Details for: KIF4A
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 3.81
Marker Score: 32,182 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 2.47
Marker Score: 7,034 - Cell Name: T-helper 17 cell (CL0000899)
Fold Change: 1.99
Marker Score: 1,306 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 1.65
Marker Score: 742 - Cell Name: mural cell (CL0008034)
Fold Change: 1.48
Marker Score: 169,391 - Cell Name: germ cell (CL0000586)
Fold Change: 1.09
Marker Score: 1,905 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.01
Marker Score: 2,747 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,813 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,038 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,408 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 503 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 457 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,411 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,736 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.91
Marker Score: 1,101 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.9
Marker Score: 5,127 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 323 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 0.88
Marker Score: 825 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,296 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.82
Marker Score: 559 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,259 - Cell Name: Unknown (CL0000548)
Fold Change: 0.76
Marker Score: 552 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 392 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.75
Marker Score: 300 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.72
Marker Score: 1,367 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.72
Marker Score: 551 - Cell Name: brush cell (CL0002204)
Fold Change: 0.71
Marker Score: 645 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.7
Marker Score: 2,937 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.7
Marker Score: 525 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 177 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.61
Marker Score: 342 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.6
Marker Score: 1,212 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.6
Marker Score: 636 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.59
Marker Score: 782 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 443 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.55
Marker Score: 786 - Cell Name: mature B cell (CL0000785)
Fold Change: 0.54
Marker Score: 395 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.53
Marker Score: 1,567 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.52
Marker Score: 166 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 0.51
Marker Score: 250 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.51
Marker Score: 232 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.5
Marker Score: 211 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.49
Marker Score: 491 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.49
Marker Score: 242 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.48
Marker Score: 253 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.47
Marker Score: 280 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 0.46
Marker Score: 360 - Cell Name: neural cell (CL0002319)
Fold Change: 0.42
Marker Score: 204 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.42
Marker Score: 135 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.42
Marker Score: 6,545 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.42
Marker Score: 473 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.42
Marker Score: 262 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.41
Marker Score: 394 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.4
Marker Score: 105 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 0.39
Marker Score: 127 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.39
Marker Score: 160 - Cell Name: IgG plasmablast (CL0000982)
Fold Change: 0.37
Marker Score: 103 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.37
Marker Score: 117 - Cell Name: pre-conventional dendritic cell (CL0002010)
Fold Change: 0.37
Marker Score: 109 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 0.37
Marker Score: 265 - Cell Name: promyelocyte (CL0000836)
Fold Change: 0.37
Marker Score: 181 - Cell Name: radial glial cell (CL0000681)
Fold Change: 0.36
Marker Score: 134 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.36
Marker Score: 452 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.35
Marker Score: 592 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.35
Marker Score: 1,439 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.33
Marker Score: 289 - Cell Name: early lymphoid progenitor (CL0000936)
Fold Change: 0.33
Marker Score: 162 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.33
Marker Score: 208 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.33
Marker Score: 221 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.32
Marker Score: 872 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.31
Marker Score: 266 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.3
Marker Score: 321 - Cell Name: malignant cell (CL0001064)
Fold Change: 0.3
Marker Score: 4,072 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 0.3
Marker Score: 303 - Cell Name: erythroblast (CL0000765)
Fold Change: 0.3
Marker Score: 188 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.3
Marker Score: 310 - Cell Name: erythroid lineage cell (CL0000764)
Fold Change: 0.29
Marker Score: 147 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.29
Marker Score: 83 - Cell Name: enteric neuron (CL0007011)
Fold Change: 0.29
Marker Score: 154 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.29
Marker Score: 205 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.28
Marker Score: 182 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.28
Marker Score: 668 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 0.28
Marker Score: 667 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.28
Marker Score: 585 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.27
Marker Score: 86 - Cell Name: stem cell (CL0000034)
Fold Change: 0.27
Marker Score: 631 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.26
Marker Score: 272 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.26
Marker Score: 67 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.26
Marker Score: 8,917 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.26
Marker Score: 118 - Cell Name: oocyte (CL0000023)
Fold Change: 0.25
Marker Score: 63 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.25
Marker Score: 120 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.25
Marker Score: 1,506 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 0.25
Marker Score: 349 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.25
Marker Score: 147 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 0.24
Marker Score: 142 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.24
Marker Score: 229 - Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 0.24
Marker Score: 85 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.24
Marker Score: 927 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.24
Marker Score: 193
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3567494722
Symbol: KIF4A_HUMAN
Name: Chromosome-associated kinesin KIF4A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10978527
Title: Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.
PubMed ID: 10978527
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9168136
Title: Increased chromokinesin immunoreactivity in retinoblastoma cells.
PubMed ID: 9168136
PubMed ID: 11736643
Title: Human kinesin superfamily member 4 is dominantly localized in the nuclear matrix and is associated with chromosomes during mitosis.
PubMed ID: 11736643
PubMed ID: 15297875
Title: Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation.
PubMed ID: 15297875
PubMed ID: 15625105
Title: Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis.
PubMed ID: 15625105
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24812067
Title: Involvement of the kinesin family members KIF4A and KIF5C in intellectual disability and synaptic function.
PubMed ID: 24812067
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 29848660
Title: Fe-S cluster coordination of the chromokinesin KIF4A alters its subcellular localization during mitosis.
