Genular: Defining Cellular Identity and Function

Details for: Rbck1

Gene ID: 24105

Symbol: Rbck1

Ensembl ID: ENSMUSG00000027466

Description: RanBP-type and C3HC4-type zinc finger containing 1

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-MMU-983168)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Death receptor signaling
(R-MMU-73887)
Immune system
(R-MMU-168256)
Regulation of tnfr1 signaling
(R-MMU-5357905)
Signal transduction
(R-MMU-162582)
Tnfr1-induced nf-kappa-b signaling pathway
(R-MMU-5357956)
Tnfr1-induced proapoptotic signaling
(R-MMU-5357786)
Tnf signaling
(R-MMU-75893)
Cytoplasmic sequestering of protein
(GO:0051220)
Defense response to bacterium
(GO:0042742)
Double-stranded dna binding
(GO:0003690)
Identical protein binding
(GO:0042802)
Lubac complex
(GO:0071797)
Metal ion binding
(GO:0046872)
Negative regulation of necroptotic process
(GO:0060546)
Negative regulation of nf-kappab transcription factor activity
(GO:0032088)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of extrinsic apoptotic signaling pathway
(GO:2001238)
Positive regulation of nf-kappab transcription factor activity
(GO:0051092)
Positive regulation of non-canonical nf-kappab signal transduction
(GO:1901224)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein binding
(GO:0005515)
Protein kinase c binding
(GO:0005080)
Protein linear polyubiquitination
(GO:0097039)
Protein polyubiquitination
(GO:0000209)
Protein sequestering activity
(GO:0140311)
T cell receptor signaling pathway
(GO:0050852)
Transcription coactivator activity
(GO:0003713)
Transferase activity
(GO:0016740)
Tumor necrosis factor-mediated signaling pathway
(GO:0033209)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin binding
(GO:0043130)
Ubiquitin ligase activator activity
(GO:1990757)

Other Information

Proteins

RanBP-type and C3HC4-type zinc finger-containing protein 1

Genular Protein ID: 10029133

Symbol: HOIL1_MOUSE

Name: RanBP-type and C3HC4-type zinc finger-containing protein 1

UniProtKB Accession Codes:

Q9WUB0 A2ANR4 Q3TM86 Q8C2I0

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10431818

Title: A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4.

PubMed ID: 10431818

DOI: 10.1016/s0014-5793(99)00823-6

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 19136968

Title: Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.

PubMed ID: 19136968

DOI: 10.1038/ncb1821

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20956555

Title: Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development.

PubMed ID: 20956555

DOI: 10.1128/mcb.01645-09

PubMed ID: 22139374

Title: Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex.

PubMed ID: 22139374

DOI: 10.1073/pnas.1109088108

Sequence Information:

Length: 508
Mass: 57534
Checksum: CBD3B40CD4E55180
Sequence:

MDEKTKKAEE MALSLARAVA GGDEQAAIKY ATWLAEQRVP LRVQVKPEVS PTQDIRLCVS 
VEDAYMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPSLQQ WVVGQRLARD QETLHSHGIR 
RNGDGAYLYL LSARNTSLNP QELQRQRQLR MLEDLGFKDL TLQSRGPLEP VLPKPRTNQE 
PGQPDAAPES PPVGWQCPGC TFINKPTRPG CEMCCRARPE TYQIPASYQP DEEERARLAG 
EEEALRQYQQ RKQQQQEGNY LQHVQLEQRS LVLNTEPTEC PVCYSVLAPG EAVVLRECLH 
TFCRECLQGT IRNSQEAEVA CPFIDSTYSC PGKLLEREIR ALLSPEDYQR FLDLGVSIAE 
NRSTLSYHCK TPDCRGWCFF EDDVNEFTCP VCTRVNCLLC KAIHEHMNCR EYQDDLALRA 
QNDVAARQTT EMLKVMLQQG EAMHCPQCRI VVQKKDGCDW IRCTVCHTEI CWVTKGPRWG 
PGGPGDTSGG CRCRVNGIPC HPSCQNCH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rbck1

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4. PubMed ID: 10431818

Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. PubMed ID: 17947660

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. PubMed ID: 19136968

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development. PubMed ID: 20956555

Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex. PubMed ID: 22139374