Genular: Defining Cellular Identity and Function

Details for: Best1

Gene ID: 24115

Symbol: Best1

Ensembl ID: ENSMUSG00000037418

Description: bestrophin 1

Associated with

Ion channel transport
(R-MMU-983712)
Stimuli-sensing channels
(R-MMU-2672351)
Transport of small molecules
(R-MMU-382551)
Basal plasma membrane
(GO:0009925)
Basolateral plasma membrane
(GO:0016323)
Chloride channel activity
(GO:0005254)
Chloride channel complex
(GO:0034707)
Chloride transport
(GO:0006821)
Detection of light stimulus involved in visual perception
(GO:0050908)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Plasma membrane
(GO:0005886)
Regulation of calcium ion transport
(GO:0051924)
Transepithelial chloride transport
(GO:0030321)

Other Information

Proteins

Bestrophin-1

Genular Protein ID: 897320384

Symbol: BEST1_MOUSE

Name: Bestrophin-1

UniProtKB Accession Codes:

O88870 B2RSY6 Q6H1V0

Database IDs:

Citations:

PubMed ID: 15218265

Title: Cloning and characterization of the murine Vmd2 RFP-TM gene family.

PubMed ID: 15218265

DOI: 10.1159/000078016

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9662395

Title: Identification of the gene responsible for Best macular dystrophy.

PubMed ID: 9662395

DOI: 10.1038/915

Sequence Information:

Length: 551
Mass: 63684
Checksum: 0898D6DE08FEEFB9
Sequence:

MTITYTNKVA NARLGSFSSL LLCWRGSIYK LLYGEFLVFI FLYYSIRGLY RMVLSSDQQL 
LFEKLALYCD SYIQLIPISF VLGFYVTLVV SRWWSQYENL PWPDRLMIQV SSFVEGKDEE 
GRLLRRTLIR YAILGQVLIL RSISTSVYKR FPTLHHLVLA GFMTHGEHKQ LQKLGLPHNT 
FWVPWVWFAN LSMKAYLGGR IRDTVLLQSL MNEVCTLRTQ CGQLYAYDWI SIPLVYTQVV 
TVAVYSFFLA CLIGRQFLNP NKDYPGHEMD LVVPVFTILQ FLFYMGWLKV AEQLINPFGE 
DDDDFETNWI IDRNLQVSLL SVDGMHQNLP PMERDMYWNE AAPQPPYTAA SARSRRHSFM 
GSTFNISLKK EDLELWSKEE ADTDKKESGY SSTIGCFLGL QPKNYHLPLK DLKTKLLCSK 
NPLLEGQCKD ANQKNQKDVW KFKGLDFLKC VPRFKRRGSH CGPQAPSSHP TEQSAPSSSD 
TGDGPSTDYQ EICHMKKKTV EFNLNIPESP TEHLQQRRLD QMSTNIQALM KEHAESYPYR 
DEAGTKPVLY E

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.