Genular: Defining Cellular Identity and Function

Details for: Prkra

Gene ID: 23992

Symbol: Prkra

Ensembl ID: ENSMUSG00000002731

Description: protein kinase, interferon inducible double stranded RNA dependent activator

Associated with

Antiviral mechanism by ifn-stimulated genes
(R-MMU-1169410)
Cytokine signaling in immune system
(R-MMU-1280215)
Gene expression (transcription)
(R-MMU-74160)
Gene silencing by rna
(R-MMU-211000)
Immune system
(R-MMU-168256)
Interferon signaling
(R-MMU-913531)
Microrna (mirna) biogenesis
(R-MMU-203927)
Pkr-mediated signaling
(R-MMU-9833482)
Small interfering rna (sirna) biogenesis
(R-MMU-426486)
Cellular response to oxidative stress
(GO:0034599)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Double-stranded rna binding
(GO:0003725)
Ear development
(GO:0043583)
Enzyme binding
(GO:0019899)
Identical protein binding
(GO:0042802)
Intracellular anatomical structure
(GO:0005622)
Middle ear morphogenesis
(GO:0042474)
Mirna processing
(GO:0035196)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Outer ear morphogenesis
(GO:0042473)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of intrinsic apoptotic signaling pathway
(GO:2001244)
Pre-mirna binding
(GO:0070883)
Pre-mirna processing
(GO:0031054)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein kinase binding
(GO:0019901)
Protein phosphorylation
(GO:0006468)
Protein stabilization
(GO:0050821)
Regulation of regulatory ncrna processing
(GO:0070920)
Regulatory ncrna-mediated gene silencing
(GO:0031047)
Risc-loading complex
(GO:0070578)
Risc complex
(GO:0016442)
Risc complex assembly
(GO:0070922)
Rna binding
(GO:0003723)
Sirna binding
(GO:0035197)
Sirna processing
(GO:0030422)
Skeletal system morphogenesis
(GO:0048705)

Other Information

Proteins

Interferon-inducible double-stranded RNA-dependent protein kinase activator A

Genular Protein ID: 1601594198

Symbol: PRKRA_MOUSE

Name: Interferon-inducible double-stranded RNA-dependent protein kinase activator A

UniProtKB Accession Codes:

Q9WTX2 Q9CZB7

Database IDs:

Citations:

PubMed ID: 10336432

Title: RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling.

PubMed ID: 10336432

DOI: 10.1074/jbc.274.22.15427

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22214662

Title: The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G(1) arrest.

PubMed ID: 22214662

DOI: 10.4161/cc.11.2.18999

Sequence Information:

Length: 313
Mass: 34371
Checksum: 6EDF248A55A391D2
Sequence:

MSHSRHRAEA PPLQREDSGT FSLGKMITAK PGKTPIQVLH EYGMKTKNIP VYECERSDVQ 
VHVPTFTFRV TVGDITCTGE GTSKKLAKHR AAEAAINILK ANASICFAVP DPLMPDPSKQ 
PKNQLNPIGS LQELAIHHGW RLPEYTLSQE GGPAHKREYT TICRLESFME TGKGASKKQA 
KRNAAEKFLA KFSNISPENH ISLTNVVGHS LGCTWHSLRN SPGEKINLLK RSLLSLPNTD 
YIQLLSEIAS EQGFNITYLD IEELSANGQY QCLAELSTSP ITVCHGSGIS CGNAQSDAAH 
NALQYLKIIA ERK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Prkra

Associated with

Other Information

RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling. PubMed ID: 10336432

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334