Genular: Defining Cellular Identity and Function

Details for: Xrn2

Gene ID: 24128

Symbol: Xrn2

Ensembl ID: ENSMUSG00000027433

Description: 5'-3' exoribonuclease 2

Associated with

Major pathway of rrna processing in the nucleolus and cytosol
(R-MMU-6791226)
Metabolism of rna
(R-MMU-8953854)
Rrna processing
(R-MMU-72312)
Rrna processing in the nucleus and cytosol
(R-MMU-8868773)
3'-5'-rna exonuclease activity
(GO:0000175)
5'-3' exonuclease activity
(GO:0008409)
5'-3' rna exonuclease activity
(GO:0004534)
Aggresome
(GO:0016235)
Dna-templated transcription termination
(GO:0006353)
Dna binding
(GO:0003677)
Dna recombination
(GO:0006310)
Dna repair
(GO:0006281)
Exonuclease activity
(GO:0004527)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
Metal ion binding
(GO:0046872)
Microtubule-based process
(GO:0007017)
Mrna processing
(GO:0006397)
Nuclear-transcribed mrna catabolic process
(GO:0000956)
Nuclease activity
(GO:0004518)
Nucleic acid binding
(GO:0003676)
Nucleobase-containing compound metabolic process
(GO:0006139)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Rna binding
(GO:0003723)
Rna metabolic process
(GO:0016070)
Spermatogenesis
(GO:0007283)
Termination of rna polymerase ii transcription
(GO:0006369)
Transcription termination site sequence-specific dna binding
(GO:0001147)

Other Information

Proteins

5'-3' exoribonuclease 2

Genular Protein ID: 3713586004

Symbol: XRN2_MOUSE

Name: 5'-3' exoribonuclease 2

UniProtKB Accession Codes:

Q9DBR1 Q3TI26 Q3TKF2 Q3UZT9 Q61489 Q99KS7

Database IDs:

Citations:

PubMed ID: 7885830

Title: Characterization of cDNA encoding mouse homolog of fission yeast dhp1+ gene: structural and functional conservation.

PubMed ID: 7885830

DOI: 10.1093/nar/23.3.357

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18630941

Title: Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.

PubMed ID: 18630941

DOI: 10.1021/pr800223m

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 951
Mass: 108687
Checksum: CF57479291DD18B9
Sequence:

MGVPAFFRWL SRKYPSIIVN CVEEKPKECN GVKIPVDASK PNPNDVEFDN LYLDMNGIIH 
PCTHPEDKPA PKNEDEMMVA IFEYIDRLFN IVRPRRLLYM AIDGVAPRAK MNQQRSRRFR 
ASKEGMEAAV EKQRVREEIL AKGGFLPPEE IKERFDSNCI TPGTEFMDNL AKCLRYYIAD 
RLNNDPGWKN LTVILSDASA PGEGEHKIMD YIRRQRAQPN HDPNTHHCLC GADADLIMLG 
LATHEPNFTI IREEFKPNKP KPCALCNQFG HEVKDCEGLP REKKGKHDEL ADSLPCAEGE 
FIFLRLNVLR EYLERELTMA SLPFPFDVER SIDDWVFMCF FVGNDFLPHL PSLEIREGAI 
DRLVNIYKNV VHKTGGYLTE SGYVNLQRVQ MIMLAVGEVE DSIFKKRKDD EDSFRRRQKE 
KRKRMKRDQP AFTPSGILTP HALGSRNSPG CQVASNPRQA AYEMRMQRNS SPSISPNTSF 
ASDGSPSPLG GIKRKAEDSD SEPEPEDNVR LWEAGWKQRY YKNKFDVDAA DEKFRRKVVQ 
SYVEGLCWVL RYYYQGCASW KWYYPFHYAP FASDFEGIAD MSSEFEKGTK PFKPLEQLMG 
VFPAASGNFL PPTWRKLMSD PDSSIIDFYP EDFAIDLNGK KYAWQGVALL PFVDERRLRA 
ALEEVYPDLT PEENRRNSLG GDVLFVGKLH PLRDFILELY QTGSTEPVDV PPELCHGIQG 
TFSLDEEAIL PDQTVCSPVP MLRDLTQNTA VSINFKDPQF AEDYVFKAAM LPGARKPATV 
LKPGDWEKSS NGRQWKPQLG FNRDRRPVHL DQAAFRTLGH VTPRGSGTSV YTNTALPPAN 
YQGNNYRPLL RGQAQIPKLM SNMRPQDSWR GPPPLFQQHR FERSVGAEPL LPWNRMIQNQ 
NAAFQPNQYQ MLGGPGGYPP RRDDHRGGRQ GYPREGRKYP LPPPSGRYSW N

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Xrn2

Associated with

Other Information

Characterization of cDNA encoding mouse homolog of fission yeast dhp1+ gene: structural and functional conservation. PubMed ID: 7885830

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis. PubMed ID: 18630941

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315