Genular: Defining Cellular Identity and Function

Details for: Adra2b

Gene ID: 24174

Symbol: Adra2b

Ensembl ID: ENSRNOG00000013887

Description: adrenoceptor alpha 2B

Associated with

Adrenaline signalling through alpha-2 adrenergic receptor
(R-RNO-392023)
Adrenoceptors
(R-RNO-390696)
Amine ligand-binding receptors
(R-RNO-375280)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (i) signalling events
(R-RNO-418594)
G alpha (z) signalling events
(R-RNO-418597)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Hemostasis
(R-RNO-109582)
Platelet activation, signaling and aggregation
(R-RNO-76002)
Platelet aggregation (plug formation)
(R-RNO-76009)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adenylate cyclase-activating adrenergic receptor signaling pathway
(GO:0071880)
Adrenergic receptor activity
(GO:0004935)
Adrenergic receptor signaling pathway
(GO:0071875)
Alpha2-adrenergic receptor activity
(GO:0004938)
Angiogenesis
(GO:0001525)
Cell surface
(GO:0009986)
Cytosol
(GO:0005829)
Epinephrine binding
(GO:0051379)
Female pregnancy
(GO:0007565)
G protein-coupled receptor signaling pathway
(GO:0007186)
Intracellular membrane-bounded organelle
(GO:0043231)
Mapk cascade
(GO:0000165)
Plasma membrane
(GO:0005886)
Platelet activation
(GO:0030168)
Positive regulation of blood pressure
(GO:0045777)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of uterine smooth muscle contraction
(GO:0070474)
Protein binding
(GO:0005515)
Regulation of vascular associated smooth muscle contraction
(GO:0003056)

Other Information

Proteins

Alpha-2B adrenergic receptor

Genular Protein ID: 2127363290

Symbol: ADA2B_RAT

Name: Alpha-2B adrenergic receptor

UniProtKB Accession Codes:

P19328 Q63021 Q925E4

Database IDs:

Citations:

PubMed ID: 2158103

Title: Molecular characterization of a rat alpha 2B-adrenergic receptor.

PubMed ID: 2158103

DOI: 10.1073/pnas.87.8.3102

PubMed ID: 15993847

Title: Cloning and functional characterization of the rat alpha2B-adrenergic receptor gene promoter region: evidence for binding sites for erythropoiesis-related transcription factors GATA1 and NF-E2.

PubMed ID: 15993847

DOI: 10.1016/j.bcp.2005.05.024

PubMed ID: 7755946

Title: Differential sodium regulation between salt-sensitive and salt-resistant Sabra rats is not due to any mutation in the renal alpha 2B-adrenoceptor gene.

PubMed ID: 7755946

DOI: 10.1016/0895-7061(94)00177-d

Sequence Information:

Length: 453
Mass: 50369
Checksum: CBA69CE23EACB511
Sequence:

MSGPTMDHQE PYSVQATAAI ASAITFLILF TIFGNALVIL AVLTSRSLRA PQNLFLVSLA 
AADILVATLI IPFSLANELL GYWYFWRAWC EVYLALDVLF CTSSIVHLCA ISLDRYWAVS 
RALEYNSKRT PRRIKCIILT VWLIAAVISL PPLIYKGDQR PEPRGLPQCE LNQEAWYILA 
SSIGSFFAPC LIMILVYLRI YVIAKRSHCR GLGAKRGSGE GESKKPQPVA GGVPTSAKVP 
TLVSPLSSVG EANGHPKPPR EKEEGETPED PEARALPPTW SALPRSGQGQ KKGTSGATAE 
EGDEEDEEEV EECEPQTLPA SPASVCNPPL QQPQTSRVLA TLRGQVLLGK NVGVASGQWW 
RRRTQLSREK RFTFVLAVVI GVFVVCWFPF FFSYSLGAIC PQHCKVPHGL FQFFFWIGYC 
NSSLNPVIYT VFNQDFRRAF RRILCRPWTQ TGW

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.