Details for: FTSJ1

Gene ID: 24140

Symbol: FTSJ1

Ensembl ID: ENSG00000068438

Description: FtsJ RNA 2'-O-methyltransferase 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.82
    Marker Score: 3,173
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.69
    Marker Score: 1,504
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,738
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,962
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,398
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 0.97
    Marker Score: 587
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 0.95
    Marker Score: 636
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.95
    Marker Score: 1,262
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.93
    Marker Score: 480
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 435
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2,709
  • Cell Name: blood cell (CL0000081)
    Fold Change: 0.9
    Marker Score: 10,510
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,245
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.86
    Marker Score: 4,902
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.85
    Marker Score: 307
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.84
    Marker Score: 1,211
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.83
    Marker Score: 622
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.81
    Marker Score: 5,192
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.78
    Marker Score: 534
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,265
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 0.77
    Marker Score: 1,513
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.77
    Marker Score: 958
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.76
    Marker Score: 306
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.76
    Marker Score: 951
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.76
    Marker Score: 187
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.75
    Marker Score: 570
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.74
    Marker Score: 523
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.74
    Marker Score: 540
  • Cell Name: IgM plasma cell (CL0000986)
    Fold Change: 0.73
    Marker Score: 255
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.73
    Marker Score: 788
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.72
    Marker Score: 374
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.72
    Marker Score: 380
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.71
    Marker Score: 744
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.7
    Marker Score: 640
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7
    Marker Score: 2,933
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.67
    Marker Score: 679
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 171
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.66
    Marker Score: 1,803
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.66
    Marker Score: 448
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.66
    Marker Score: 319
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.65
    Marker Score: 184
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.64
    Marker Score: 298
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.63
    Marker Score: 663
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 0.62
    Marker Score: 602
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 0.62
    Marker Score: 390
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.62
    Marker Score: 654
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.61
    Marker Score: 305
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.61
    Marker Score: 3,968
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 0.61
    Marker Score: 861
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 0.61
    Marker Score: 1,917
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.61
    Marker Score: 406
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.61
    Marker Score: 1,279
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 0.6
    Marker Score: 336
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.6
    Marker Score: 1,638
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.6
    Marker Score: 508
  • Cell Name: osteoblast (CL0000062)
    Fold Change: 0.59
    Marker Score: 319
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.59
    Marker Score: 4,391
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 0.59
    Marker Score: 189
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.58
    Marker Score: 651
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.57
    Marker Score: 383
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 0.56
    Marker Score: 984
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 0.56
    Marker Score: 299
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.56
    Marker Score: 308
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.55
    Marker Score: 5,578
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 0.55
    Marker Score: 2,368
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 0.55
    Marker Score: 399
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.55
    Marker Score: 364
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.55
    Marker Score: 363
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 0.54
    Marker Score: 553
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.54
    Marker Score: 432
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 0.54
    Marker Score: 309
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.54
    Marker Score: 28,335
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.54
    Marker Score: 142
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 0.53
    Marker Score: 470
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 0.53
    Marker Score: 187
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.53
    Marker Score: 131
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 0.52
    Marker Score: 462
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 0.52
    Marker Score: 712
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 0.52
    Marker Score: 487
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.52
    Marker Score: 537
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 0.52
    Marker Score: 378
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 0.51
    Marker Score: 243
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 0.51
    Marker Score: 916
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 0.51
    Marker Score: 171
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 0.51
    Marker Score: 813
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.5
    Marker Score: 4,333
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5
    Marker Score: 736
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.5
    Marker Score: 341
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.5
    Marker Score: 127
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.5
    Marker Score: 2,144
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.49
    Marker Score: 413
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 0.49
    Marker Score: 1,199
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.49
    Marker Score: 520
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.49
    Marker Score: 205
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 0.49
    Marker Score: 148
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.48
    Marker Score: 236
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 0.48
    Marker Score: 707
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 0.48
    Marker Score: 236
  • Cell Name: mature B cell (CL0000785)
    Fold Change: 0.48
    Marker Score: 350

