Genular: Defining Cellular Identity and Function

Details for: Ggt5

Gene ID: 23887

Symbol: Ggt5

Ensembl ID: ENSMUSG00000006344

Description: gamma-glutamyltransferase 5

Associated with

Aflatoxin activation and detoxification
(R-MMU-5423646)
Arachidonic acid metabolism
(R-MMU-2142753)
Biological oxidations
(R-MMU-211859)
Drug adme
(R-MMU-9748784)
Fatty acid metabolism
(R-MMU-8978868)
Glutathione conjugation
(R-MMU-156590)
Glutathione synthesis and recycling
(R-MMU-174403)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Paracetamol adme
(R-MMU-9753281)
Phase ii - conjugation of compounds
(R-MMU-156580)
Synthesis of leukotrienes (lt) and eoxins (ex)
(R-MMU-2142691)
Acyltransferase activity
(GO:0016746)
Amino acid metabolic process
(GO:0006520)
Fatty acid metabolic process
(GO:0006631)
Glutathione biosynthetic process
(GO:0006750)
Glutathione catabolic process
(GO:0006751)
Glutathione hydrolase activity
(GO:0036374)
Hydrolase activity
(GO:0016787)
Inflammatory response
(GO:0006954)
Leukotriene-c(4) hydrolase
(GO:0002951)
Leukotriene biosynthetic process
(GO:0019370)
Leukotriene c4 gamma-glutamyl transferase activity
(GO:0103068)
Leukotriene d4 biosynthetic process
(GO:1901750)
Membrane
(GO:0016020)
Peptidase activity
(GO:0008233)
Peptidyltransferase activity
(GO:0000048)
Plasma membrane
(GO:0005886)
Proteolysis
(GO:0006508)
Transferase activity
(GO:0016740)

Other Information

Proteins

Glutathione hydrolase 5 proenzyme

Genular Protein ID: 1303314252

Symbol: GGT5_MOUSE

Name: Glutathione hydrolase 5 proenzyme

UniProtKB Accession Codes:

Q9Z2A9 Q8C7B4

Database IDs:

Citations:

PubMed ID: 9774450

Title: Gamma-glutamyl leukotrienase, a gamma-glutamyl transpeptidase gene family member, is expressed primarily in spleen.

PubMed ID: 9774450

DOI: 10.1074/jbc.273.43.28277

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 11463821

Title: Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response.

PubMed ID: 11463821

DOI: 10.1128/mcb.21.16.5389-5395.2001

PubMed ID: 12163373

Title: Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.

PubMed ID: 12163373

DOI: 10.1016/s0002-9440(10)64204-6

Sequence Information:

Length: 573
Mass: 61674
Checksum: CB00F377DA1BE83E
Sequence:

MAWGHRATVC LVLLGVGLGL VIVVLAAVLS PRQASCGPGA FTRAAVAADS KICSDIGRAI 
LQQRGSPVDA AIAALVCTGV VNPQSMGLGG GVVFTIYNAS TGKVEIINAR ETVPASYDQG 
LLNQCKNVLP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL REGFRVPFIL 
SQFLNNSILR PHLSASTLRQ LFFNGTETLR SQDPFPWPAL ANTLETVAKE GAEVLYTGRL 
GRMLVEDIAK QGSLLTVQDL AAFQPEVVEP LEMPLGNYTL YSPPPPAGGA ILSFILNVLK 
GFNFSAETVA RPGGEVNMYH HLVETLKFAV GQRWRLWDPS SHPGIQNISR DLLREDLAQR 
IRQQIDGRGD HHQLSHYNLT GVRGNRMGTS HVSVLGEDGS AVAATSTINT PFGAMVYSPR 
TGILLNNELL DLCWRHMPTS PITPPPVPGE RPPSSMVPSI LVNKGQGSKL VIGGAGGELI 
ISAVAQTIMN KLWLGFDLTE AIASPILHVN SKGHVEYEPK FNQEVQKGLQ DRGQIQSQSQ 
RPVFLNAVQA VFQEGPCVYA ASDLRKAGKA SGY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ggt5

Associated with

Other Information

Gamma-glutamyl leukotrienase, a gamma-glutamyl transpeptidase gene family member, is expressed primarily in spleen. PubMed ID: 9774450

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response. PubMed ID: 11463821

Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo. PubMed ID: 12163373