Details for: GABARAPL1
Associated with
Other Information
Genular Protein ID: 4264757766
Symbol: GBRL1_HUMAN
Name: Early estrogen-regulated protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11374880
Title: A novel early estrogen-regulated gene gec1 encodes a protein related to GABARAP.
PubMed ID: 11374880
PubMed ID: 11414770
Title: Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein.
PubMed ID: 11414770
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16431922
Title: GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor.
PubMed ID: 16431922
PubMed ID: 17580304
Title: p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.
PubMed ID: 17580304
PubMed ID: 20404487
Title: GABARAPL1 (GEC1) associates with autophagic vesicles.
PubMed ID: 20404487
PubMed ID: 20562859
Title: Network organization of the human autophagy system.
PubMed ID: 20562859
DOI: 10.1038/nature09204
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22948227
Title: MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins.
PubMed ID: 22948227
DOI: 10.4161/auto.21857
PubMed ID: 23043107
Title: ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.
PubMed ID: 23043107
PubMed ID: 22354992
Title: Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.
PubMed ID: 22354992
DOI: 10.1128/mcb.06717-11
PubMed ID: 22470510
Title: DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.
PubMed ID: 22470510
PubMed ID: 23112293
Title: The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation.
PubMed ID: 23112293
PubMed ID: 23690988
Title: Specific distribution of the autophagic protein GABARAPL1/GEC1 in the developing and adult mouse brain and identification of neuronal populations expressing GABARAPL1/GEC1.
PubMed ID: 23690988
PubMed ID: 25127057
Title: TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.
PubMed ID: 25127057
PubMed ID: 24668264
Title: Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures.
PubMed ID: 24668264
PubMed ID: 26347139
Title: TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity.
PubMed ID: 26347139
PubMed ID: 26355087
Title: Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 1 Interacts with a Member of the Interferon-Stimulated Gene 15 Pathway.
PubMed ID: 26355087
DOI: 10.1128/jvi.01482-15
PubMed ID: 25684205
Title: CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.
PubMed ID: 25684205
PubMed ID: 26929408
Title: Structural and functional analysis of a novel interaction motif within UFM1-activating enzyme 5 (UBA5) required for binding to ubiquitin-like proteins and ufmylation.
PubMed ID: 26929408
PubMed ID: 29458288
Title: Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases.
PubMed ID: 29458288
PubMed ID: 29420192
Title: Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.
PubMed ID: 29420192
PubMed ID: 30661429
Title: Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells.
PubMed ID: 30661429
PubMed ID: 31006538
Title: Intrinsically disordered protein TEX264 mediates ER-phagy.
PubMed ID: 31006538
PubMed ID: 31006537
Title: TEX264 is an endoplasmic reticulum-resident ATG8-interacting protein critical for ER remodeling during nutrient stress.
PubMed ID: 31006537
PubMed ID: 31722778
Title: LIR motifs and the membrane-targeting domain are complementary in the function of RavZ.
PubMed ID: 31722778
PubMed ID: 32315611
Title: A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.
PubMed ID: 32315611
PubMed ID: 34338405
Title: Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control.
PubMed ID: 34338405
PubMed ID: 33909989
Title: Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine.
PubMed ID: 33909989
PubMed ID: 28287329
Title: ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
PubMed ID: 28287329
Sequence Information:
- Length: 117
- Mass: 14044
- Checksum: 7F56E345255F564B
- Sequence:
MKFQYKEDHP FEYRKKEGEK IRKKYPDRVP VIVEKAPKAR VPDLDKRKYL VPSDLTVGQF YFLIRKRIHL RPEDALFFFV NNTIPPTSAT MGQLYEDNHE EDYFLYVAYS DESVYGK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.