Details for: SDF2L1
Gene ID: 23753
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: SDF2L1
Ensembl ID: ENSG00000128228
Description: stromal cell derived factor 2 like 1
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 83.11rCSI 65.38%PRS 62.11
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CSI 61.76rCSI 63.22%PRS 71.6
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CSI 53.15rCSI 46.02%PRS 60.07
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CSI 52.15rCSI 68.35%PRS 83.99
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CSI 42.84rCSI 44.88%PRS 58.63
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CSI 42.08rCSI 34.03%PRS 56.61
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CSI 41.93rCSI 50.22%PRS 73.28
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CSI 41.21rCSI 59.44%PRS 65.15
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CSI 38.83rCSI 34.47%PRS 53.59
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CSI 36.12rCSI 44.68%PRS 51.33
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CSI 24.42rCSI 23.54%PRS 45.83
-
CSI 24.06rCSI 23.66%PRS 57.78
-
CSI 23.22rCSI 13.71%PRS 72.26
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CSI 21.16rCSI 30.96%PRS 59.28
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CSI 20.74rCSI 36.57%PRS 63.7
-
CSI 20.26rCSI 19.14%PRS 55.22
-
CSI 20.24rCSI 18.67%PRS 56.51
-
CSI 16.62rCSI 28.48%PRS 64.74
-
CSI 16.12rCSI 14.9%PRS 75.35
-
CSI 15.46rCSI 69.56%PRS 88.09
-
CSI 15.4rCSI 32.78%PRS 67.92
-
CSI 15.31rCSI 23.41%PRS 70.1
-
CSI 14.61rCSI 13.59%PRS 55.26
-
CSI 14.59rCSI 47.32%PRS 56.83
-
CSI 13.92rCSI 30.48%PRS 64.02
-
CSI 13.53rCSI 20.91%PRS 53.41
-
CSI 13.2rCSI 25.67%PRS 57.87
-
CSI 13.11rCSI 17.43%PRS 60.96
-
CSI 12.93rCSI 8.62%PRS 77.24
-
CSI 12.48rCSI 18.43%PRS 71.85
-
CSI 11.69rCSI 16.85%PRS 66.95
-
CSI 11.51rCSI 8%PRS 65.79
-
CSI 11.29rCSI 11.83%PRS 52.13
-
CSI 11.15rCSI 24.68%PRS 53.17
-
CSI 10.3rCSI 9.38%PRS 69.72
-
CSI 10.21rCSI 29.29%PRS 74.86
-
CSI 9.92rCSI 21.85%PRS 59.26
-
CSI 9.9rCSI 16.05%PRS 52.63
-
CSI 9.54rCSI 12.24%PRS 60.28
-
CSI 9.54rCSI 12.24%PRS 52.86
-
CSI 9.42rCSI 43.22%PRS 68.98
-
CSI 9.33rCSI 17.61%PRS 65.88
-
CSI 9.15rCSI 12.67%PRS 57.75
-
CSI 9.15rCSI 36.56%PRS 73.24
-
CSI 8.73rCSI 37.89%PRS 69.46
-
CSI 8.73rCSI 50.79%PRS 65.19
-
CSI 8.68rCSI 20.64%PRS 65.64
-
CSI 8.48rCSI 5.92%PRS 58.05
-
CSI 8.46rCSI 7.44%PRS 43.62
-
CSI 8.26rCSI 14.78%PRS 54.22
-
CSI 8.25rCSI 11.77%PRS 57.83
-
CSI 8.25rCSI 36.67%PRS 89.61
-
CSI 8.18rCSI 12.68%PRS 63.32
-
CSI 8.08rCSI 13.31%PRS 60.6
-
CSI 7.56rCSI 7.89%PRS 55.8
