Details for: Hcst

Gene ID: 23900

Symbol: Hcst

Ensembl ID: ENSMUSG00000064109

Description: hematopoietic cell signal transducer

Associated with

Other Information

Genular Protein ID: 2532786998

Symbol: HCST_MOUSE

Name: Hematopoietic cell signal transducer

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10528161

Title: KAP10, a novel transmembrane adapter protein genetically linked to DAP12 but with unique signaling properties.

PubMed ID: 10528161

PubMed ID: 10426994

Title: An activating immunoreceptor complex formed by NKG2D and DAP10.

PubMed ID: 10426994

DOI: 10.1126/science.285.5428.730

PubMed ID: 11491539

Title: The mouse Dap10 gene.

PubMed ID: 11491539

DOI: 10.1007/s002510100333

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12426565

Title: Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D.

PubMed ID: 12426565

DOI: 10.1038/ni858

PubMed ID: 12426564

Title: NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation.

PubMed ID: 12426564

DOI: 10.1038/ni857

PubMed ID: 15365099

Title: Differential requirements for Vav proteins in DAP10- and ITAM-mediated NK cell cytotoxicity.

PubMed ID: 15365099

DOI: 10.1084/jem.20031847

PubMed ID: 15294961

Title: A Structural basis for the association of DAP12 with mouse, but not human, NKG2D.

PubMed ID: 15294961

DOI: 10.4049/jimmunol.173.4.2470

PubMed ID: 16086018

Title: Function of NKG2D in natural killer cell-mediated rejection of mouse bone marrow grafts.

PubMed ID: 16086018

DOI: 10.1038/ni1236

PubMed ID: 17100879

Title: Physiological roles of murine DAP10 adapter protein in tumor immunity and autoimmunity.

PubMed ID: 17100879

DOI: 10.1111/j.1600-065x.2006.00456.x

PubMed ID: 16887996

Title: Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics.

PubMed ID: 16887996

DOI: 10.4049/jimmunol.177.4.2349

PubMed ID: 17785813

Title: DAP10 deficiency breaks the immune tolerance against transplantable syngeneic melanoma.

PubMed ID: 17785813

DOI: 10.4049/jimmunol.179.6.3763

PubMed ID: 19251634

Title: Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12.

PubMed ID: 19251634

DOI: 10.1073/pnas.0900463106

Sequence Information:

  • Length: 79
  • Mass: 8114
  • Checksum: B411985277D601E3
  • Sequence:
  • MDPPGYLLFL LLLPVAASQT SAGSCSGCGT LSLPLLAGLV AADAVMSLLI VGVVFVCMRP 
    HGRPAQEDGR VYINMPGRG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.