Details for: BRD1

Gene ID: 23774

Symbol: BRD1

Ensembl ID: ENSG00000100425

Description: bromodomain containing 1

Associated with

Other Information

Genular Protein ID: 217727921

Symbol: BRD1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10602503

Title: The cloning, mapping and expression of a novel gene, BRL, related to the AF10 leukaemia gene.

PubMed ID: 10602503

DOI: 10.1038/sj.onc.1203117

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16387653

Title: ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

PubMed ID: 16387653

DOI: 10.1016/j.molcel.2005.12.007

PubMed ID: 18794358

Title: Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

PubMed ID: 18794358

DOI: 10.1128/mcb.01297-08

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21753189

Title: The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.

PubMed ID: 21753189

DOI: 10.1182/blood-2011-01-331892

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 21880731

Title: Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF).

PubMed ID: 21880731

DOI: 10.1074/jbc.m111.244400

PubMed ID: 21720545

Title: Structural and histone binding ability characterizations of human PWWP domains.

PubMed ID: 21720545

DOI: 10.1371/journal.pone.0018919

PubMed ID: 22464331

Title: Histone recognition and large-scale structural analysis of the human bromodomain family.

PubMed ID: 22464331

DOI: 10.1016/j.cell.2012.02.013

PubMed ID: 28334966

Title: Structural and mechanistic insights into regulation of HBO1 histone acetyltransferase activity by BRPF2.

PubMed ID: 28334966

DOI: 10.1093/nar/gkx142

PubMed ID: 31827282

Title: HBO1 is required for the maintenance of leukaemia stem cells.

PubMed ID: 31827282

DOI: 10.1038/s41586-019-1835-6

PubMed ID: 28584052

Title: Mutations in N-acetylglucosamine (O-GlcNAc) transferase in patients with X-linked intellectual disability.

PubMed ID: 28584052

DOI: 10.1074/jbc.m117.790097

Sequence Information:

  • Length: 1058
  • Mass: 119520
  • Checksum: 6E7B07E8A030E104
  • Sequence:
  • MRRKGRCHRG SAARHPSSPC SVKHSPTRET LTYAQAQRMV EIEIEGRLHR ISIFDPLEII 
    LEDDLTAQEM SECNSNKENS ERPPVCLRTK RHKNNRVKKK NEALPSAHGT PASASALPEP 
    KVRIVEYSPP SAPRRPPVYY KFIEKSAEEL DNEVEYDMDE EDYAWLEIVN EKRKGDCVPA 
    VSQSMFEFLM DRFEKESHCE NQKQGEQQSL IDEDAVCCIC MDGECQNSNV ILFCDMCNLA 
    VHQECYGVPY IPEGQWLCRH CLQSRARPAD CVLCPNKGGA FKKTDDDRWG HVVCALWIPE 
    VGFANTVFIE PIDGVRNIPP ARWKLTCYLC KQKGVGACIQ CHKANCYTAF HVTCAQKAGL 
    YMKMEPVKEL TGGGTTFSVR KTAYCDVHTP PGCTRRPLNI YGDVEMKNGV CRKESSVKTV 
    RSTSKVRKKA KKAKKALAEP CAVLPTVCAP YIPPQRLNRI ANQVAIQRKK QFVERAHSYW 
    LLKRLSRNGA PLLRRLQSSL QSQRSSQQRE NDEEMKAAKE KLKYWQRLRH DLERARLLIE 
    LLRKREKLKR EQVKVEQVAM ELRLTPLTVL LRSVLDQLQD KDPARIFAQP VSLKEVPDYL 
    DHIKHPMDFA TMRKRLEAQG YKNLHEFEED FDLIIDNCMK YNARDTVFYR AAVRLRDQGG 
    VVLRQARREV DSIGLEEASG MHLPERPAAA PRRPFSWEDV DRLLDPANRA HLGLEEQLRE 
    LLDMLDLTCA MKSSGSRSKR AKLLKKEIAL LRNKLSQQHS QPLPTGPGLE GFEEDGAALG 
    PEAGEEVLPR LETLLQPRKR SRSTCGDSEV EEESPGKRLD AGLTNGFGGA RSEQEPGGGL 
    GRKATPRRRC ASESSISSSN SPLCDSSFNA PKCGRGKPAL VRRHTLEDRS ELISCIENGN 
    YAKAARIAAE VGQSSMWIST DAAASVLEPL KVVWAKCSGY PSYPALIIDP KMPRVPGHHN 
    GVTIPAPPLD VLKIGEHMQT KSDEKLFLVL FFDNKRSWQW LPKSKMVPLG IDETIDKLKM 
    MEGRNSSIRK AVRIAFDRAM NHLSRVHGEP TSDLSDID

Genular Protein ID: 1211512242

Symbol: Q59G93_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 471
  • Mass: 53880
  • Checksum: 5B9B516F3CED41C9
  • Sequence:
  • KMASVEKRAR LKRSGPHPRS GRRQKKAKKA LAEPCAVLPT VCAPYIPPQR LNRIANQVAI 
    QRKKQFVERA HSYWLLKRLS RNGAPLLRRL QSSLQSQRSS QQRENDEEMK AAKEKLKYWQ 
    RLRHDLERAR LLIELLRKRE KLKREQVKVE QVAMELRLTP LTVLLRSVLD QLQDKDPARI 
    FAQPVSLKEV PDYLDHIKHP MDFATMRKRL EAQGYKNLHE FEEDFDLIID NCMKYNARDT 
    VFYRAAVRLR DQGGVVLRQA RREVDSIGLE EASGMHLPER PAAAPRRPFS WEDVDRLLDP 
    ANRAHLGLEE QLRELLDMLD LTCAMKSSGS RSKRAKLLKK EIALLRNKLS QQHSQPLPTG 
    PGLEGFEEDG AALGPEAGEE ARDQNLFVCS PSEVGDSSAA KEKVAEHMRR LRGGGGVPRK 
    APGRRSHQRL WGCEERAGAG RRPGEEGHTP TTLCLRVQHL LQQQPALRLE L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.