-
CSI 7.32rCSI 13.97%PRS 71.08
-
CSI 7.3rCSI 5.93%PRS 55.72
-
CSI 7.19rCSI 6.6%PRS 63.75
-
CSI 7.1rCSI 18.03%PRS 50.07
-
CSI 7.08rCSI 12.1%PRS 79.99
-
CSI 6.97rCSI 12.67%PRS 71.36
-
CSI 6.65rCSI 12.8%PRS 82.6
-
CSI 6.63rCSI 10.69%PRS 60.57
-
CSI 6.56rCSI 17.26%PRS 75.34
-
CSI 6.52rCSI 28.19%PRS 69.2
-
CSI 6.5rCSI 22.8%PRS 68.98
-
CSI 6.48rCSI 5.37%PRS 54.22
-
CSI 6.41rCSI 5.37%PRS 60.09
-
CSI 6.27rCSI 4.17%PRS 58.85
-
CSI 6.12rCSI 13.99%PRS 54.86
-
CSI 6.05rCSI 4.53%PRS 70.62
-
CSI 5.98rCSI 6.73%PRS 71.97
-
CSI 5.97rCSI 15.76%PRS 63.91
-
CSI 5.85rCSI 4.53%PRS 56.65
-
CSI 5.74rCSI 5.65%PRS 78.76
-
CSI 5.7rCSI 7.8%PRS 60.93
-
CSI 5.67rCSI 19.16%PRS 61.28
-
CSI 5.62rCSI 8.63%PRS 53.12
-
CSI 5.6rCSI 6.5%PRS 63.99
-
CSI 5.54rCSI 4.16%PRS 60.16
-
CSI 5.45rCSI 4.09%PRS 83.8
-
CSI 5.34rCSI 4.27%PRS 76.39
-
CSI 5.3rCSI 7.24%PRS 57.5
-
CSI 5.23rCSI 7%PRS 56.13
-
CSI 5.2rCSI 9.92%PRS 76.35
-
CSI 5.06rCSI 10.49%PRS 52.57
-
CSI 5.01rCSI 49.3%PRS 76.75
-
CSI 4.94rCSI 6.01%PRS 63.13
-
CSI 4.9rCSI 4.89%PRS 48.89
-
CSI 4.86rCSI 7.42%PRS 71.86
-
CSI 4.82rCSI 26.25%PRS 73.54
-
CSI 4.68rCSI 3.54%PRS 68.9
-
CSI 4.64rCSI 21.41%PRS 75.24
-
CSI 4.63rCSI 4.46%PRS 55.74
-
CSI 4.61rCSI 6.04%PRS 68.88
-
CSI 4.58rCSI 7.31%PRS 48.31
-
CSI 4.53rCSI 49.31%PRS 72.07
-
CSI 4.53rCSI 6.64%PRS 52.49
-
CSI 4.45rCSI 5.23%PRS 58.33
-
CSI 4.45rCSI 3.19%PRS 69.49
-
CSI 0.2rCSI 1.2%PRS 48.4%
-
CSI 0.2rCSI 1.6%PRS 75.8%
-
CSI 0.2rCSI 1.3%PRS 65.8%
-
CSI 0.3rCSI 4.8%PRS 75.6%
-
CSI 0.3rCSI 3.3%PRS 75.4%
-
CSI 0.4rCSI 2.6%PRS 76.1%
-
CSI 0.5rCSI 11.0%PRS 76.2%
-
CSI 0.6rCSI 3.2%PRS 68.9%
-
CSI 0.6rCSI 1.8%PRS 68.5%
-
CSI 0.6rCSI 1.9%PRS 74.7%
-
CSI 0.6rCSI 2.8%PRS 54.5%
-
CSI 0.7rCSI 3.5%PRS 87.8%
-
CSI 0.7rCSI 2.1%PRS 61.4%
-
CSI 0.7rCSI 1.7%PRS 45.0%
-
CSI 0.7rCSI 3.4%PRS 66.8%
-
CSI 0.8rCSI 3.6%PRS 85.0%
-
CSI 0.8rCSI 1.7%PRS 74.1%
-
CSI 0.9rCSI 1.1%PRS 57.3%
-
CSI 0.9rCSI 4.2%PRS 74.3%
-
CSI 0.9rCSI 3.3%PRS 75.2%
-
CSI 0.9rCSI 23.1%PRS 75.7%
-
CSI 1.0rCSI 1.1%PRS 76.0%
-
CSI 1.0rCSI 2.8%PRS 63.1%
-
CSI 1.0rCSI 1.6%PRS 59.9%
-
CSI 1.1rCSI 3.3%PRS 65.4%
-
CSI 1.1rCSI 0.8%PRS 73.0%
-
CSI 1.1rCSI 1.4%PRS 77.6%
-
CSI 1.1rCSI 1.6%PRS 58.6%
-
CSI 1.1rCSI 8.6%PRS 73.0%
-
CSI 1.2rCSI 4.6%PRS 71.0%
-
CSI 1.3rCSI 29.0%PRS 94.5%
-
CSI 1.3rCSI 3.1%PRS 53.3%
-
CSI 1.3rCSI 3.4%PRS 60.8%
-
CSI 1.3rCSI 2.2%PRS 45.3%
-
CSI 1.4rCSI 2.4%PRS 78.9%
-
CSI 1.4rCSI 9.5%PRS 70.1%
-
CSI 1.4rCSI 2.2%PRS 56.0%
-
CSI 1.4rCSI 3.1%PRS 71.3%
-
CSI 1.7rCSI 4.3%PRS 82.2%
-
CSI 1.7rCSI 4.8%PRS 68.0%
-
CSI 1.8rCSI 2.5%PRS 60.3%
-
CSI 1.8rCSI 2.1%PRS 45.2%
-
CSI 1.9rCSI 2.5%PRS 47.7%