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** FTSJ1 is a member of the TRM7 family of RNA methyltransferases, which are responsible for the 2'-O-methylation of tRNA molecules. This post-transcriptional modification is essential for the proper functioning of tRNA, as it enables the recognition of codons during translation. FTSJ1 exhibits high sequence homology with other TRM7 family members, suggesting a conserved mechanism of action. Notably, FTSJ1 is specifically expressed in germ cells, extravillous trophoblasts, and neural tissues, highlighting its unique role in these cell types. **Pathways and Functions:** FTSJ1 is involved in several critical pathways, including: 1. **tRNA modification**: FTSJ1 is responsible for the 2'-O-methylation of tRNA molecules, which is essential for the recognition of codons during translation. 2. **Cytoplasmic translation**: FTSJ1 plays a crucial role in the regulation of cytoplasmic translation, ensuring the proper translation of mRNAs. 3. **Neurogenesis**: FTSJ1 has been implicated in the regulation of neurogenesis, particularly in the context of GABAergic interneurons and radial glial cells. 4. **Metabolism of RNA**: FTSJ1 is involved in the regulation of RNA metabolism, including the processing of tRNA and other small RNAs. **Proteins:** FTSJ1 has been associated with several proteins, including TRM7_HUMAN, B7Z4K4_HUMAN, and B3KN91_HUMAN, which are involved in RNA methyltransferase activity. **Clinical Significance:** The dysregulation of FTSJ1 has been implicated in various diseases, including: 1. **Neurodevelopmental disorders**: Abnormalities in FTSJ1 expression have been linked to neurodevelopmental disorders, such as autism spectrum disorder and schizophrenia. 2. **Cancer**: FTSJ1 has been shown to play a role in the regulation of tRNA expression in cancer cells, which may contribute to tumorigenesis. 3. **Neurodegenerative diseases**: FTSJ1 has been implicated in the regulation of tRNA expression in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. In conclusion, FTSJ1 is a multifaceted gene that plays a critical role in RNA methyltransferase activity, particularly in the context of tRNA modification. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the mechanisms of FTSJ1 and its clinical significance.

Genular Protein ID: 3156261230

Symbol: TRM7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9UET6 B2RCJ0 O75670

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 12 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 6 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HAMAP 2 HAMAP-Rule 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 Rhea 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15162322

Title: Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine-binding protein cause nonsyndromic X-linked mental retardation.

PubMed ID: 15162322

DOI: 10.1086/422507

PubMed ID: 15342698

Title: A splice site mutation in the methyltransferase gene FTSJ1 in Xp11.23 is associated with non-syndromic mental retardation in a large Belgian family (MRX9).

PubMed ID: 15342698

DOI: 10.1136/jmg.2004.019000

PubMed ID: 18081026

Title: A loss-of-function mutation in the FTSJ1 gene causes nonsyndromic X-linked mental retardation in a Japanese family.

PubMed ID: 18081026

DOI: 10.1002/ajmg.b.30638

PubMed ID: 18401546

Title: Positive association of the FTSJ1 gene polymorphisms with nonsyndromic X-linked mental retardation in young Chinese male subjects.

PubMed ID: 18401546

DOI: 10.1007/s10038-008-0287-x

PubMed ID: 19012053

Title: Genetic variations in FTSJ1 influence cognitive ability in young males in the Chinese Han population.

PubMed ID: 19012053

DOI: 10.1080/01677060802337299

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25404562

Title: Conservation of an intricate circuit for crucial modifications of the tRNAPhe anticodon loop in eukaryotes.

PubMed ID: 25404562

DOI: 10.1261/rna.047639.114

PubMed ID: 32393790

Title: FTSJ1 regulates tRNA 2'-O-methyladenosine modification and suppresses the malignancy of NSCLC via inhibiting DRAM1 expression.

