Details for: GSPT2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: respiratory basal cell (CL0002633)
Fold Change: 2.61
Marker Score: 3,745 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.1
Marker Score: 883 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,777 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,001 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,404 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,407 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 485 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 440 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.92
Marker Score: 5,234 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,723 - Cell Name: tracheobronchial smooth muscle cell (CL0019019)
Fold Change: 0.89
Marker Score: 262 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.88
Marker Score: 354 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,265 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 307 - Cell Name: germ cell (CL0000586)
Fold Change: 0.82
Marker Score: 1,439 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,269 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 376 - Cell Name: Mueller cell (CL0000636)
Fold Change: 0.71
Marker Score: 982 - Cell Name: brush cell (CL0002204)
Fold Change: 0.71
Marker Score: 644 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.69
Marker Score: 525 - Cell Name: gut endothelial cell (CL0000131)
Fold Change: 0.68
Marker Score: 245 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.67
Marker Score: 2,797 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 170 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.66
Marker Score: 644 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.64
Marker Score: 151 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.64
Marker Score: 3,818 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.63
Marker Score: 635 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.63
Marker Score: 425 - Cell Name: Unknown (CL0002371)
Fold Change: 0.62
Marker Score: 664 - Cell Name: enteric neuron (CL0007011)
Fold Change: 0.62
Marker Score: 331 - Cell Name: neural cell (CL0002319)
Fold Change: 0.61
Marker Score: 296 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.6
Marker Score: 1,212 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.59
Marker Score: 377 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.58
Marker Score: 318 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.57
Marker Score: 610 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.56
Marker Score: 595 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.55
Marker Score: 314 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.54
Marker Score: 1,134 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 432 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.53
Marker Score: 748 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.53
Marker Score: 177 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.52
Marker Score: 346 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 0.51
Marker Score: 341 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.51
Marker Score: 1,378 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.49
Marker Score: 1,823 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.48
Marker Score: 517 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.48
Marker Score: 500 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.47
Marker Score: 458 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.47
Marker Score: 142 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.47
Marker Score: 1,286 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.47
Marker Score: 4,750 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.46
Marker Score: 579 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.46
Marker Score: 3,005 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.46
Marker Score: 555 - Cell Name: small pre-B-II cell (CL0000954)
Fold Change: 0.45
Marker Score: 545 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.44
Marker Score: 414 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.44
Marker Score: 5,760 - Cell Name: interstitial cell of Cajal (CL0002088)
Fold Change: 0.44
Marker Score: 151 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.44
Marker Score: 411 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.43
Marker Score: 1,749 - Cell Name: myeloid dendritic cell (CL0000782)
Fold Change: 0.43
Marker Score: 258 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.42
Marker Score: 287 - Cell Name: motor neuron (CL0000100)
Fold Change: 0.42
Marker Score: 250 - Cell Name: late pro-B cell (CL0002048)
Fold Change: 0.42
Marker Score: 491 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.42
Marker Score: 110 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.41
Marker Score: 704 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.41
Marker Score: 179 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.41
Marker Score: 189 - Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 0.41
Marker Score: 192 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.4
Marker Score: 167 - Cell Name: endocardial cell (CL0002350)
Fold Change: 0.4
Marker Score: 226 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.4
Marker Score: 91 - Cell Name: common lymphoid progenitor (CL0000051)
Fold Change: 0.39
Marker Score: 269 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.39
Marker Score: 160 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.39
Marker Score: 259 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.38
Marker Score: 110 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.37
Marker Score: 470 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.37
Marker Score: 791 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 0.37
Marker Score: 182 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.36
Marker Score: 156 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.36
Marker Score: 480 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.36
Marker Score: 3,063 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.36
Marker Score: 4,008 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.36
Marker Score: 837 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.36
Marker Score: 187 - Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.35
Marker Score: 90 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.35
Marker Score: 175 - Cell Name: macroglial cell (CL0000126)
Fold Change: 0.35
Marker Score: 805 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.35
Marker Score: 221 - Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 0.35
Marker Score: 112 - Cell Name: adventitial cell (CL0002503)
Fold Change: 0.35
Marker Score: 86 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.34
Marker Score: 360 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.34
Marker Score: 213 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.34
Marker Score: 136 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.34
Marker Score: 5,254 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 0.33
Marker Score: 116 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: 0.33
Marker Score: 184 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.32
Marker Score: 2,097 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.32
Marker Score: 732 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.32
Marker Score: 202
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2456265279
Symbol: ERF3B_HUMAN
Name: Eukaryotic peptide chain release factor GTP-binding subunit ERF3B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11524954
Title: Identification of a novel termination release factor eRF3b expressing the eRF3 activity in vitro and in vivo.
PubMed ID: 11524954
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15987998
Title: Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation.
PubMed ID: 15987998
PubMed ID: 16721809
Title: Transcriptional census of 36 microdissected colorectal cancers yields a gene signature to distinguish UICC II and III.
PubMed ID: 16721809
DOI: 10.1002/ijc.22027
PubMed ID: 17562865
Title: Human eukaryotic release factor 3a depletion causes cell cycle arrest at G1 phase through inhibition of the mTOR pathway.
PubMed ID: 17562865
DOI: 10.1128/mcb.00035-07
PubMed ID: 18447585
Title: A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay.
PubMed ID: 18447585
PubMed ID: 19417104
Title: SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.
PubMed ID: 19417104
DOI: 10.1101/gad.1767209
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 20418951
Title: Molecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding protein.
PubMed ID: 20418951
Sequence Information:
- Length: 628
- Mass: 68883
- Checksum: 909FCDEF04EC89C9
- Sequence:
MDSGSSSSDS APDCWDQVDM ESPGSAPSGD GVSSAVAEAQ REPLSSAFSR KLNVNAKPFV PNVHAAEFVP SFLRGPTQPP TLPAGSGSND ETCTGAGYPQ GKRMGRGAPV EPSREEPLVS LEGSNSAVTM ELSEPVVENG EVEMALEESW EHSKEVSEAE PGGGSSGDSG PPEESGQEMM EEKEEIRKSK SVIVPSGAPK KEHVNVVFIG HVDAGKSTIG GQIMFLTGMV DKRTLEKYER EAKEKNRETW YLSWALDTNQ EERDKGKTVE VGRAYFETER KHFTILDAPG HKSFVPNMIG GASQADLAVL VISARKGEFE TGFEKGGQTR EHAMLAKTAG VKHLIVLINK MDDPTVNWSI ERYEECKEKL VPFLKKVGFS PKKDIHFMPC SGLTGANIKE QSDFCPWYTG LPFIPYLDNL PNFNRSIDGP IRLPIVDKYK DMGTVVLGKL ESGSIFKGQQ LVMMPNKHNV EVLGILSDDT ETDFVAPGEN LKIRLKGIEE EEILPGFILC DPSNLCHSGR TFDVQIVIIE HKSIICPGYN AVLHIHTCIE EVEITALISL VDKKSGEKSK TRPRFVKQDQ VCIARLRTAG TICLETFKDF PQMGRFTLRD EGKTIAIGKV LKLVPEKD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.