Details for: Clca1

Gene ID: 23844

Symbol: Clca1

Ensembl ID: ENSMUSG00000028255

Description: chloride channel accessory 1

Associated with

Other Information

Genular Protein ID: 3009722575

Symbol: CLCA1_MOUSE

Name: Calcium-activated chloride channel regulator 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10049711

Title: Cloning and identification of the gene gob-5, which is expressed in intestinal goblet cells in mice.

PubMed ID: 10049711

DOI: 10.1006/bbrc.1999.0168

PubMed ID: 11694454

Title: Characterization of a calcium-activated chloride channel as a shared target of Th2 cytokine pathways and its potential involvement in asthma.

PubMed ID: 11694454

DOI: 10.1165/ajrcmb.25.4.4578

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11296262

Title: Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma.

PubMed ID: 11296262

DOI: 10.1073/pnas.081510898

PubMed ID: 12019299

Title: The murine mCLCA3 (alias gob-5) protein is located in the mucin granule membranes of intestinal, respiratory, and uterine goblet cells.

PubMed ID: 12019299

DOI: 10.1177/002215540205000609

PubMed ID: 16251409

Title: Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis.

PubMed ID: 16251409

DOI: 10.1016/s0002-9440(10)61212-6

PubMed ID: 15919655

Title: hCLCA1 and mCLCA3 are secreted non-integral membrane proteins and therefore are not ion channels.

PubMed ID: 15919655

DOI: 10.1074/jbc.m504654200

PubMed ID: 16099848

Title: Blue native/SDS-PAGE analysis reveals reduced expression of the mClCA3 protein in cystic fibrosis knock-out mice.

PubMed ID: 16099848

DOI: 10.1074/mcp.m500098-mcp200

PubMed ID: 16645179

Title: Gob-5 contributes to goblet cell hyperplasia and modulates pulmonary tissue inflammation.

PubMed ID: 16645179

DOI: 10.1165/rcmb.2005-0451oc

PubMed ID: 16895902

Title: Both cleavage products of the mCLCA3 protein are secreted soluble proteins.

PubMed ID: 16895902

DOI: 10.1074/jbc.m606489200

Sequence Information:

  • Length: 913
  • Mass: 100071
  • Checksum: A7FA2F9E1089806D
  • Sequence:
  • MESLKSPVFL LILHLLEGVL SESLIQLNNN GYEGIVIAID HDVPEDEALI QHIKDMVTQA 
    SPYLFEATGK RFYFKNVAIL IPESWKAKPE YTRPKLETFK NADVLVSTTS PLGNDEPYTE 
    HIGACGEKGI RIHLTPDFLA GKKLTQYGPQ DRTFVHEWAH FRWGVFNEYN NDEKFYLSKG 
    KPQAVRCSAA ITGKNQVRRC QGGSCITNGK CVIDRVTGLY KDNCVFVPDP HQNEKASIMF 
    NQNINSVVEF CTEKNHNQEA PNDQNQRCNL RSTWEVIQES EDFKQTTPMT AQPPAPTFSL 
    LQIGQRIVCL VLDKSGSMLN DDRLNRMNQA SRLFLLQTVE QGSWVGMVTF DSAAYVQSEL 
    KQLNSGADRD LLIKHLPTVS AGGTSICSGL RTAFTVIKKK YPTDGSEIVL LTDGEDNTIS 
    SCFDLVKQSG AIIHTVALGP AAAKELEQLS KMTGGLQTYS SDQVQNNGLV DAFAALSSGN 
    AAIAQHSIQL ESRGVNLQNN QWMNGSVIVD SSVGKDTLFL ITWTTHPPTI FIWDPSGVEQ 
    NGFILDTTTK VAYLQVPGTA KVGFWKYSIQ ASSQTLTLTV TSRAASATLP PITVTPVVNK 
    NTGKFPSPVT VYASIRQGAS PILRASVTAL IESVNGKTVT LELLDNGAGA DATKNDGVYS 
    RFFTAFDANG RYSVKIWALG GVTSDRQRAA PPKNRAMYID GWIEDGEVRM NPPRPETSYV 
    QDKQLCFSRT SSGGSFVATN VPAAAPIPDL FPPCQITDLK ASIQGQNLVN LTWTAPGDDY 
    DHGRASNYII RMSTSIVDLR DHFNTSLQVN TTGLIPKEAS SEEIFEFELG GNTFGNGTDI 
    FIAIQAVDKS NLKSEISNIA RVSVFIPAQE PPIPEDSTPP CPDISINSTI PGIHVLKIMW 
    KWLGEMQVTL GLH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.