Genular: Defining Cellular Identity and Function

Details for: Ada

Gene ID: 24165

Symbol: Ada

Ensembl ID: ENSRNOG00000010265

Description: adenosine deaminase

Associated with

Drug adme
(R-RNO-9748784)
Metabolism
(R-RNO-1430728)
Metabolism of nucleotides
(R-RNO-15869)
Nucleotide salvage
(R-RNO-8956321)
Purine salvage
(R-RNO-74217)
Ribavirin adme
(R-RNO-9755088)
2'-deoxyadenosine deaminase activity
(GO:0046936)
Adenosine catabolic process
(GO:0006154)
Adenosine deaminase activity
(GO:0004000)
Adenosine metabolic process
(GO:0046085)
Allantoin metabolic process
(GO:0000255)
Alpha-beta t cell differentiation
(GO:0046632)
Amide catabolic process
(GO:0043605)
Amp catabolic process
(GO:0006196)
Amp salvage
(GO:0044209)
Apoptotic process
(GO:0006915)
B cell proliferation
(GO:0042100)
Calcium-mediated signaling
(GO:0019722)
Cell adhesion
(GO:0007155)
Cell surface
(GO:0009986)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle lumen
(GO:0060205)
Cytosol
(GO:0005829)
Damp catabolic process
(GO:0046059)
Datp catabolic process
(GO:0046061)
Deaminase activity
(GO:0019239)
Dendrite cytoplasm
(GO:0032839)
Deoxyadenosine catabolic process
(GO:0006157)
Embryonic digestive tract development
(GO:0048566)
External side of plasma membrane
(GO:0009897)
Extracellular space
(GO:0005615)
Germinal center b cell differentiation
(GO:0002314)
Germinal center formation
(GO:0002467)
Gmp salvage
(GO:0032263)
Histamine secretion
(GO:0001821)
Hypoxanthine biosynthetic process
(GO:0046101)
Hypoxanthine salvage
(GO:0043103)
Inosine biosynthetic process
(GO:0046103)
In utero embryonic development
(GO:0001701)
Leukocyte migration
(GO:0050900)
Liver development
(GO:0001889)
Lung alveolus development
(GO:0048286)
Lung development
(GO:0030324)
Lysosome
(GO:0005764)
Mature b cell apoptotic process
(GO:0002901)
Membrane
(GO:0016020)
Mucus secretion
(GO:0070254)
Negative regulation of adenosine receptor signaling pathway
(GO:0060169)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of circadian sleep/wake cycle, non-rem sleep
(GO:0042323)
Negative regulation of inflammatory response
(GO:0050728)
Negative regulation of leukocyte migration
(GO:0002686)
Negative regulation of mature b cell apoptotic process
(GO:0002906)
Negative regulation of mucus secretion
(GO:0070256)
Negative regulation of penile erection
(GO:0060407)
Negative regulation of thymocyte apoptotic process
(GO:0070244)
Neuronal cell body
(GO:0043025)
Penile erection
(GO:0043084)
Peyer's patch development
(GO:0048541)
Placenta development
(GO:0001890)
Plasma membrane
(GO:0005886)
Positive regulation of alpha-beta t cell differentiation
(GO:0046638)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of calcium-mediated signaling
(GO:0050850)
Positive regulation of germinal center formation
(GO:0002636)
Positive regulation of heart rate
(GO:0010460)
Positive regulation of smooth muscle contraction
(GO:0045987)
Positive regulation of t cell activation
(GO:0050870)
Positive regulation of t cell differentiation
(GO:0045582)
Positive regulation of t cell differentiation in thymus
(GO:0033089)
Positive regulation of t cell receptor signaling pathway
(GO:0050862)
Purine nucleoside binding
(GO:0001883)
Purine nucleotide salvage
(GO:0032261)
Purine ribonucleoside monophosphate biosynthetic process
(GO:0009168)
Regulation of cell-cell adhesion mediated by integrin
(GO:0033632)
Regulation of circadian sleep/wake cycle, sleep
(GO:0045187)
Regulation of t cell differentiation
(GO:0045580)
Regulation of t cell differentiation in thymus
(GO:0033081)
Response to cadmium ion
(GO:0046686)
Response to hydrogen peroxide
(GO:0042542)
Response to hypoxia
(GO:0001666)
Response to inorganic substance
(GO:0010035)
Response to l-arginine
(GO:1903576)
Response to purine-containing compound
(GO:0014074)
Response to vitamin e
(GO:0033197)
Response to xenobiotic stimulus
(GO:0009410)
Smooth muscle contraction
(GO:0006939)
T cell activation
(GO:0042110)
T cell differentiation
(GO:0030217)
T cell differentiation in thymus
(GO:0033077)
T cell receptor signaling pathway
(GO:0050852)
Thymocyte apoptotic process
(GO:0070242)
Trophectodermal cell differentiation
(GO:0001829)
Xanthine biosynthetic process
(GO:0046111)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Adenosine deaminase

Genular Protein ID: 3117586343

Symbol: ADA_RAT

Name: Adenosine deaminase

UniProtKB Accession Codes:

Q920P6

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8783262

Title: Adenosine deaminase in rodent median eminence: detection by antibody to the mouse enzyme and co-localization with adenosine deaminase-complexing protein (CD26).

PubMed ID: 8783262

DOI: 10.1016/0306-4522(96)00049-8

PubMed ID: 19900420

Title: AMP deaminase and adenosine deaminase activities in liver and brain regions in acute ammonia intoxication and subacute toxic hepatitis.

PubMed ID: 19900420

DOI: 10.1016/j.brainres.2009.10.073

Sequence Information:

Length: 352
Mass: 39899
Checksum: F689ADFD39682FC6
Sequence:

MAQTPAFNKP KVELHVHLDG AIKPETILYY GKKRGIDLPA DTVEGLRNII GMDKPLSLPD 
FLAKFDYYMP AIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVDPIPWNQA 
EGDLTPDEVV DLVNQGLQEG EQAFGIKVRS ILCCMRHQPS WSPEVLELCK KYHQKTVVAM 
DLAGDETIEG SSLFPGHVEA YEGAVKDGIH RTVHAGEVGS AEVVREAVDI LKTERVGHGY 
HTIEDEALYN RLLKENMHFE VCPWSSYLTG AWNPKTTHAV VRFKDDQANY SLNSDDPLIF 
KSTVDTDYQM VKKDMGFTEE EFKRLNINAA KSSFLPEDEK KELLERLYKE YQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.