Genular: Defining Cellular Identity and Function

Details for: Slc35a1

Gene ID: 24060

Symbol: Slc35a1

Ensembl ID: ENSMUSG00000028293

Description: solute carrier family 35 (CMP-sialic acid transporter), member 1

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-MMU-446193)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Sialic acid metabolism
(R-MMU-4085001)
Slc-mediated transmembrane transport
(R-MMU-425407)
Synthesis of substrates in n-glycan biosythesis
(R-MMU-446219)
Transport of nucleotide sugars
(R-MMU-727802)
Transport of small molecules
(R-MMU-382551)
Transport of vitamins, nucleosides, and related molecules
(R-MMU-425397)
Antiporter activity
(GO:0015297)
Carbohydrate transport
(GO:0008643)
Cmp-n-acetylneuraminate transmembrane transport
(GO:0015782)
Cmp-n-acetylneuraminate transmembrane transporter activity
(GO:0005456)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Membrane
(GO:0016020)
Pyrimidine nucleotide-sugar transmembrane transport
(GO:0090481)
Pyrimidine nucleotide-sugar transmembrane transporter activity
(GO:0015165)

Other Information

Proteins

Solute carrier family 35 member A1

Genular Protein ID: 1557772470

Symbol: S35A1_MOUSE

Name: Solute carrier family 35 member A1

UniProtKB Accession Codes:

Q61420 A2AT44

Database IDs:

Citations:

PubMed ID: 8755516

Title: Expression cloning of the Golgi CMP-sialic acid transporter.

PubMed ID: 8755516

DOI: 10.1073/pnas.93.15.7572

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10085119

Title: Membrane topology of the mammalian CMP-sialic acid transporter.

PubMed ID: 10085119

DOI: 10.1074/jbc.274.13.8779

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 34015330

Title: The promiscuous binding pocket of SLC35A1 ensures redundant transport of CDP-ribitol to the Golgi.

PubMed ID: 34015330

DOI: 10.1016/j.jbc.2021.100789

PubMed ID: 15932921

Title: Endoplasmic reticulum retention of the large splice variant of the UDP-galactose transporter is caused by a dilysine motif.

PubMed ID: 15932921

DOI: 10.1093/glycob/cwi085

PubMed ID: 30985278

Title: Structural basis for mammalian nucleotide sugar transport.

PubMed ID: 30985278

DOI: 10.7554/elife.45221

Sequence Information:

Length: 336
Mass: 36453
Checksum: A396528233904451
Sequence:

MAPARENVSL FFKLYCLTVM TLVAAAYTVA LRYTRTTAEE LYFSTTAVCI TEVIKLLISV 
GLLAKETGSL GRFKASLSEN VLGSPKELAK LSVPSLVYAV QNNMAFLALS NLDAAVYQVT 
YQLKIPCTAL CTVLMLNRTL SKLQWISVFM LCGGVTLVQW KPAQATKVVV AQNPLLGFGA 
IAIAVLCSGF AGVYFEKVLK SSDTSLWVRN IQMYLSGIVV TLAGTYLSDG AEIQEKGFFY 
GYTYYVWFVI FLASVGGLYT SVVVKYTDNI MKGFSAAAAI VLSTIASVLL FGLQITLSFA 
LGALLVCVSI YLYGLPRQDT TSIQQEATSK ERIIGV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc35a1

Associated with

Other Information

Expression cloning of the Golgi CMP-sialic acid transporter. PubMed ID: 8755516

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Membrane topology of the mammalian CMP-sialic acid transporter. PubMed ID: 10085119

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The promiscuous binding pocket of SLC35A1 ensures redundant transport of CDP-ribitol to the Golgi. PubMed ID: 34015330

Endoplasmic reticulum retention of the large splice variant of the UDP-galactose transporter is caused by a dilysine motif. PubMed ID: 15932921

Structural basis for mammalian nucleotide sugar transport. PubMed ID: 30985278