Genular: Defining Cellular Identity and Function

Details for: Akr1b1

Gene ID: 24192

Symbol: Akr1b1

Ensembl ID: ENSRNOG00000009513

Description: aldo-keto reductase family 1 member B1

Associated with

Fructose biosynthesis
(R-RNO-5652227)
Fructose metabolism
(R-RNO-5652084)
Metabolism
(R-RNO-1430728)
Metabolism of carbohydrates
(R-RNO-71387)
Metabolism of lipids
(R-RNO-556833)
Metabolism of steroid hormones
(R-RNO-196071)
Metabolism of steroids
(R-RNO-8957322)
Pregnenolone biosynthesis
(R-RNO-196108)
Alditol:nadp+ 1-oxidoreductase activity
(GO:0004032)
Allyl-alcohol dehydrogenase activity
(GO:0047655)
Cellular hyperosmotic salinity response
(GO:0071475)
Cellular response to hydrogen peroxide
(GO:0070301)
Cellular response to methylglyoxal
(GO:0097238)
Cellular response to peptide
(GO:1901653)
Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity
(GO:0018505)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Daunorubicin metabolic process
(GO:0044597)
Doxorubicin metabolic process
(GO:0044598)
Epithelial cell maturation
(GO:0002070)
Extracellular space
(GO:0005615)
Fructose biosynthetic process
(GO:0046370)
Glyceraldehyde oxidoreductase activity
(GO:0043795)
Glycerol dehydrogenase [nadp+] activity
(GO:0047956)
Inner medullary collecting duct development
(GO:0072061)
L-ascorbic acid biosynthetic process
(GO:0019853)
L-glucuronate reductase activity
(GO:0047939)
Mast cell granule
(GO:0042629)
Maternal process involved in female pregnancy
(GO:0060135)
Metanephric collecting duct development
(GO:0072205)
Monosaccharide metabolic process
(GO:0005996)
Nadp-retinol dehydrogenase activity
(GO:0052650)
Negative regulation of apoptotic process
(GO:0043066)
Norepinephrine metabolic process
(GO:0042415)
Nucleoplasm
(GO:0005654)
Oxidoreductase activity
(GO:0016491)
Paranodal junction
(GO:0033010)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane bounded cell projection cytoplasm
(GO:0032838)
Positive regulation of receptor signaling pathway via jak-stat
(GO:0046427)
Positive regulation of smooth muscle cell proliferation
(GO:0048661)
Prostaglandin h2 endoperoxidase reductase activity
(GO:0036130)
Prostaglandin metabolic process
(GO:0006693)
Regulation of urine volume
(GO:0035809)
Renal water homeostasis
(GO:0003091)
Response to organic substance
(GO:0010033)
Response to thyroid hormone
(GO:0097066)
Retinal dehydrogenase activity
(GO:0001758)
Retinoid metabolic process
(GO:0001523)
Retinol metabolic process
(GO:0042572)
Schmidt-lanterman incisure
(GO:0043220)
Schwann cell microvillus
(GO:0097454)
Sorbitol biosynthetic process
(GO:0006061)
Stress-activated protein kinase signaling cascade
(GO:0031098)
Tissue homeostasis
(GO:0001894)

Other Information

Proteins

Aldo-keto reductase family 1 member B1

Genular Protein ID: 2197817784

Symbol: ALDR_RAT

Name: Aldo-keto reductase family 1 member B1

UniProtKB Accession Codes:

P07943

Database IDs:

Citations:

PubMed ID: 3111886

Title: Aldose reductase and p-crystallin belong to the same protein superfamily as aldehyde reductase.

PubMed ID: 3111886

DOI: 10.1016/0014-5793(87)80905-5

PubMed ID: 1748296

Title: Characterization of the aldose reductase-encoding gene family in rat.

PubMed ID: 1748296

DOI: 10.1016/0378-1119(91)90326-7

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7498172

Title: Long-term induction of an aldose reductase protein by basic fibroblast growth factor in rat astrocytes in vitro.

PubMed ID: 7498172

DOI: 10.1002/elps.11501601205

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 316
Mass: 35797
Checksum: D6D07843B6850002
Sequence:

MASHLELNNG TKMPTLGLGT WKSPPGQVTE AVKVAIDMGY RHIDCAQVYQ NEKEVGVALQ 
EKLKEQVVKR QDLFIVSKLW CTFHDQSMVK GACQKTLSDL QLDYLDLYLI HWPTGFKPGP 
DYFPLDASGN VIPSDTDFVD TWTAMEQLVD EGLVKAIGVS NFNPLQIERI LNKPGLKYKP 
AVNQIECHPY LTQEKLIEYC HCKGIVVTAY SPLGSPDRPW AKPEDPSLLE DPRIKEIAAK 
YNKTTAQVLI RFPIQRNLVV IPKSVTPARI AENFKVFDFE LSNEDMATLL SYNRNWRVCA 
LMSCAKHKDY PFHAEV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Akr1b1

Associated with

Other Information

Aldose reductase and p-crystallin belong to the same protein superfamily as aldehyde reductase. PubMed ID: 3111886

Characterization of the aldose reductase-encoding gene family in rat. PubMed ID: 1748296

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334