Genular: Defining Cellular Identity and Function

Details for: Capn10

Gene ID: 23830

Symbol: Capn10

Ensembl ID: ENSMUSG00000026270

Description: calpain 10

Associated with

Degradation of the extracellular matrix
(R-MMU-1474228)
Extracellular matrix organization
(R-MMU-1474244)
Calcium-dependent cysteine-type endopeptidase activity
(GO:0004198)
Cellular response to insulin stimulus
(GO:0032869)
Cysteine-type peptidase activity
(GO:0008234)
Cytoplasm
(GO:0005737)
Cytoskeletal protein binding
(GO:0008092)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Hydrolase activity
(GO:0016787)
Membrane
(GO:0016020)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial matrix
(GO:0005759)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Mitochondrion organization
(GO:0007005)
Peptidase activity
(GO:0008233)
Plasma membrane
(GO:0005886)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of insulin secretion
(GO:0032024)
Positive regulation of intracellular transport
(GO:0032388)
Positive regulation of type b pancreatic cell apoptotic process
(GO:2000676)
Protein catabolic process
(GO:0030163)
Proteolysis
(GO:0006508)
Regulation of actin cytoskeleton organization
(GO:0032956)
Response to nutrient levels
(GO:0031667)
Snare binding
(GO:0000149)
Type b pancreatic cell apoptotic process
(GO:0097050)

Other Information

Proteins

Calpain-10

Genular Protein ID: 2165933585

Symbol: CAN10_MOUSE

Name: Calpain-10

UniProtKB Accession Codes:

Q9ESK3 Q99J13 Q9WVF0

Database IDs:

Citations:

PubMed ID: 11017071

Title: Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.

PubMed ID: 11017071

DOI: 10.1038/79876

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 666
Mass: 74596
Checksum: A0B1B37EE1DE2371
Sequence:

MRAVRAETPA RELFRDAAFP ASDSSLFYNL STPLAQFRED ITWRRPQEIC ATPQLFPDNP 
WEGQVKQGLL GDCWFLCACA ALQKSQHLLD QVFPPGQPGW SDQKYQGFFT CRIWQFGHWE 
EVTIDDRLPC LAGRLCFSRC QREDVFWLPL LEKAYAKVHG SYEHLWAGQV ADALVDLTGS 
LAERWSLKDV TKASGQQDRP SGGEHRTCRQ LLHLKDRCLI SCSVLSPRAG ARELGEFHAF 
IISDLQELRS QTGQGILLLR IHNPWGRRCW QGLWREGGEG WNQVEPAKES ELLAQLQEGE 
FWVEEEEFLR EFDEVTIGYP VTEAGHLQSL HTERVLCHTR TLPGAWVTGQ SAGGCRNNSC 
FPCNPKFWLR LLEPSEVCVA VLQRPRRRLV GQTRALAGAS PAPVNLPGKD YQAVGLHIWK 
VEKRKISLPR VLSAPPVAGT ACHAYDREIH LRCELSPGYY LAVPSTFLKD VPGQFLLRVF 
STGKISLSAV RLATKGASPG TALPAGEWET VQLQGCWRAG QTAGGSRNFA SYPCNPCLPF 
SVPEGAGPRY IRITLQQHCR LSDSQLHPIG FHVFQVPADG ENQDACSLLL QEPLLSCVPH 
RYAQEVSRLC LLSVGNYRIV PSTYLPDTEG TFTVTIATRI DRQSIHSQEM LGQLLQEVSF 
MAVMKA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.