Genular: Defining Cellular Identity and Function

Details for: Vax2

Gene ID: 24113

Symbol: Vax2

Ensembl ID: ENSMUSG00000034777

Description: ventral anterior homeobox 2

Associated with

Axonogenesis
(GO:0007409)
Brain development
(GO:0007420)
Camera-type eye development
(GO:0043010)
Central nervous system development
(GO:0007417)
Chromatin dna binding
(GO:0031490)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Dorsal/ventral axis specification
(GO:0009950)
Embryonic eye morphogenesis
(GO:0048048)
Forebrain development
(GO:0030900)
Multicellular organism development
(GO:0007275)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuron differentiation
(GO:0030182)
Nucleus
(GO:0005634)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Retina development in camera-type eye
(GO:0060041)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii intronic transcription regulatory region sequence-specific dna binding
(GO:0001162)
Sequence-specific double-stranded dna binding
(GO:1990837)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Ventral anterior homeobox 2

Genular Protein ID: 584167575

Symbol: VAX2_MOUSE

Name: Ventral anterior homeobox 2

UniProtKB Accession Codes:

Q9WTP9

Database IDs:

Citations:

PubMed ID: 10421837

Title: Expression of the Vax family homeobox genes suggests multiple roles in eye development.

PubMed ID: 10421837

DOI: 10.1046/j.1365-2443.1999.00257.x

PubMed ID: 10485894

Title: A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis.

PubMed ID: 10485894

DOI: 10.1073/pnas.96.19.10729

PubMed ID: 10595508

Title: Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map.

PubMed ID: 10595508

DOI: 10.1016/s0896-6273(00)81111-3

PubMed ID: 11830578

Title: The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye.

PubMed ID: 11830578

DOI: 10.1242/dev.129.3.797

PubMed ID: 21856776

Title: A novel mechanism for the transcriptional regulation of Wnt signaling in development.

PubMed ID: 21856776

DOI: 10.1101/gad.17227011

Sequence Information:

Length: 292
Mass: 31701
Checksum: C6A76B7BB799445D
Sequence:

MGDGGAERDR GPKRREEPGG RSGRHGEHRG AEDLRADTGS ASPREIAGTS ASSPAGSRES 
GGDSDGQQAL GETDHCRRIL VRDAKGTIRE IVLPKGLDLD RPKRTRTSFT AEQLYRLEME 
FQRCQYVVGR ERTELARQLN LSETQVKVWF QNRRTKQKKD QSRDLEKRAS SSASEAFATS 
NVLRLLEQGR LLSVPRAPSL LALTPGLPGL PASHRGTSLV DPRNSSPRLN PMPSASASSP 
LPPPLPAICF SSAPLLDLPA GYKLGSSAFE PYSRLEQQKV GSPGQSDKKA DI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vax2

Associated with

Other Information

Expression of the Vax family homeobox genes suggests multiple roles in eye development. PubMed ID: 10421837

A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis. PubMed ID: 10485894

Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map. PubMed ID: 10595508