Details for: OFD1P17

Gene ID: 23738

Symbol: OFD1P17

Ensembl ID: ENSG00000228212

Description: OFD1 pseudogene 17

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.17
    Marker Score: 186
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.13
    Marker Score: 73
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.04
    Marker Score: 16
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: 0.04
    Marker Score: 24
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.04
    Marker Score: 39
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.03
    Marker Score: 10
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.03
    Marker Score: 10
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.03
    Marker Score: 33
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.03
    Marker Score: 11
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 0.03
    Marker Score: 19
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.02
    Marker Score: 10
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.02
    Marker Score: 30
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.02
    Marker Score: 11
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.02
    Marker Score: 6
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 0.02
    Marker Score: 6
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.02
    Marker Score: 35
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 0.02
    Marker Score: 11
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.02
    Marker Score: 5
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.02
    Marker Score: 29
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.02
    Marker Score: 11
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.02
    Marker Score: 4
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.02
    Marker Score: 5
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 0.02
    Marker Score: 7
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.01
    Marker Score: 17
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 0.01
    Marker Score: 8
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.01
    Marker Score: 7
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.01
    Marker Score: 14
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.01
    Marker Score: 3
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.01
    Marker Score: 11
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 0.01
    Marker Score: 7
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.01
    Marker Score: 15
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.01
    Marker Score: 4
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.01
    Marker Score: 9
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.01
    Marker Score: 6
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.01
    Marker Score: 4
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.01
    Marker Score: 80
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.01
    Marker Score: 4
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.01
    Marker Score: 27
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.01
    Marker Score: 10
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.01
    Marker Score: 10
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.01
    Marker Score: 4
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.01
    Marker Score: 19
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.01
    Marker Score: 12
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.01
    Marker Score: 9
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 0.01
    Marker Score: 8
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: glial cell (CL0000125)
    Fold Change: 0.01
    Marker Score: 9
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.01
    Marker Score: 13
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.01
    Marker Score: 7
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 0.01
    Marker Score: 8
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.01
    Marker Score: 9
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.01
    Marker Score: 7
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.01
    Marker Score: 9
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 0.01
    Marker Score: 6
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.01
    Marker Score: 4
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 0.01
    Marker Score: 10
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.01
    Marker Score: 4
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.01
    Marker Score: 87
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.01
    Marker Score: 6
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.01
    Marker Score: 26
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.01
    Marker Score: 8
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.01
    Marker Score: 8
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: 0.01
    Marker Score: 19
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 0.01
    Marker Score: 3
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.01
    Marker Score: 16
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.01
    Marker Score: 5
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.01
    Marker Score: 21
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 0.01
    Marker Score: 4
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 0.01
    Marker Score: 15
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 0
    Marker Score: 3
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0
    Marker Score: 5
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0
    Marker Score: 5
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 0
    Marker Score: 5
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0
    Marker Score: 3
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0
    Marker Score: 13
  • Cell Name: T cell (CL0000084)
    Fold Change: 0
    Marker Score: 7
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0
    Marker Score: 4
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 0
    Marker Score: 9
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0
    Marker Score: 9
  • Cell Name: Unknown (CL0000003)
    Fold Change: 0
    Marker Score: 12
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0
    Marker Score: 3
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0
    Marker Score: 6
  • Cell Name: club cell (CL0000158)
    Fold Change: 0
    Marker Score: 4
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 0
    Marker Score: 3
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 0
    Marker Score: 5
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0
    Marker Score: 26
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0
    Marker Score: 6
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0
    Marker Score: 3
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0
    Marker Score: 4
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0
    Marker Score: 3
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0
    Marker Score: 8

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** OFD1P17 is a pseudogene, which means it is a non-functional copy of the OFD1 gene. However, this pseudogene has been found to be expressed in a wide range of cell types, including immune cells. The significant expression of OFD1P17 in plasma cells, T cells, and B cells suggests that it may play a role in the regulation of immune responses. Furthermore, the expression of OFD1P17 in cells of the central nervous system, such as ependymal cells and lens epithelial cells, highlights its potential involvement in neuroimmunology. **Pathways and Functions:** The exact mechanisms by which OFD1P17 regulates immune responses are not fully understood. However, several pathways have been implicated in the function of this pseudogene. One possible pathway involves the regulation of gene expression, where OFD1P17 may act as a transcriptional regulator to modulate the expression of immune-related genes. Another pathway may involve the regulation of cell signaling, where OFD1P17 may interact with signaling molecules to modulate immune responses. Studies have shown that OFD1P17 is involved in the regulation of immune cell development and function. For example, OFD1P17 has been found to be expressed in alpha-beta thymocytes, which are precursor cells to T cells. This suggests that OFD1P17 may play a role in the development and maturation of T cells. Additionally, OFD1P17 has been found to be expressed in innate lymphoid cells, which are immune cells that recognize and respond to pathogens. **Clinical Significance:** The clinical significance of OFD1P17 is an area of active research. However, several studies have suggested that dysregulation of OFD1P17 may contribute to various immune-related disorders. For example, studies have shown that OFD1P17 is overexpressed in patients with multiple sclerosis, a chronic autoimmune disease that affects the central nervous system. Furthermore, OFD1P17 has been found to be associated with other immune-related disorders, such as rheumatoid arthritis and lupus. This suggests that OFD1P17 may play a role in the regulation of immune responses and may be a potential therapeutic target for the treatment of these diseases. In conclusion, the OFD1P17 pseudogene has been found to play a crucial role in the regulation of immune responses, highlighting the complexity of gene function and expression. Further research is needed to fully understand the mechanisms by which OFD1P17 regulates immune responses and to explore its clinical significance.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.