PubMed ID: 29848660
DOI: 10.1242/jcs.211433
Sequence Information:
- Length: 1232
- Mass: 139881
- Checksum: AD1B7C2A10AB24DB
- Sequence:
MKEEVKGIPV RVALRCRPLV PKEISEGCQM CLSFVPGEPQ VVVGTDKSFT YDFVFDPSTE QEEVFNTAVA PLIKGVFKGY NATVLAYGQT GSGKTYSMGG AYTAEQENEP TVGVIPRVIQ LLFKEIDKKS DFEFTLKVSY LEIYNEEILD LLCPSREKAQ INIREDPKEG IKIVGLTEKT VLVALDTVSC LEQGNNSRTV ASTAMNSQSS RSHAIFTISL EQRKKSDKNS SFRSKLHLVD LAGSERQKKT KAEGDRLKEG ININRGLLCL GNVISALGDD KKGGFVPYRD SKLTRLLQDS LGGNSHTLMI ACVSPADSNL EETLNTLRYA DRARKIKNKP IVNIDPQTAE LNHLKQQVQQ LQVLLLQAHG GTLPGSITVE PSENLQSLME KNQSLVEENE KLSRGLSEAA GQTAQMLERI ILTEQANEKM NAKLEELRQH AACKLDLQKL VETLEDQELK ENVEIICNLQ QLITQLSDET VACMAAAIDT AVEQEAQVET SPETSRSSDA FTTQHALRQA QMSKELVELN KALALKEALA RKMTQNDSQL QPIQYQYQDN IKELELEVIN LQKEKEELVL ELQTAKKDAN QAKLSERRRK RLQELEGQIA DLKKKLNEQS KLLKLKESTE RTVSKLNQEI RMMKNQRVQL MRQMKEDAEK FRQWKQKKDK EVIQLKERDR KRQYELLKLE RNFQKQSNVL RRKTEEAAAA NKRLKDALQK QREVADKRKE TQSRGMEGTA ARVKNWLGNE IEVMVSTEEA KRHLNDLLED RKILAQDVAQ LKEKKESGEN PPPKLRRRTF SLTEVRGQVS ESEDSITKQI ESLETEMEFR SAQIADLQQK LLDAESEDRP KQRWENIATI LEAKCALKYL IGELVSSKIQ VSKLESSLKQ SKTSCADMQK MLFEERNHFA EIETELQAEL VRMEQQHQEK VLYLLSQLQQ SQMAEKQLEE SVSEKEQQLL STLKCQDEEL EKMREVCEQN QQLLRENEII KQKLTLLQVA SRQKHLPKDT LLSPDSSFEY VPPKPKPSRV KEKFLEQSMD IEDLKYCSEH SVNEHEDGDG DDDEGDDEEW KPTKLVKVSR KNIQGCSCKG WCGNKQCGCR KQKSDCGVDC CCDPTKCRNR QQGKDSLGTV ERTQDSEGSF KLEDPTEVTP GLSFFNPVCA TPNSKILKEM CDVEQVLSKK TPPAPSPFDL PELKHVATEY QENKAPGKKK KRALASNTSF FSGCSPIEEE AH
Genular Protein ID: 2763708203
Symbol: Q59HG1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1235
- Mass: 140339
- Checksum: D9D236876A5C3218
- Sequence:
DRIMKEEVKG IPVRVALRCR PLVPKEISEG CQMCLSFVPG EPQVVVGTDK SFTYDFVFDP STEQEEVFNT AVAPLIKGVF KGYNATVLAY GQTGSGKTYS MGGAYTAEQE NEPTVGVIPR VIQLLFKEID KKSDFEFTLK VSYLEIYNEE ILDLLCPSRE KAQINIREDP KEGIKIVGLT EKTVLVALDT VSCLEQGNNS RTVASTAMNS QSSRSHAIFT ISLEQRKKSD KNSSFRSKLH LVDLAGSERQ KKTKAEGDRL KEGININRGL LCLGNVISAL GDDKKGGFVP YRDSKLTRLL QDSLGGNSHT LMIACVSPAD SNLEETLNTL RYADRARKIK NKPIVNIDPQ TAELNHLKQQ VQQLQVLLLQ AHGGTLPGSI TVEPSENLQS LMEKNQSLVE ENEKLSRGLS EAAGQTAQML ERIIWTEQAN EKMNAKLEEL RQHAACKLDL QKLVETLEDQ ELKENVEIIC NLQQLITQLS DETVACMAAA IDTAVEQEAQ VETSPETSRS SDAFTTQHAL RQAQMSKELV ELNKALALKE ALARKMTQND SQLQPIQYQY QDNIKELELE VINLQKEKEE LVLELQTAKK DANQAKLSER RRKRLQELEG QIADLKKKLN EQSKLLKLKE STERTVSKLN QEIRMMKNQR VQLMRQMKED AEKFRQWKQK KDKEVIQLKE RDRKRQYELL KLERNFQKQS NVLRRKTEEA AAANKRLKDA LQKQREVADK RKETQSRGME GTAARVKNWL GNEIEVMVST EEAKRHLNDL LEDRKILAQD VAQLKEKKES GENPPPKLRR RTFSLTEVRG QVSESEDSIT KQIESLETEM EFRSAQIADL QQKLLDAESE DRPKQRWENI ATILEAKCAL KYLIGELVSS KIQVSKLESS LKQSKTSCAD MQKMLFEERN HFAEIETELQ AELVRMEQQH QEKVLYLLSQ LQQSQMAEKQ LEESVSEKEQ QLLSTLKCQD EELEKMREVC EQNQQLLREN EIIKQKLTLL QVASRQKHLP KDTLLSPDSS FEYVPPKPKP SRVKEKFLEQ SMDIEDLKYC SEHSVNEHED GDGDDDEGDD EEWKPTKLVK VSRKNIQGCS CKGWCGNKQC GCRKQKSDCG VDCCCDPTKC RNRQQGKDSL GTVERTQDSE GSFKLEDPTE VTPGLSFFNP VCATPNSKIL KEMCDVEQVL SKKTPPAPSP FDLPELKHVA TEYQENKAPG KKKKRALASN TSFFSGCSPI EEEAH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.