PubMed ID: 32393790

DOI: 10.1038/s41419-020-2525-x

PubMed ID: 32488007

Title:

PubMed ID: 32488007

DOI: 10.1038/s41419-020-2623-9

PubMed ID: 32558197

Title: Intellectual disability-associated gene ftsj1 is responsible for 2'-O-methylation of specific tRNAs.

PubMed ID: 32558197

DOI: 10.15252/embr.202050095

PubMed ID: 32198346

Title: 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations.

PubMed ID: 32198346

DOI: 10.1038/s41467-020-15140-z

PubMed ID: 33771871

Title: Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability.

PubMed ID: 33771871

DOI: 10.1126/sciadv.abf3072

PubMed ID: 26310293

Title: Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1.

PubMed ID: 26310293

DOI: 10.1002/humu.22897

PubMed ID: 36720500

Title: The ribose methylation enzyme FTSJ1 has a conserved role in neuron morphology and learning performance.

PubMed ID: 36720500

DOI: 10.26508/lsa.202201877

Sequence Information:

  • Length: 329
  • Mass: 36079
  • Checksum: 9A85D63A4FA80615
  • Sequence:
    • MGRTSKDKRD VYYRLAKENG WRARSAFKLL QLDKEFQLFQ GVTRAVDLCA APGSWSQVLS 
QKIGGQGSGH VVAVDLQAMA PLPGVVQIQG DITQLSTAKE IIQHFKGCPA DLVVCDGAPD 
VTGLHDVDEY MQAQLLLAAL NIATHVLKPG GCFVAKIFRG RDVTLLYSQL QVFFSSVLCA 
KPRSSRNSSI EAFAVCQGYD PPEGFIPDLS KPLLDHSYDP DFNQLDGPTR IIVPFVTCGD 
LSSYDSDRSY PLDLEGGSEY KYTPPTQPPI SPPYQEACTL KRKGQLAKEI RPQDCPISRV 
DTFPQPLAAP QCHTLLAPEM EDNEMSCSP

Genular Protein ID: 1313796041

Symbol: B7Z4K4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z4K4

Database IDs:

ARBA 3 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 2 GO 3 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 192
  • Mass: 21231
  • Checksum: B1691B8E11B3CFD6
  • Sequence:
    • MALNIATHVL KPGGCFVAKI FRGRDVTLLY SQLQVFFSSV LCAKPRSSRN SSIEAFAVCQ 
GYDPPEGFIP DLSKPLLDHS YDPDFNQLDG PTRIIVPFVT CGDLSSYDSD RSYPLDLEGG 
SEYKYTPPTQ PPISPPYQEA CTLKRKGQLA KEIRPQDCPI SRVDTFPQPL AAPQCHTLLA 
PEMEDNEMSC SP

Genular Protein ID: 3619318356

Symbol: B3KN91_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KN91

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 12 ChiTaRS 1 DNASU 1 EC 1 EMBL 2 GO 5 Gene3D 1 Genevisible 1 GenomeRNAi 1 HAMAP 2 HAMAP-Rule 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 Rhea 3 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 327
  • Mass: 35895
  • Checksum: 97417C32D8515DF7
  • Sequence:
    • MGRTSKDKRD VYYRLAKENG WRARSAFKLL QLDKEFQLFQ GVTRAVDLCA APGSWSQVLS 
RKIGGQGSGH VVAVDLQAMA PLPGVVQIQG DITQLSTAKE IIQHFKGCPA DLVVCDGAPD 
VTGLHDVDEY MQAQLLLAAL NIATHVLKPG GCFVAKIFRG RDVTLLYSQL QVFFSSVLCA 
KPRSSRNSSI EAFAVCQGYD PPEGFIPDLS KPLLDHSYDF NQLDGPTRII VPFVTCGDLS 
SYDSDRSYPL DLEGGSEYKY TPPTQPPISP PYQEACTLKR KGQLAKEIRP QDCPISRVDT 
FPQPLAAPQC HTLLAPEMED NEMSCSP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.