Details for: FTSJ1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: germ cell (CL0000586)
Fold Change: 1.82
Marker Score: 3,173 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.69
Marker Score: 1,504 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,738 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,962 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,398 - Cell Name: myeloid dendritic cell (CL0000782)
Fold Change: 0.97
Marker Score: 587 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 0.95
Marker Score: 636 - Cell Name: plasmablast (CL0000980)
Fold Change: 0.95
Marker Score: 1,262 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2,400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.93
Marker Score: 480 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.92
Marker Score: 435 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2,709 - Cell Name: blood cell (CL0000081)
Fold Change: 0.9
Marker Score: 10,510 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,245 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.86
Marker Score: 4,902 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 307 - Cell Name: oogonial cell (CL0000024)
Fold Change: 0.84
Marker Score: 1,211 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: 0.83
Marker Score: 622 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.81
Marker Score: 5,192 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.78
Marker Score: 534 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1,265 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 0.77
Marker Score: 1,513 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.77
Marker Score: 958 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.76
Marker Score: 306 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.76
Marker Score: 951 - Cell Name: oocyte (CL0000023)
Fold Change: 0.76
Marker Score: 187 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.75
Marker Score: 570 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.74
Marker Score: 523 - Cell Name: Unknown (CL0000548)
Fold Change: 0.74
Marker Score: 540 - Cell Name: IgM plasma cell (CL0000986)
Fold Change: 0.73
Marker Score: 255 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.73
Marker Score: 788 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 374 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.72
Marker Score: 380 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 0.71
Marker Score: 744 - Cell Name: brush cell (CL0002204)
Fold Change: 0.7
Marker Score: 640 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.7
Marker Score: 2,933 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.67
Marker Score: 679 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 171 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.66
Marker Score: 1,803 - Cell Name: proerythroblast (CL0000547)
Fold Change: 0.66
Marker Score: 448 - Cell Name: neural cell (CL0002319)
Fold Change: 0.66
Marker Score: 319 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.65
Marker Score: 184 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 0.64
Marker Score: 298 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.63
Marker Score: 663 - Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 0.62
Marker Score: 602 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.62
Marker Score: 390 - Cell Name: Unknown (CL0002371)
Fold Change: 0.62
Marker Score: 654 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.61
Marker Score: 305 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.61
Marker Score: 3,968 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 0.61
Marker Score: 861 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 0.61
Marker Score: 1,917 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 0.61
Marker Score: 406 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.61
Marker Score: 1,279 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: 0.6
Marker Score: 336 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.6
Marker Score: 1,638 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 0.6
Marker Score: 508 - Cell Name: osteoblast (CL0000062)
Fold Change: 0.59
Marker Score: 319 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.59
Marker Score: 4,391 - Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 0.59
Marker Score: 189 - Cell Name: plasma cell (CL0000786)
Fold Change: 0.58
Marker Score: 651 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.57
Marker Score: 383 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 0.56
Marker Score: 984 - Cell Name: enteric neuron (CL0007011)
Fold Change: 0.56
Marker Score: 299 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.56
Marker Score: 308 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.55
Marker Score: 5,578 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 0.55
Marker Score: 2,368 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 0.55
Marker Score: 399 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.55
Marker Score: 364 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.55
Marker Score: 363 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 0.54
Marker Score: 553 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.54
Marker Score: 432 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.54
Marker Score: 309 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 0.54
Marker Score: 28,335 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.54
Marker Score: 142 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 0.53
Marker Score: 470 - Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 0.53
Marker Score: 187 - Cell Name: adventitial cell (CL0002503)
Fold Change: 0.53
Marker Score: 131 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 0.52
Marker Score: 462 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 0.52
Marker Score: 712 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.52
Marker Score: 487 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.52
Marker Score: 537 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 0.52
Marker Score: 378 - Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 0.51
Marker Score: 243 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 0.51
Marker Score: 916 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.51
Marker Score: 171 - Cell Name: pneumocyte (CL0000322)
Fold Change: 0.51
Marker Score: 813 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.5
Marker Score: 4,333 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.5
Marker Score: 736 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.5
Marker Score: 341 - Cell Name: mucus secreting cell (CL0000319)
Fold Change: 0.5
Marker Score: 127 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.5
Marker Score: 2,144 - Cell Name: keratinocyte (CL0000312)
Fold Change: 0.49
Marker Score: 413 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 0.49
Marker Score: 1,199 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.49
Marker Score: 520 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.49
Marker Score: 205 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 0.49
Marker Score: 148 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 0.48
Marker Score: 236 - Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 0.48
Marker Score: 707 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 0.48
Marker Score: 236 - Cell Name: mature B cell (CL0000785)
Fold Change: 0.48
Marker Score: 350
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3156261230
Symbol: TRM7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15162322
Title: Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine-binding protein cause nonsyndromic X-linked mental retardation.
