Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.84
Marker Score: 67,812 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.82
Marker Score: 18,771 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.67
Marker Score: 63,285 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.66
Marker Score: 12,758 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.63
Marker Score: 6,296 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.6
Marker Score: 23,945 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.57
Marker Score: 6,520 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.54
Marker Score: 14,511 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.53
Marker Score: 641 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.5
Marker Score: 92,310 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.49
Marker Score: 1,641 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.46
Marker Score: 29,135 - Cell Name: mural cell (CL0008034)
Fold Change: 1.46
Marker Score: 167,904 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.44
Marker Score: 2,223 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.38
Marker Score: 13,099 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.34
Marker Score: 11,481 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.3
Marker Score: 5,126 - Cell Name: neuron (CL0000540)
Fold Change: 1.28
Marker Score: 5,195 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.25
Marker Score: 341 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.24
Marker Score: 2,962 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.24
Marker Score: 1,822 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 1.23
Marker Score: 2,039 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.23
Marker Score: 366 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.2
Marker Score: 3,437 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.16
Marker Score: 1,217 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 1.14
Marker Score: 9,833 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 1.07
Marker Score: 9,334 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.04
Marker Score: 958 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.01
Marker Score: 319 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,707 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,931 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,394 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.97
Marker Score: 1,724 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.96
Marker Score: 14,974 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.95
Marker Score: 7,088 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,401 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 480 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 434 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.92
Marker Score: 689 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,704 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 0.9
Marker Score: 719 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.87
Marker Score: 1,459 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.87
Marker Score: 1,831 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.86
Marker Score: 5,234 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.85
Marker Score: 4,858 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 306 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.82
Marker Score: 5,269 - Cell Name: keratinocyte (CL0000312)
Fold Change: 0.82
Marker Score: 686 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.82
Marker Score: 1,023 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.81
Marker Score: 920 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.8
Marker Score: 835 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 0.8
Marker Score: 380 - Cell Name: basal cell (CL0000646)
Fold Change: 0.79
Marker Score: 1,020 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.78
Marker Score: 158 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,265 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.76
Marker Score: 582 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.76
Marker Score: 375 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.76
Marker Score: 304 - Cell Name: multi-ciliated epithelial cell (CL0005012)
Fold Change: 0.76
Marker Score: 1,441 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.76
Marker Score: 399 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.75
Marker Score: 235 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.73
Marker Score: 256 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.73
Marker Score: 1,490 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.73
Marker Score: 883 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.73
Marker Score: 3,058 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.73
Marker Score: 2,078 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 372 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 0.71
Marker Score: 493 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 0.7
Marker Score: 5,465 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.7
Marker Score: 2,402 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.7
Marker Score: 572 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.69
Marker Score: 655 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.69
Marker Score: 543 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.68
Marker Score: 787 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.68
Marker Score: 278 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.68
Marker Score: 4,321 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.68
Marker Score: 173 - Cell Name: brush cell (CL0002204)
Fold Change: 0.67
Marker Score: 612 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 0.67
Marker Score: 248 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.66
Marker Score: 674 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.66
Marker Score: 1,619 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.66
Marker Score: 878 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 0.66
Marker Score: 2,071 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.66
Marker Score: 436 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.66
Marker Score: 1,445 - Cell Name: club cell (CL0000158)
Fold Change: 0.64
Marker Score: 749 - Cell Name: epithelial cell (CL0000066)
Fold Change: 0.64
Marker Score: 1,014 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.64
Marker Score: 383 - Cell Name: stem cell (CL0000034)
Fold Change: 0.63
Marker Score: 1,498 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 0.63
Marker Score: 295 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.63
Marker Score: 13,404 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.63
Marker Score: 1,207 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.63
Marker Score: 887 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.62
Marker Score: 620 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.62
Marker Score: 395 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 0.62
Marker Score: 1,398 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.62
Marker Score: 664 - Cell Name: peptic cell (CL0000155)
Fold Change: 0.61
Marker Score: 257 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.61
Marker Score: 867 - Cell Name: blood cell (CL0000081)
Fold Change: 0.61
Marker Score: 7,077
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2577245995
Symbol: EMAL2_HUMAN
Name: Echinoderm microtubule-associated protein-like 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10521658
Title: Sequence and expression patterns of a human EMAP-related protein-2 (HuEMAP-2).
PubMed ID: 10521658
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11694528
Title: The human EMAP-like protein-70 (ELP70) is a microtubule destabilizer that localizes to the mitotic apparatus.
PubMed ID: 11694528
PubMed ID: 24706829
Title: Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical beta-propeller domain.
PubMed ID: 24706829
PubMed ID: 25740311
Title: Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain.
PubMed ID: 25740311
DOI: 10.1042/bj20150039
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 649
- Mass: 70679
- Checksum: F356D3D974D208C9
- Sequence:
MSSFGAGKTK EVIFSVEDGS VKMFLRGRPV PMMIPDELAP TYSLDTRSEL PSCRLKLEWV YGYRGRDCRA NLYLLPTGEI VYFVASVAVL YSVEEQRQRH YLGHNDDIKC LAIHPDMVTI ATGQVAGTTK EGKPLPPHVR IWDSVSLSTL HVLGLGVFDR AVCCVGFSKS NGGNLLCAVD ESNDHMLSVW DWAKETKVVD VKCSNEAVLV ATFHPTDPTV LITCGKSHIY FWTLEGGSLS KRQGLFEKHE KPKYVLCVTF LEGGDVVTGD SGGNLYVWGK GGNRITQAVL GAHDGGVFGL CALRDGTLVS GGGRDRRVVL WGSDYSKLQE VEVPEDFGPV RTVAEGHGDT LYVGTTRNSI LQGSVHTGFS LLVQGHVEEL WGLATHPSRA QFVTCGQDKL VHLWSSDSHQ PLWSRIIEDP ARSAGFHPSG SVLAVGTVTG RWLLLDTETH DLVAIHTDGN EQISVVSFSP DGAYLAVGSH DNLVYVYTVD QGGRKVSRLG KCSGHSSFIT HLDWAQDSSC FVTNSGDYEI LYWDPATCKQ ITSADAVRNM EWATATCVLG FGVFGIWSEG ADGTDINAVA RSHDGKLLAS ADDFGKVHLF SYPCCQPRAL SHKYGGHSSH VTNVAFLWDD SMALTTGGKD TSVLQWRVV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.