Genular: Defining Cellular Identity and Function

Details for: Nr2e3

Gene ID: 23958

Symbol: Nr2e3

Ensembl ID: ENSMUSG00000032292

Description: nuclear receptor subfamily 2, group E, member 3

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Nuclear receptor transcription pathway
(R-MMU-383280)
Rna polymerase ii transcription
(R-MMU-73857)
Anatomical structure development
(GO:0048856)
Cell differentiation
(GO:0030154)
Cell population proliferation
(GO:0008283)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna binding
(GO:0003677)
Eye photoreceptor cell development
(GO:0042462)
Metal ion binding
(GO:0046872)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear receptor activity
(GO:0004879)
Nucleus
(GO:0005634)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Retina development in camera-type eye
(GO:0060041)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Transcription regulator complex
(GO:0005667)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Photoreceptor-specific nuclear receptor

Genular Protein ID: 3309064045

Symbol: NR2E3_MOUSE

Name: Photoreceptor-specific nuclear receptor

UniProtKB Accession Codes:

Q9QXZ7

Database IDs:

Citations:

PubMed ID: 10611353

Title: Retina-specific nuclear receptor: a potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Muller glial cells.

PubMed ID: 10611353

DOI: 10.1073/pnas.96.26.15149

PubMed ID: 10805811

Title: A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse.

PubMed ID: 10805811

DOI: 10.1073/pnas.97.10.5551

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15190009

Title: Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors.

PubMed ID: 15190009

DOI: 10.1093/hmg/ddh173

PubMed ID: 15634773

Title: The rod photoreceptor-specific nuclear receptor Nr2e3 represses transcription of multiple cone-specific genes.

PubMed ID: 15634773

DOI: 10.1523/jneurosci.3571-04.2005

PubMed ID: 19186166

Title: Pias3-dependent SUMOylation directs rod photoreceptor development.

PubMed ID: 19186166

DOI: 10.1016/j.neuron.2008.12.006

PubMed ID: 21408158

Title: Nuclear receptor Rev-erb alpha (Nr1d1) functions in concert with Nr2e3 to regulate transcriptional networks in the retina.

PubMed ID: 21408158

DOI: 10.1371/journal.pone.0017494

Sequence Information:

Length: 395
Mass: 43177
Checksum: D8E391CF24919A68
Sequence:

MSSTVAASTM PVSVAASKKE SPGRWGLGED PTGVGPSLQC RVCGDSSSGK HYGIYACNGC 
SGFFKRSVRR RLIYRCQVGA GMCPVDKAHR NQCQACRLKK CLQAGMNQDA VQNERQPRSM 
AQVHLDAMET GSDPRSEPVV ASPALAGPSP RGPTSVSATR AMGHHFMASL ITAETCAKLE 
PEDAEENIDV TSNDPEFPAS PCSLDGIHET SARLLFMAVK WAKNLPVFSN LPFRDQVILL 
EEAWNELFLL GAIQWSLPLD SCPLLAPPEA SGSSQGRLAL ASAETRFLQE TISRFRALAV 
DPTEFACLKA LVLFKPETRG LKDPEHVEAL QDQSQVMLSQ HSKAHHPSQP VRFGKLLLLL 
PSLRFLTAER IELLFFRKTI GNTPMEKLLC DMFKN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nr2e3

Associated with

Other Information

Retina-specific nuclear receptor: a potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Muller glial cells. PubMed ID: 10611353

A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse. PubMed ID: 10805811

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors. PubMed ID: 15190009

The rod photoreceptor-specific nuclear receptor Nr2e3 represses transcription of multiple cone-specific genes. PubMed ID: 15634773

Pias3-dependent SUMOylation directs rod photoreceptor development. PubMed ID: 19186166

Nuclear receptor Rev-erb alpha (Nr1d1) functions in concert with Nr2e3 to regulate transcriptional networks in the retina. PubMed ID: 21408158