PubMed ID: 15162322
DOI: 10.1086/422507
PubMed ID: 15342698
Title: A splice site mutation in the methyltransferase gene FTSJ1 in Xp11.23 is associated with non-syndromic mental retardation in a large Belgian family (MRX9).
PubMed ID: 15342698
PubMed ID: 18081026
Title: A loss-of-function mutation in the FTSJ1 gene causes nonsyndromic X-linked mental retardation in a Japanese family.
PubMed ID: 18081026
DOI: 10.1002/ajmg.b.30638
PubMed ID: 18401546
Title: Positive association of the FTSJ1 gene polymorphisms with nonsyndromic X-linked mental retardation in young Chinese male subjects.
PubMed ID: 18401546
PubMed ID: 19012053
Title: Genetic variations in FTSJ1 influence cognitive ability in young males in the Chinese Han population.
PubMed ID: 19012053
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25404562
Title: Conservation of an intricate circuit for crucial modifications of the tRNAPhe anticodon loop in eukaryotes.
PubMed ID: 25404562
PubMed ID: 32393790
Title: FTSJ1 regulates tRNA 2'-O-methyladenosine modification and suppresses the malignancy of NSCLC via inhibiting DRAM1 expression.
PubMed ID: 32393790
PubMed ID: 32488007
PubMed ID: 32558197
Title: Intellectual disability-associated gene ftsj1 is responsible for 2'-O-methylation of specific tRNAs.
PubMed ID: 32558197
PubMed ID: 32198346
Title: 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations.
PubMed ID: 32198346
PubMed ID: 33771871
Title: Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability.
PubMed ID: 33771871
PubMed ID: 26310293
Title: Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1.
PubMed ID: 26310293
DOI: 10.1002/humu.22897
PubMed ID: 36720500
Title: The ribose methylation enzyme FTSJ1 has a conserved role in neuron morphology and learning performance.
PubMed ID: 36720500
Sequence Information:
- Length: 329
- Mass: 36079
- Checksum: 9A85D63A4FA80615
- Sequence:
MGRTSKDKRD VYYRLAKENG WRARSAFKLL QLDKEFQLFQ GVTRAVDLCA APGSWSQVLS QKIGGQGSGH VVAVDLQAMA PLPGVVQIQG DITQLSTAKE IIQHFKGCPA DLVVCDGAPD VTGLHDVDEY MQAQLLLAAL NIATHVLKPG GCFVAKIFRG RDVTLLYSQL QVFFSSVLCA KPRSSRNSSI EAFAVCQGYD PPEGFIPDLS KPLLDHSYDP DFNQLDGPTR IIVPFVTCGD LSSYDSDRSY PLDLEGGSEY KYTPPTQPPI SPPYQEACTL KRKGQLAKEI RPQDCPISRV DTFPQPLAAP QCHTLLAPEM EDNEMSCSP
Genular Protein ID: 1313796041
Symbol: B7Z4K4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15772651
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 192
- Mass: 21231
- Checksum: B1691B8E11B3CFD6
- Sequence:
MALNIATHVL KPGGCFVAKI FRGRDVTLLY SQLQVFFSSV LCAKPRSSRN SSIEAFAVCQ GYDPPEGFIP DLSKPLLDHS YDPDFNQLDG PTRIIVPFVT CGDLSSYDSD RSYPLDLEGG SEYKYTPPTQ PPISPPYQEA CTLKRKGQLA KEIRPQDCPI SRVDTFPQPL AAPQCHTLLA PEMEDNEMSC SP
Genular Protein ID: 3619318356
Symbol: B3KN91_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 327
- Mass: 35895
- Checksum: 97417C32D8515DF7
- Sequence:
MGRTSKDKRD VYYRLAKENG WRARSAFKLL QLDKEFQLFQ GVTRAVDLCA APGSWSQVLS RKIGGQGSGH VVAVDLQAMA PLPGVVQIQG DITQLSTAKE IIQHFKGCPA DLVVCDGAPD VTGLHDVDEY MQAQLLLAAL NIATHVLKPG GCFVAKIFRG RDVTLLYSQL QVFFSSVLCA KPRSSRNSSI EAFAVCQGYD PPEGFIPDLS KPLLDHSYDF NQLDGPTRII VPFVTCGDLS SYDSDRSYPL DLEGGSEYKY TPPTQPPISP PYQEACTLKR KGQLAKEIRP QDCPISRVDT FPQPLAAPQC HTLLAPEMED NEMSCSP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.