-
CSI 1.9rCSI 3.6%PRS 75.2%
-
CSI 1.9rCSI 10.9%PRS 65.5%
-
CSI 1.9rCSI 5.2%PRS 86.4%
-
CSI 1.9rCSI 2.1%PRS 54.1%
-
CSI 2.0rCSI 4.5%PRS 76.1%
-
CSI 2.0rCSI 3.0%PRS 80.6%
-
CSI 2.0rCSI 12.6%PRS 74.8%
-
CSI 2.0rCSI 5.7%PRS 69.6%
-
CSI 2.0rCSI 1.5%PRS 69.2%
-
CSI 2.0rCSI 3.5%PRS 45.5%
-
CSI 2.1rCSI 2.0%PRS 78.4%
-
CSI 2.1rCSI 7.8%PRS 47.6%
-
CSI 2.2rCSI 2.6%PRS 75.4%
-
CSI 2.2rCSI 2.7%PRS 53.6%
-
CSI 2.2rCSI 2.9%PRS 61.7%
-
CSI 2.3rCSI 2.3%PRS 68.8%
-
CSI 2.3rCSI 2.0%PRS 66.0%
-
CSI 2.4rCSI 1.6%PRS 67.9%
-
CSI 2.5rCSI 2.2%PRS 60.6%
-
CSI 2.5rCSI 2.0%PRS 73.2%
-
CSI 2.5rCSI 1.9%PRS 55.1%
-
CSI 2.5rCSI 12.8%PRS 83.0%
-
CSI 2.5rCSI 5.0%PRS 75.0%
-
CSI 2.6rCSI 5.9%PRS 52.5%
-
CSI 2.7rCSI 4.2%PRS 59.3%
-
CSI 2.7rCSI 14.5%PRS 68.8%
-
CSI 2.7rCSI 6.0%PRS 68.7%
-
CSI 2.7rCSI 10.6%PRS 61.9%
-
CSI 2.8rCSI 3.3%PRS 45.2%
-
CSI 2.8rCSI 4.1%PRS 66.9%
-
CSI 2.8rCSI 5.0%PRS 69.7%
-
CSI 2.8rCSI 12.2%PRS 46.9%
-
CSI 2.8rCSI 10.0%PRS 86.8%
-
CSI 2.9rCSI 3.1%PRS 67.3%
-
CSI 2.9rCSI 3.1%PRS 53.8%
-
CSI 3.0rCSI 4.3%PRS 71.4%
-
CSI 3.0rCSI 2.4%PRS 77.4%
-
CSI 3.1rCSI 4.2%PRS 80.9%
-
CSI 3.1rCSI 4.9%PRS 56.9%
-
CSI 3.2rCSI 6.0%PRS 85.8%
-
CSI 3.2rCSI 4.5%PRS 54.3%
-
CSI 3.2rCSI 4.8%PRS 60.7%
-
CSI 3.3rCSI 6.2%PRS 72.4%
-
CSI 3.3rCSI 43.6%PRS 84.2%
-
CSI 3.3rCSI 4.1%PRS 66.1%
-
CSI 3.4rCSI 5.2%PRS 63.9%
-
CSI 3.4rCSI 4.5%PRS 64.4%
-
CSI 3.4rCSI 2.9%PRS 61.8%
-
CSI 3.5rCSI 3.1%PRS 52.2%
-
CSI 3.5rCSI 4.3%PRS 65.7%
-
CSI 3.5rCSI 4.4%PRS 68.0%
-
CSI 3.6rCSI 12.9%PRS 65.7%
-
CSI 3.7rCSI 8.2%PRS 62.9%
-
CSI 3.7rCSI 3.6%PRS 71.2%
-
CSI 3.7rCSI 10.7%PRS 57.1%
-
CSI 3.8rCSI 10.8%PRS 70.5%
-
CSI 3.8rCSI 3.9%PRS 61.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 669395550
Symbol: SDF2L_HUMAN
Name: Stromal cell-derived factor 2-like protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11162531
Title: Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family.
PubMed ID: 11162531
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 15461802
Title: A genome annotation-driven approach to cloning the human ORFeome.
PubMed ID: 15461802
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12475965
Title: A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.
PubMed ID: 12475965
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 221
- Mass: 23598
- Checksum: D6F15E1EB48428EE
- Sequence:
MWSAGRGGAA WPVLLGLLLA LLVPGGGAAK TGAELVTCGS VLKLLNTHHR VRLHSHDIKY GSGSGQQSVT GVEASDDANS YWRIRGGSEG GCPRGSPVRC GQAVRLTHVL TGKNLHTHHF PSPLSNNQEV SAFGEDGEGD DLDLWTVRCS GQHWEREAAV RFQHVGTSVF LSVTGEQYGS PIRGQHEVHG MPSANTHNTW KAMEGIFIKP SVEPSAGHDE L