Details for: Dmtf1

Gene ID: 23857

Symbol: Dmtf1

Ensembl ID: ENSMUSG00000042508

Description: cyclin D binding myb like transcription factor 1

Associated with

  • Cell cycle
    (GO:0007049)
  • Cytosol
    (GO:0005829)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Other Information

Genular Protein ID: 725322836

Symbol: DMTF1_MOUSE

Name: Cyclin-D-binding Myb-like transcription factor 1

UniProtKB Accession Codes:

Q8CE22 P70413 Q3TUR9 Q80VR8 Q8BQX6 Q8CA56 Q8CCZ0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 7 EPD 1 Ensembl 6 ExpressionAtlas 1 GO 9 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 RNAct 1 RefSeq 3 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 3 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8887674

Title: Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1.

PubMed ID: 8887674

DOI: 10.1128/mcb.16.11.6457

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9786929

Title: Regulation of the CD13/aminopeptidase N gene by DMP1, a transcription factor antagonized by D-type cyclins.

PubMed ID: 9786929

DOI: 10.1074/jbc.273.44.29188

PubMed ID: 9488476

Title: Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanism.

PubMed ID: 9488476

DOI: 10.1128/mcb.18.3.1590

PubMed ID: 10097151

Title: Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1.

PubMed ID: 10097151

DOI: 10.1073/pnas.96.7.3993

PubMed ID: 10898794

Title: Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis.

PubMed ID: 10898794

PubMed ID: 11711428

Title: Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas.

PubMed ID: 11711428

DOI: 10.1101/gad.929901

PubMed ID: 15601844

Title: Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor.

PubMed ID: 15601844

DOI: 10.1128/mcb.25.1.220-232.2005

PubMed ID: 16878159

Title: Expression of Dmp1 in specific differentiated, nonproliferating cells and its regulation by E2Fs.

PubMed ID: 16878159

DOI: 10.1038/sj.onc.1209750

PubMed ID: 17936562

Title: Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer.

PubMed ID: 17936562

DOI: 10.1016/j.ccr.2007.08.034

PubMed ID: 17546045

Title: Repression of Dmp1 and Arf transcription by anthracyclins: critical roles of the NF-kappaB subunit p65.

PubMed ID: 17546045

DOI: 10.1038/sj.onc.1210568

Sequence Information:

  • Length: 761
  • Mass: 84644
  • Checksum: DB93810B0991CBE3
  • Sequence:
    • MSTVEEDSDT VTVETVNSVT FTQDTDGNLI LHCPQNDPDE VDSEDSTEPP HKRLCLSSED 
DQSIDDATPC ISVVALPLSE NDQSFEVTMT ATTEVADDEL SEGTVTQIQI LQNDQLDEIS 
PLGTEEVSAV SQAWFTTKED KDSLTNKGHK WKQGMWSKEE IDILMNNIER YLKARGIKDA 
TEIIFEMSKD ERKDFYRTIA WGLNRPLFAV YRRVLRMYDD RNHVGKYTPE EIEKLKELRI 
KHGNDWATIG AALGRSASSV KDRCRLMKDT CNTGKWTEEE EKRLAEVVHE LTSTEPGDIV 
TQGVSWAAVA ERVGTRSEKQ CRSKWLNYLN WKQSGGTEWT KEDEINLILR IAELDVADEN 
DINWDLLAEG WSSVRSPQWL RSKWWTIKRQ IANHKDVSFP VLIKGLKQLH ENQKNNPVLL 
ENKSGSGVPN SNCNSSVQHV QIRVARLEDN TAISPSPMAA LQIPVQITHV SSTDSPAASV 
DSETITLNSG TLQTFEILPS FHLQPTGTPG TYLLQTSSSQ GLPLTLTTNP TVTLAAAAPA 
SPEQIIVHAL SPEHLLNTSD NVTVQCHTPR VIIQTVATED ITSSLSQEEL TVDSDLHSSD 
FPEPPDALEA DTFPDEIPRP KMTIQPSFNN AHVSKFSDQN STELMNSVMV RTEEEIADTD 
LKQEEPPSDL ASAYVTEDLE SPTIVHQVHQ TIDDETILIV PSPHGFIQAS DVIDTESVLP 
LTTLTDPIFQ HHQEASNIIG SSLGSPVSED SKDVEDLVNC H

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.