Details for: IFIT5
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: neural progenitor cell (CL0011020)
Fold Change: 1.7
Marker Score: 6,598 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.65
Marker Score: 1,320 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,754 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,979 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,401 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,403 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 483 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 440 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,715 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,255 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.86
Marker Score: 4,915 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.86
Marker Score: 309 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.81
Marker Score: 796 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,260 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.76
Marker Score: 306 - Cell Name: germ cell (CL0000586)
Fold Change: 0.74
Marker Score: 1,297 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.73
Marker Score: 559 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.73
Marker Score: 378 - Cell Name: brush cell (CL0002204)
Fold Change: 0.7
Marker Score: 642 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.7
Marker Score: 1,427 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.7
Marker Score: 1,713 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.68
Marker Score: 2,867 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 171 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.63
Marker Score: 629 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.63
Marker Score: 9,883 - Cell Name: neural cell (CL0002319)
Fold Change: 0.61
Marker Score: 293 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.6
Marker Score: 668 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.58
Marker Score: 1,032 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.57
Marker Score: 388 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.57
Marker Score: 1,333 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.56
Marker Score: 582 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.55
Marker Score: 289 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 433 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 0.54
Marker Score: 13,858 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.54
Marker Score: 2,329 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.53
Marker Score: 1,088 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.53
Marker Score: 1,002 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.52
Marker Score: 355 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.52
Marker Score: 211 - Cell Name: blood cell (CL0000081)
Fold Change: 0.52
Marker Score: 6,066 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.52
Marker Score: 119 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 0.51
Marker Score: 739 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.51
Marker Score: 208 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.51
Marker Score: 122 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 0.5
Marker Score: 363 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.5
Marker Score: 2,079 - Cell Name: adventitial cell (CL0002503)
Fold Change: 0.5
Marker Score: 123 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.5
Marker Score: 283 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.5
Marker Score: 5,117 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.49
Marker Score: 327 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.49
Marker Score: 383 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.48
Marker Score: 585 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.48
Marker Score: 457 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.48
Marker Score: 3,141 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 0.48
Marker Score: 1,221 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.48
Marker Score: 207 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.48
Marker Score: 160 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.46
Marker Score: 415 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.46
Marker Score: 130 - Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
Fold Change: 0.46
Marker Score: 104 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.46
Marker Score: 463 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.45
Marker Score: 476 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.45
Marker Score: 737 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.45
Marker Score: 15,212 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.44
Marker Score: 186 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.44
Marker Score: 5,006 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.44
Marker Score: 139 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.44
Marker Score: 116 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.43
Marker Score: 668 - Cell Name: neural crest cell (CL0011012)
Fold Change: 0.43
Marker Score: 462 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.43
Marker Score: 135 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 0.43
Marker Score: 370 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.43
Marker Score: 286 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.43
Marker Score: 802 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.42
Marker Score: 267 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.42
Marker Score: 99 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 0.42
Marker Score: 843 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.42
Marker Score: 231 - Cell Name: enteric neuron (CL0007011)
Fold Change: 0.42
Marker Score: 223 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.42
Marker Score: 601 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.41
Marker Score: 180 - Cell Name: leukocyte (CL0000738)
Fold Change: 0.41
Marker Score: 237 - Cell Name: neutrophil (CL0000775)
Fold Change: 0.41
Marker Score: 251 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.41
Marker Score: 857 - Cell Name: pneumocyte (CL0000322)
Fold Change: 0.41
Marker Score: 659 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.41
Marker Score: 21,638 - Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
Fold Change: 0.41
Marker Score: 90 - Cell Name: endothelial cell of artery (CL1000413)
Fold Change: 0.41
Marker Score: 169 - Cell Name: NKp44-positive group 3 innate lymphoid cell, human (CL0001079)
Fold Change: 0.41
Marker Score: 92 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 0.41
Marker Score: 272 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.4
Marker Score: 390 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.4
Marker Score: 81 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 0.4
Marker Score: 184 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.4
Marker Score: 166 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.4
Marker Score: 973 - Cell Name: motor neuron (CL0000100)
Fold Change: 0.4
Marker Score: 236 - Cell Name: pulmonary ionocyte (CL0017000)
Fold Change: 0.4
Marker Score: 243 - Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 0.4
Marker Score: 165 - Cell Name: osteoblast (CL0000062)
Fold Change: 0.39
Marker Score: 211 - Cell Name: type I pneumocyte (CL0002062)
Fold Change: 0.39
Marker Score: 473
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2441577733
Symbol: IFIT5_HUMAN
Name: Interferon-induced protein with tetratricopeptide repeats 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9398535
Title: A novel interferon-inducible gene expressed during myeloid differentiation.
PubMed ID: 9398535
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 20950130
PubMed ID: 21642987
Title: IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA.
PubMed ID: 21642987
DOI: 10.1038/ni.2048
PubMed ID: 25092312
Title: Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5.
PubMed ID: 25092312
PubMed ID: 26334375
Title: IFIT5 positively regulates NF-kappaB signaling through synergizing the recruitment of IkappaB kinase (IKK) to TGF-beta-activated kinase 1 (TAK1).
PubMed ID: 26334375
PubMed ID: 23774268
Title: Crystal structure and nucleotide selectivity of human IFIT5/ISG58.
PubMed ID: 23774268
DOI: 10.1038/cr.2013.80
PubMed ID: 23317505
Title: tRNA binding, structure, and localization of the human interferon-induced protein IFIT5.
PubMed ID: 23317505
PubMed ID: 23334420
Title: Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
PubMed ID: 23334420
DOI: 10.1038/nature11783
Sequence Information:
- Length: 482
- Mass: 55847
- Checksum: 8045BC100384BE05
- Sequence:
MSEIRKDTLK AILLELECHF TWNLLKEDID LFEVEDTIGQ QLEFLTTKSR LALYNLLAYV KHLKGQNKDA LECLEQAEEI IQQEHSDKEE VRSLVTWGNY AWVYYHMDQL EEAQKYTGKI GNVCKKLSSP SNYKLECPET DCEKGWALLK FGGKYYQKAK AAFEKALEVE PDNPEFNIGY AITVYRLDDS DREGSVKSFS LGPLRKAVTL NPDNSYIKVF LALKLQDVHA EAEGEKYIEE ILDQISSQPY VLRYAAKFYR RKNSWNKALE LLKKALEVTP TSSFLHHQMG LCYRAQMIQI KKATHNRPKG KDKLKVDELI SSAIFHFKAA MERDSMFAFA YTDLANMYAE GGQYSNAEDI FRKALRLENI TDDHKHQIHY HYGRFQEFHR KSENTAIHHY LEALKVKDRS PLRTKLTSAL KKLSTKRLCH NALDVQSLSA LGFVYKLEGE KRQAAEYYEK AQKIDPENAE FLTALCELRL SI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.