Genular: Defining Cellular Identity and Function

Details for: Smc1a

Gene ID: 24061

Symbol: Smc1a

Ensembl ID: ENSMUSG00000041133

Description: structural maintenance of chromosomes 1A

Associated with

Cell cycle, mitotic
(R-MMU-69278)
Cohesin loading onto chromatin
(R-MMU-2470946)
Establishment of sister chromatid cohesion
(R-MMU-2468052)
Metabolism of proteins
(R-MMU-392499)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prometaphase
(R-MMU-68877)
Mitotic telophase/cytokinesis
(R-MMU-68884)
M phase
(R-MMU-68886)
Post-translational protein modification
(R-MMU-597592)
Resolution of sister chromatid cohesion
(R-MMU-2500257)
Separation of sister chromatids
(R-MMU-2467813)
S phase
(R-MMU-69242)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of dna damage response and repair proteins
(R-MMU-3108214)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Chromatin binding
(GO:0003682)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Chromosome organization
(GO:0051276)
Cohesin complex
(GO:0008278)
Cytosol
(GO:0005829)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna repair
(GO:0006281)
Kinetochore
(GO:0000776)
Lateral element
(GO:0000800)
Mediator complex binding
(GO:0036033)
Meiotic cell cycle
(GO:0051321)
Meiotic cohesin complex
(GO:0030893)
Mitotic cohesin complex
(GO:0030892)
Mitotic spindle assembly
(GO:0090307)
Mitotic spindle pole
(GO:0097431)
Nuclear matrix
(GO:0016363)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Response to dna damage checkpoint signaling
(GO:0072423)
Sister chromatid cohesion
(GO:0007062)
Somatic stem cell population maintenance
(GO:0035019)
Synaptonemal complex
(GO:0000795)

Other Information

Proteins

Structural maintenance of chromosomes protein 1A

Genular Protein ID: 3809568015

Symbol: SMC1A_MOUSE

Name: Structural maintenance of chromosomes protein 1A

UniProtKB Accession Codes:

Q9CU62 A2AFQ5 Q3V480 Q9CUX9 Q9D959 Q9WTU1

Database IDs:

Citations:

PubMed ID: 10375619

Title: Characterization of the components of the putative mammalian sister chromatid cohesion complex.

PubMed ID: 10375619

DOI: 10.1016/s0378-1119(99)00160-2

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 11483963

Title: Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I.

PubMed ID: 11483963

DOI: 10.1038/35087082

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22977523

Title: Functional interaction of BRCA1/ATM-associated BAAT1 with the DNA-PK catalytic subunit.

PubMed ID: 22977523

DOI: 10.3892/etm.2011.232

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 1233
Mass: 143235
Checksum: E62CEB174854D9A6
Sequence:

MGFLKLIEIE NFKSYKGRQI IGPFQRFTAI IGPNGSGKSN LMDAISFVLG EKTSNLRVKT 
LRDLIHGAPV GKPAANRAFV SMVYSEEGAE DRTFARVIVG GSSEYKINNK VVQLHEYSEE 
LEKLGILIKA RNFLVFQGAV ESIAMKNPKE RTALFEEISR SGELAQEYDK RKKEMVKAEE 
DTQFNYHRKK NIAAERKEAK QEKEEADRYQ RLKDEVVRAQ VQLQLFKLYH NEVEIEKLNK 
ELASKNKEIE KDKKRMDKVE DELKEKKKEL GKMMREQQQI EKEIKEKDSE LNQKRPQYIK 
AKENTSHKIK KLEAAKKSLQ NAQKHYKKRK GDMDELEKEM LSVEKARQEF EERMEEESQS 
QGRDLTLEEN QVKKYHRLKE EASKRAATLA QELEKFNRDQ KADQDRLDLE ERKKVETEAK 
IKQKLREIEE NQKRIEKLEE YITTSKQSLE EQKKLEGELT EEVEMAKRRI DEINKELNQV 
MEQLGDARID RQESSRQQRK AEIMESIKRL YPGSVYGRLI DLCQPTQKKY QIAVTKVLGK 
NMDAIIVDSE KTGRDCIQYI KEQRGEPETF LPLDYLEVKP TDEKLRELKG AKLVIDVIRY 
EPPHIKKALQ YACGNALVCD NVEDARRIAF GGHQRHKTVA LDGTLFQKSG VISGGASDLK 
AKARRWDEKA VDKLKEKKER LTEELKEQMK AKRKEAELRQ VQSQAHGLQM RLKYSQSDLE 
QTKTRHLALN LQEKSKLESE LANFGPRIND IKRIIQSRER EMKDLKEKMN QVEDEVFEEF 
CREIGVRNIR EFEEEKVKRQ NEIAKKRLEF ENQKTRLGIQ LDFEKNQLKE DQDKVHMWEQ 
TVKKDENEIE KLKKEEQRHM KIIDETMAQL QDLKNQHLAK KSEVNDKNHE MEEIRKKLGG 
ANKEMTHLQK EVTAIETKLE QKRSDRHNLL QACKMQDIKL PLSKGTMDDI SQEEGSSQGE 
ESVSGSQRTS SIYAREALIE IDYGDLCEDL KDAQAEEEIK QEMNTLQQKL NEQQSVLQRI 
AAPNMKAMEK LESVRDKFQE TSDEFEAARK RAKKAKQAFE QIKKERFDRF NACFESVATN 
IDEIYKALSR NSSAQAFLGP ENPEEPYLDG INYNCVAPGK RFRPMDNLSG GEKTVAALAL 
LFAIHSYKPA PFFVLDEIDA ALDNTNIGKV ANYIKEQSTC NFQAIVISLK EEFYTKAESL 
IGVYPEQGDC VISKVLTFDL TKYPDANPNP NEQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Smc1a

Associated with

Other Information

Characterization of the components of the putative mammalian sister chromatid cohesion complex. PubMed ID: 10375619

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I. PubMed ID: 11483963

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Functional interaction of BRCA1/ATM-associated BAAT1 with the DNA-PK catalytic subunit. PubMed ID: 22977523

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337