Genular: Defining Cellular Identity and Function

Details for: Clec5a

Gene ID: 23845

Symbol: Clec5a

Ensembl ID: ENSMUSG00000029915

Description: C-type lectin domain family 5, member a

Associated with

Dap12 interactions
(R-MMU-2172127)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Carbohydrate binding
(GO:0030246)
Cell surface
(GO:0009986)
Cytosol
(GO:0005829)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Membrane
(GO:0016020)
Myeloid cell differentiation
(GO:0030099)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of myeloid cell apoptotic process
(GO:0033033)
Osteoblast development
(GO:0002076)
Plasma membrane
(GO:0005886)
Positive regulation of cytokine production
(GO:0001819)
Protein binding
(GO:0005515)
Virus receptor activity
(GO:0001618)

Other Information

Proteins

C-type lectin domain family 5 member A

Genular Protein ID: 1674269617

Symbol: CLC5A_MOUSE

Name: C-type lectin domain family 5 member A

UniProtKB Accession Codes:

Q9R007 Q3SXC9 Q3UV97 Q8BL24

Database IDs:

Citations:

PubMed ID: 10449773

Title: Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells.

PubMed ID: 10449773

DOI: 10.1073/pnas.96.17.9792

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19074552

Title: Expression and functional role of MDL-1 (CLEC5A) in mouse myeloid lineage cells.

PubMed ID: 19074552

DOI: 10.1189/jlb.0508329

PubMed ID: 19251634

Title: Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12.

PubMed ID: 19251634

DOI: 10.1073/pnas.0900463106

PubMed ID: 20212065

Title: Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis.

PubMed ID: 20212065

DOI: 10.1084/jem.20090516

PubMed ID: 20637688

Title: Expression profile of Japanese encephalitis virus induced neuroinflammation and its implication in disease severity.

PubMed ID: 20637688

DOI: 10.1016/j.jcv.2010.06.009

Sequence Information:

Length: 190
Mass: 21696
Checksum: AB6AACB3A8D36637
Sequence:

MNWHMIISGL IVVVIKVVGM TFFLLYFPQV FGKSNDGFVP TESYGTTSVQ NVSQIFGRND 
ESTMPTRSYG TVCPRNWDFH QGKCFFFSFS ESPWKDSMDY CATQGSTLAI VNTPEKLKYL 
QDIAGIENYF IGLVRQPGEK KWRWINNSVF NGNVTNQDQN FDCVTIGLTK TYDAASCEVS 
YRWICEMNAK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Clec5a

Associated with

Other Information

Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells. PubMed ID: 10449773

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Expression and functional role of MDL-1 (CLEC5A) in mouse myeloid lineage cells. PubMed ID: 19074552

Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12. PubMed ID: 19251634

Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis. PubMed ID: 20212065

Expression profile of Japanese encephalitis virus induced neuroinflammation and its implication in disease severity. PubMed ID: 20637688