochondrion
(GO:0005739)
Mitochondrion organization
(GO:0007005)
Perinuclear region of cytoplasm
(GO:0048471)
Phagocytic vesicle
(GO:0045335)
Phagocytic vesicle membrane
(GO:0030670)
Phagosome acidification
(GO:0090383)
Plasma membrane
(GO:0005886)
Platelet dense granule organization
(GO:0060155)
Positive regulation of melanin biosynthetic process
(GO:0048023)
Positive regulation of phosphatidylcholine biosynthetic process
(GO:2001247)
Positive regulation of protein localization to cell periphery
(GO:1904377)
Protein binding
(GO:0005515)
Protein localization to membrane
(GO:0072657)
Protein transport
(GO:0015031)
Small gtpase-mediated signal transduction
(GO:0007264)
Trans-golgi network
(GO:0005802)
Vesicle-mediated transport
(GO:0016192)

Other Information

Proteins

Ras-related protein Rab-38

Genular Protein ID: 1758178442

Symbol: RAB38_HUMAN

Name: Ras-related protein Rab-38

UniProtKB Accession Codes:

P57729 Q53XK7

Database IDs:

Citations:

PubMed ID: 10910072

Title: Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library.

PubMed ID: 10910072

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12643545

Title: Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.

PubMed ID: 12643545

DOI: 10.1021/pr025562r

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 17114793

Title: Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation.

PubMed ID: 17114793

DOI: 10.1074/jbc.m605557200

PubMed ID: 19403694

Title: Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes.

PubMed ID: 19403694

DOI: 10.1091/mbc.e08-12-1161

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21255211

Title: Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.

PubMed ID: 21255211

DOI: 10.1111/j.1600-0854.2011.01165.x

PubMed ID: 23084991

Title: BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor.

PubMed ID: 23084991

DOI: 10.1016/j.cub.2012.09.020

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 211
Mass: 23712
Checksum: 0D16B42A1B237539
Sequence:

MQAPHKEHLY KLLVIGDLGV GKTSIIKRYV HQNFSSHYRA TIGVDFALKV LHWDPETVVR 
LQLWDIAGQE RFGNMTRVYY REAMGAFIVF DVTRPATFEA VAKWKNDLDS KLSLPNGKPV 
SVVLLANKCD QGKDVLMNNG LKMDQFCKEH GFVGWFETSA KENINIDEAS RCLVKHILAN 
ECDLMESIEP DVVKPHLTST KVASCSGCAK S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RAB38

Associated with

Other Information

Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library. PubMed ID: 10910072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Proteomic analysis of early melanosomes: identification of novel melanosomal proteins. PubMed ID: 12643545

Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. PubMed ID: 17081065

Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation. PubMed ID: 17114793

Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes. PubMed ID: 19403694

Initial characterization of the human central proteome. PubMed ID: 21269460

Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. PubMed ID: 21255211

BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor. PubMed ID: 23084991

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974