Details for: SHPK
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 3.05
Marker Score: 6,317 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.79
Marker Score: 625 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.04
Marker Score: 1,973 - Cell Name: thymocyte (CL0000893)
Fold Change: 1.04
Marker Score: 1,084 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.03
Marker Score: 16,103 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,407 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.96
Marker Score: 496 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.95
Marker Score: 449 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,411 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.95
Marker Score: 20,180 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.94
Marker Score: 2,220 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5,307 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,733 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.9
Marker Score: 1,830 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.87
Marker Score: 314 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,278 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.86
Marker Score: 360 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,269 - Cell Name: brush cell (CL0002204)
Fold Change: 0.75
Marker Score: 686 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.74
Marker Score: 661 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.71
Marker Score: 6,723 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.69
Marker Score: 5,906 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.68
Marker Score: 522 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.68
Marker Score: 186 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.68
Marker Score: 273 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.67
Marker Score: 216 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.67
Marker Score: 2,809 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.66
Marker Score: 170 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.64
Marker Score: 2,675 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.64
Marker Score: 6,013 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.63
Marker Score: 979 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.62
Marker Score: 2,396 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.61
Marker Score: 37,242 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.59
Marker Score: 21,658 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.58
Marker Score: 183 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.56
Marker Score: 334 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 443 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.52
Marker Score: 4,019 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 0.52
Marker Score: 1,478 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.52
Marker Score: 165 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.52
Marker Score: 7,752 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.52
Marker Score: 19,595 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.51
Marker Score: 386 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.5
Marker Score: 344 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.5
Marker Score: 238 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.49
Marker Score: 326 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.49
Marker Score: 9,721 - Cell Name: interneuron (CL0000099)
Fold Change: 0.46
Marker Score: 212 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.41
Marker Score: 182 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.4
Marker Score: 1,672 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.4
Marker Score: 117 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.37
Marker Score: 144 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.37
Marker Score: 205 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.36
Marker Score: 354 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.35
Marker Score: 1,359 - Cell Name: goblet cell (CL0000160)
Fold Change: 0.33
Marker Score: 2,212 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.33
Marker Score: 136 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.32
Marker Score: 338 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 0.32
Marker Score: 84 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.32
Marker Score: 341 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.3
Marker Score: 77 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.3
Marker Score: 319 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 0.29
Marker Score: 168 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.29
Marker Score: 221 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.28
Marker Score: 149 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.28
Marker Score: 277 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.27
Marker Score: 312 - Cell Name: enteric neuron (CL0007011)
Fold Change: 0.27
Marker Score: 143 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.27
Marker Score: 63 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 0.27
Marker Score: 323 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.26
Marker Score: 439 - Cell Name: precursor cell (CL0011115)
Fold Change: 0.25
Marker Score: 61 - Cell Name: enterocyte (CL0000584)
Fold Change: 0.25
Marker Score: 1,193 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.25
Marker Score: 85 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.24
Marker Score: 138 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.24
Marker Score: 161 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.24
Marker Score: 561 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.24
Marker Score: 130 - Cell Name: adventitial cell (CL0002503)
Fold Change: 0.23
Marker Score: 58 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.23
Marker Score: 476 - Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
Fold Change: 0.23
Marker Score: 175 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 0.22
Marker Score: 108 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.22
Marker Score: 233 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.22
Marker Score: 58 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.21
Marker Score: 61 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.21
Marker Score: 218 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.21
Marker Score: 70 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.21
Marker Score: 318 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.21
Marker Score: 140 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.2
Marker Score: 189 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.2
Marker Score: 218 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.2
Marker Score: 131 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.19
Marker Score: 685 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.19
Marker Score: 61 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 0.19
Marker Score: 293 - Cell Name: plasmacytoid dendritic cell, human (CL0001058)
Fold Change: 0.19
Marker Score: 50 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.18
Marker Score: 1,557 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 0.18
Marker Score: 69 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.18
Marker Score: 172 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.18
Marker Score: 80
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2316469479
Symbol: SHPK_HUMAN
Name: Carbohydrate kinase-like protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10673275
Title: The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion.
PubMed ID: 10673275
DOI: 10.1101/gr.10.2.165
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18186520
Title: Sedoheptulokinase deficiency due to a 57-kb deletion in cystinosis patients causes urinary accumulation of sedoheptulose: elucidation of the CARKL gene.
PubMed ID: 18186520
DOI: 10.1002/humu.20685
PubMed ID: 22682222
Title: The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism.
PubMed ID: 22682222
PubMed ID: 25647543
Title: First two unrelated cases of isolated sedoheptulokinase deficiency: A benign disorder?
PubMed ID: 25647543
Sequence Information:
- Length: 478
- Mass: 51505
- Checksum: 0C930B380826AC1E
- Sequence:
MAARPITLGI DLGTTSVKAA LLRAAPDDPS GFAVLASCAR AARAEAAVES AVAGPQGREQ DVSRILQALH ECLAALPRPQ LRSVVGIGVS GQMHGVVFWK TGQGCEWTEG GITPVFEPRA VSHLVTWQDG RCSSEFLASL PQPKSHLSVA TGFGCATIFW LLKYRPEFLK SYDAAGTIHD YVVAMLCGLP RPLMSDQNAA SWGYFNTQSQ SWNVETLRSS GFPVHLLPDI AEPGSVAGRT SHMWFEIPKG TQVGVALGDL QASVYSCMAQ RTDAVLNIST SVQLAASMPS GFQPAQTPDP TAPVAYFPYF NRTYLGVAAS LNGGNVLATF VHMLVQWMAD LGLEVEESTV YSRMIQAAVQ QRDTHLTITP TVLGERHLPD QLASVTRISS SDLSLGHVTR ALCRGIVQNL HSMLPIQQLQ EWGVERVMGS GSALSRNDVL KQEVQRAFPL PMSFGQDVDA AVGAALVMLR RHLNQKES
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.