Genular: Defining Cellular Identity and Function

Details for: Adra2c

Gene ID: 24175

Symbol: Adra2c

Ensembl ID: ENSRNOG00000009299

Description: adrenoceptor alpha 2C

Associated with

Adrenaline,noradrenaline inhibits insulin secretion
(R-RNO-400042)
Adrenaline signalling through alpha-2 adrenergic receptor
(R-RNO-392023)
Adrenoceptors
(R-RNO-390696)
Amine ligand-binding receptors
(R-RNO-375280)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (i) signalling events
(R-RNO-418594)
G alpha (z) signalling events
(R-RNO-418597)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Hemostasis
(R-RNO-109582)
Integration of energy metabolism
(R-RNO-163685)
Metabolism
(R-RNO-1430728)
Metabolism of proteins
(R-RNO-392499)
Platelet activation, signaling and aggregation
(R-RNO-76002)
Platelet aggregation (plug formation)
(R-RNO-76009)
Regulation of insulin secretion
(R-RNO-422356)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Surfactant metabolism
(R-RNO-5683826)
Adenylate cyclase-activating adrenergic receptor signaling pathway
(GO:0071880)
Adrenergic receptor signaling pathway
(GO:0071875)
Alpha-2a adrenergic receptor binding
(GO:0031694)
Alpha2-adrenergic receptor activity
(GO:0004938)
Axon
(GO:0030424)
Axon terminus
(GO:0043679)
Cytoplasm
(GO:0005737)
Epinephrine binding
(GO:0051379)
Female pregnancy
(GO:0007565)
Glutamatergic synapse
(GO:0098978)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Negative regulation of uterine smooth muscle contraction
(GO:0070473)
Neuronal cell body
(GO:0043025)
Plasma membrane
(GO:0005886)
Platelet activation
(GO:0030168)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of vasoconstriction
(GO:0045907)
Postsynaptic density membrane
(GO:0098839)
Postsynaptic membrane
(GO:0045211)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)

Other Information

Proteins

Alpha-2C adrenergic receptor

Genular Protein ID: 1178618627

Symbol: ADA2C_RAT

Name: Alpha-2C adrenergic receptor

UniProtKB Accession Codes:

P22086

Database IDs:

Citations:

PubMed ID: 1704126

Title: Cloning and expression of a rat brain alpha 2B-adrenergic receptor.

PubMed ID: 1704126

DOI: 10.1073/pnas.88.3.1019

PubMed ID: 1704314

Title: The rat alpha 2-C4 adrenergic receptor gene encodes a novel pharmacological subtype.

PubMed ID: 1704314

DOI: 10.1016/0014-5793(91)80080-m

PubMed ID: 1645350

Title: Isolation of rat genomic clones encoding subtypes of the alpha 2-adrenergic receptor. Identification of a unique receptor subtype.

PubMed ID: 1645350

DOI: 10.1016/s0021-9258(18)99248-3

Sequence Information:

Length: 458
Mass: 49864
Checksum: 6846C2AF963B33BF
Sequence:

MASPALAAAL AAAAAEGPNG SDAGEWGSGG GANASGTDWG PPPGQYSAGA VAGLAAVVGF 
LIVFTVVGNV LVVIAVLTSR ALRAPQNLFL VSLASADILV ATLVMPFSLA NELMAYWYFG 
QVWCGVYLAL DVLFCTSSIV HLCAISLDRY WSVTQAVEYN LKRTPRRVKA TIVAVWLISA 
VISFPPLVSF YRRPDGAAYP QCGLNDETWY ILSSCIGSFF APCLIMGLVY ARIYRVAKLR 
TRTLSEKRGP AGPDGASPTT ENGLGKAAGE NGHCAPPRTE VEPDESSAAE RRRRRGALRR 
GGRRREGAEG DTGSADGPGP GLAAEQGART ASRSPGPGGR LSRASSRSVE FFLSRRRRAR 
SSVCRRKVAQ AREKRFTFVL AVVMGVFVLC WFPFFFSYSL YGICREACQL PEPLFKFFFW 
IGYCNSSLNP VIYTVFNQDF RRSFKHILFR RRRRGFRQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.